Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mariana K. Bormann"'
Identification of an Inherent Bioenergetic and Metabolic Phenotype in Late-Onset Alzheimer’s Disease
Publikováno v:
Biology and Life Sciences Forum, Vol 21, Iss 1, p 24 (2023)
The pathology of late-onset Alzheimer’s disease (LOAD) is still poorly understood, but it is multifactorial and closely related to changes with aging. We developed a cellular platform for collecting skin fibroblasts or blood cells from LOAD patient
Externí odkaz:
https://doaj.org/article/0f1357d97dd14594a036c601901c153a
Autor:
Woo‐In Ryu, Minqi Shen, Yoon Lee, Ryan A. Healy, Mariana K. Bormann, Bruce M. Cohen, Kai‐Christian Sonntag
Publikováno v:
Aging Cell. 21
The redox co-factor nicotinamide adenine dinucleotide (NAD) declines with age, and NAD deficits are specifically associated with dysfunctional energy metabolism in late-onset Alzheimer's disease (LOAD). Nicotinamide riboside (NR), a dietary NAD precu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863a297b8bce60a926836b6f7e2424c1
https://doi.org/10.1111/acel.13658
https://doi.org/10.1111/acel.13658
Autor:
Jisun So, Kai C. Sonntag, Minqi Shen, Woo-In Ryu, Bruce M. Cohen, Brent P. Forester, Hyemyung Seo, Mariana K Bormann, Yeongwon Park, Do Hoon Kim
Publikováno v:
Molecular Psychiatry
Altered energy metabolism has been implicated both in aging and the pathogenesis of late-onset Alzheimer’s disease (LOAD). However, it is unclear which anomalies are acquired phenotypes and which are inherent and predispose to disease. We report th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8c2e169caeb838c39eb4afb922137a
https://doi.org/10.1038/s41380-021-01068-3
https://doi.org/10.1038/s41380-021-01068-3