Structural Insights of Shigella Translocator IpaB and Its Chaperone IpgC in Solution

Autor: Mariana L. Ferrari, Spyridoula N. Charova, Philippe J. Sansonetti, Efstratios Mylonas, Anastasia D. Gazi

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Bacterial Type III Secretion Systems (T3SSs) are specialized multicomponent nanomachines that mediate the transport of proteins either to extracellular locations or deliver Type III Secretion effectors directly into eukaryotic host cell cytoplasm. Sh

Externí odkaz: https://doaj.org/article/61c2fe45b44544b183075b725f47061f

Identification of novel substrates of Shigella T3SA through analysis of its virulence plasmid-encoded secretome.

Autor: Laurie Pinaud, Mariana L Ferrari, Robin Friedman, Nico Jehmlich, Martin von Bergen, Armelle Phalipon, Philippe J Sansonetti, François-Xavier Campbell-Valois

Publikováno v: PLoS ONE, Vol 12, Iss 10, p e0186920 (2017)

Many human Gram-negative bacterial pathogens express a Type Three Secretion Apparatus (T3SA), including among the most notorious Shigella spp., Salmonella enterica, Yersinia enterocolitica and enteropathogenic Escherichia coli (EPEC). These bacteria

Externí odkaz: https://doaj.org/article/5c49bd93812b423cad3bbc74b500a90e

Shigella promotes major alteration of gut epithelial physiology and tissue invasion by shutting off host intracellular transport

Autor: Philippe J. Sansonetti, Giulia Nigro, Alexandre Grassart, Guillaume Arras, Damarys Loew, Vanessa Masson, John R. Rohde, Valérie Malardé, Pamela Schnupf, Nathalie Sauvonnet, Stéphane Descorps-Declère, Mariana L. Ferrari, Laura Salavessa

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2019, ⟨10.1073/pnas.1902922116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, ⟨10.1073/pnas.1902922116⟩
Proceedings of the National Academy of Sciences

Intracellular trafficking pathways in eukaryotic cells are essential to maintain organelle identity and structure, and to regulate cell communication with its environment. Shigella flexneri invades and subverts the human colonic epithelium by the inj

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8eb1fcdbc53fbf24b660ca8d3fb08fc5
https://hal-pasteur.archives-ouvertes.fr/pasteur-02167942

Cellular and molecular biology of glycosphingolipid glycosylation

Autor: Hugo J F, Maccioni, Rodrigo, Quiroga, Mariana L, Ferrari

Publikováno v: Journal of neurochemistry. 117(4)

Brain tissue is characterized by its high glycosphingolipid content, particularly those containing sialic acid (gangliosides). As a result of this observation, brain tissue was a focus for studies leading to the characterization of the enzymes partic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ad2a6f32546ab46c2f69693c25c2d71
https://pubmed.ncbi.nlm.nih.gov/21371037

Calsenilin and CALP interact with the cytoplasmic tail of UDP-Gal:GA2/GM2/GD2 β-1,3-galactosyltransferase.

Autor: Cristián A. Quintero, Javier Valdez-taubas, Mariana L. Ferrari, Sergio D. Haedo, Hugo J. F. Maccioni

Publikováno v: Biochemical Journal; 2008, Vol. 412 Issue 1, p19-26, 8p