Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mariana N. Nikolova"'
Autor:
Gergana Deevska, Manjula Sunkara, Claudia Karakashian, Benjamin Peppers, Andrew J. Morris, Mariana N. Nikolova-Karakashian
Publikováno v:
Journal of Lipid Research, Vol 55, Iss 10, Pp 2041-2052 (2014)
In hepatocytes, aging-associated decline in GSH has been linked to activation of neutral SMase (nSMase), accumulation of bioactive ceramide, and inflammation. In this study, we seek to test whether dietary supplementation with the cysteine precursor,
Externí odkaz:
https://doaj.org/article/01cc54f6c1f044eda2c43433ea7df32d
Autor:
Jennifer S. Moylan, Jeffrey D. Smith, Erin M. Wolf Horrell, Julie B. McLean, Gergana M. Deevska, Mark R. Bonnell, Mariana N. Nikolova-Karakashian, Michael B. Reid
Publikováno v:
Redox Biology, Vol 2, Iss C, Pp 910-920 (2014)
Aims: Sphingolipid and oxidant signaling affect glucose uptake, atrophy, and force production of skeletal muscle similarly and both are stimulated by tumor necrosis factor (TNF), suggesting a connection between systems. Sphingolipid signaling is init
Externí odkaz:
https://doaj.org/article/0fe729e47d2547bda79a6dd352d6f028
Publikováno v:
Journal of Lipid Research, Vol 48, Iss 11, Pp 2443-2452 (2007)
Oxidative stress and inflammation are fundamental for the onset of aging and appear to be causatively linked. Previously, we reported that hepatocytes from aged rats, compared with young rats, are hyperresponsive to interleukin-1β (IL-1β) stimulati
Externí odkaz:
https://doaj.org/article/6f35b2c24e33429cbd390460962015bb
Autor:
Natalia V. Giltiay, Alexander A. Karakashian, Alexander P. Alimov, Sandy Ligthle, Mariana N. Nikolova-Karakashian
Publikováno v:
Journal of Lipid Research, Vol 46, Iss 11, Pp 2497-2505 (2005)
Interleukin-1β (IL-1β) is a major inducer of liver acute-phase protein expression in response to infection. Several transcription factors, including CCAAT/enhancer binding protein (C/EBP), are known mediators in this process, although the mechanism
Externí odkaz:
https://doaj.org/article/a742162ce9d84a8fa7604f4f592d24e5
Autor:
Gabriela Ambrozova, Milan Ciz, Mariana N. Nikolova, Veselin Kussovski, Antonín Lojek, Petko Denev, Maria Kratchanova
The current survey investigates the effect of four polysaccharides isolated from fresh leek or alcohol insoluble substances (AIS) of leek on the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) from phagocytes. The abil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4d0a85e12ff0f415e57cb7d00357012
https://europepmc.org/articles/PMC3751262/
https://europepmc.org/articles/PMC3751262/
Publikováno v:
The Journal of biological chemistry. 287(53)
FoxO1 transcription factor controls the glucose and lipid metabolism, as well as cell proliferation and stress response. Akt, activated by insulin and other growth factors, phosphorylates FoxO1 causing its nuclear export and activity suppression. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2d77e9a4fa91cbba8f69d6ab3e21d87f
https://pubmed.ncbi.nlm.nih.gov/23105097
https://pubmed.ncbi.nlm.nih.gov/23105097
Publikováno v:
Sphingolipids as Signaling and Regulatory Molecules
Evidence has consistently indicated that activation of sphingomyelinases and/or ceramide synthases and the resulting accumulation of ceramide mediate cellular responses to stressors such as lipopolysaccharide, interleukin 1beta, tumor necrosis factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ce0ea1fc722823ce9fcbba0f9c5bd49
https://pubmed.ncbi.nlm.nih.gov/20919648
https://pubmed.ncbi.nlm.nih.gov/20919648
Publikováno v:
Journal of the Science of Food and Agriculture.
BACKGROUND: Leek (Allium porrum) is very commonly used vegetable in Bulgaria and is distinctive with high content of bioactive components. Previously we obtained five crude pectic polysaccharides from leek through consecutive extraction. Some of them
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5937dabf88faa376d21acd9f4c43ea9e
https://doi.org/10.1002/jsfa.4050
https://doi.org/10.1002/jsfa.4050
Publikováno v:
International Journal of Biochemistry. 24:447-453
1. 1. Plasma membranes were treated with phospholipase A2, phospholipase C or phospholipase D. The phosphatidylethanolamine: ceramide-phosphorylethanolamine transferase was deactivated by phospholipase C treatment, whereas phospholipase A2 and phosph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55738cd56ddcbba5a8fe20305a361419
https://doi.org/10.1016/0020-711x(92)90038-3
https://doi.org/10.1016/0020-711x(92)90038-3
Publikováno v:
International Journal of Biochemistry. 23:689-693
1. The effects of age-dependent or liposome-induced alterations in the phospholipid composition of rat liver plasma and microsomal membranes on the phosphatidylethanolamine:ceramide-phosphoethanolamine (PE:Cer-PEt) and phosphatidylcholine:ceramide-ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f17504810f72bd40b82ac64784f867
https://doi.org/10.1016/0020-711x(91)90039-p
https://doi.org/10.1016/0020-711x(91)90039-p