Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Mariana I. Nelson"'
Autor:
Ben J. Harrison, Nandita Bose, Xiaohong Qiu, Kyle S. Michel, Jeremy R. Graff, Richard Walsh, Mariana I. Nelson, Nadine R. Ottoson, Adria Jonas, Keith B. Gorden, Steven M. Leonardo, Michael E. Danielson, Kathleen E. Ertelt, Peter Maimonis, Anissa S.H. Chan, Myra L. Patchen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 11, p e0165909 (2016)
PLoS ONE, Vol 11, Iss 11, p e0165909 (2016)
Imprime PGG (Imprime), an intravenously-administered, soluble β-glucan, has shown compelling efficacy in multiple phase 2 clinical trials with tumor targeting or anti-angiogenic antibodies. Mechanistically, Imprime acts as pathogen-associated molecu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58209753cfca1dd1d9d1f444649633e
http://europepmc.org/articles/PMC5094785
http://europepmc.org/articles/PMC5094785
Publikováno v:
The Journal of Immunology. 189:4005-4013
The ability of the transmembrane adaptor protein linker for activation of T cells (LAT) to regulate T cell development, activation, survival, and homeostasis depends upon phosphorylation of its multiple tyrosine residues. The mutation of tyrosine 136
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0503649c2251e213551868173881823
https://doi.org/10.4049/jimmunol.1201380
https://doi.org/10.4049/jimmunol.1201380
Autor:
Richard Walsh, Kyle S. Michel, Nadine Ottoson, Yumi Yokoyama, Mary A. Antonysamy, Mariana I. Nelson, Michael E. Danielson, Mark N. Kirstein
Publikováno v:
Cancer Research. 73:B65-B65
Biothera is developing Imprime PGG® (Imprime PGG) for cancer that is synergistic with multiple anti-tumor monoclonal antibodies, demonstrating the potential to improve patient outcomes in a wide range of cancer indications. Although, the antitumor p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1f01927ae0c5c98314c9adb17acabf4
https://doi.org/10.1158/1538-7445.fbcr13-b65
https://doi.org/10.1158/1538-7445.fbcr13-b65