Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Mariana Gaya da Costa"'
Autor:
Eduardo Maia Martins Pereira, Tatiana Souza do Nascimento, Mariana Gaya da Costa, Eric Slawka, Carlos Galhardo Júnior
Publikováno v:
Brazilian Journal of Anesthesiology, Vol 74, Iss 5, Pp 844520- (2024)
Background: Midazolam is routinely used as preanesthetic medication in pediatric patients. Recently, dexmedetomidine has emerged as an alternative as a premedicant. We aimed to add more evidence about the efficacy and safety of two common routes of a
Externí odkaz:
https://doaj.org/article/3d214f3f2c4d40b4b2cba373b941a36c
Autor:
Felix Poppelaars, Siawosh K. Eskandari, Jeffrey Damman, Marc A. Seelen, Bernardo Faria, Mariana Gaya da Costa
Publikováno v:
Kidney Research and Clinical Practice, Vol 42, Iss 3, Pp 389-402 (2023)
Background Despite current matching efforts to identify optimal donor-recipient pairs for kidney transplantation, alloimmunity remains a major source of late transplant failure. Additional genetic parameters in donor-recipient matching could help imp
Externí odkaz:
https://doaj.org/article/b5072a1c6613454688746a46e0a30fa4
Autor:
Felix Poppelaars, Mariana Gaya da Costa, Siawosh K. Eskandari, Jeffrey Damman, Marc A. Seelen
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Rejection after kidney transplantation remains an important cause of allograft failure that markedly impacts morbidity. Cytokines are a major player in rejection, and we, therefore, explored the impact of interleukin-6 (IL6) and IL-6 recepto
Externí odkaz:
https://doaj.org/article/93961bfdfaa14ed48733f6d83499c6ae
Autor:
Bernardo Faria, Mariana Gaya da Costa, Felix Poppelaars, Casper F. M. Franssen, Manuel Pestana, Stefan P. Berger, Mohamed R. Daha, Carlo A. J. M. Gaillard, Marc A. Seelen
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Intravenous (IV) iron is widely used to treat anemia in chronic kidney disease patients. Previously, iron formulations were shown to induce immune activation in-vitro. The current study aimed to investigate the effect of IV iron on comple
Externí odkaz:
https://doaj.org/article/ec90782f091c4087a079b935839ff343
Autor:
Mariana Gaya da Costa, Felix Poppelaars, Cees van Kooten, Tom E. Mollnes, Francesco Tedesco, Reinhard Würzner, Leendert A. Trouw, Lennart Truedsson, Mohamed R. Daha, Anja Roos, Marc A. Seelen
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Introduction: The complement system is essential for an adequate immune response. Much attention has been given to the role of complement in disease. However, to better understand complement in pathology, it is crucial to first analyze this system un
Externí odkaz:
https://doaj.org/article/1e14a85316cb4fc29fd7b3fea599874e
Autor:
Felix Poppelaars, Mariana Gaya da Costa, Bernardo Faria, Stefan P. Berger, Solmaz Assa, Mohamed R. Daha, José Osmar Medina Pestana, Willem J. van Son, Casper F. M. Franssen, Marc A. Seelen
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Background: Hemodialysis (HD) is a life-saving treatment for patients with end stage renal disease. However, HD patients have markedly increased rates of cardiovascular morbidity and mortality. Previously, a link between the complement system and car
Externí odkaz:
https://doaj.org/article/2a55b90e353d4e32b9bf457e79e8b293
Autor:
Felix Poppelaars, Bernardo Faria, Mariana Gaya da Costa, Casper F. M. Franssen, Willem J. van Son, Stefan P. Berger, Mohamed R. Daha, Marc A. Seelen
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Significant advances have lead to a greater understanding of the role of the complement system within nephrology. The success of the first clinically approved complement inhibitor has created renewed appreciation of complement-targeting therapeutics.
Externí odkaz:
https://doaj.org/article/f44a5c9c38f64d0d824914418a8bd013
Autor:
Siawosh K. Eskandari, Mariana Gaya da Costa, Bernardo Faria, Vojtech Petr, Jamil R. Azzi, Stefan P. Berger, Marc A.J. Seelen, Jeffrey Damman, Felix Poppelaars
Publikováno v:
American Journal of Transplantation, 22(S4), 45-57. Wiley
American Journal of Transplantation, 22(S4), 45-57. Wiley-Blackwell Publishing Ltd
American Journal of Transplantation, 22(S4), 45-57. Wiley-Blackwell Publishing Ltd
Of all kidney transplants, half are still lost in the first decade after transplantation. Here, using genetics, we probed whether interleukin 6 (IL-6) could be a target in kidney transplantation to improve graft survival. Additionally, we investigate
Autor:
Felix Poppelaars, Siawosh K. Eskandari, Jeffrey Damman, Ashley Frazer-Abel, V. Michael Holers, Bradley P. Dixon, Mohamed R. Daha, Jan-Stephan F. Sanders, Marc A. Seelen, Bernardo Faria, Mariana Gaya da Costa, Joshua M. Thurman
IntroductionPlasma carboxypeptidase B2 (CPB2) is an enzyme that cleaves C-terminal amino acids from proteins, thereby regulating their activities. CPB2 has anti-inflammatory and anti-fibrinolytic properties and can therefore be protective or harmful
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::edc51d7193a8cba531f4475cc8703125
https://doi.org/10.1101/2023.05.08.23289675
https://doi.org/10.1101/2023.05.08.23289675
Autor:
Felix Poppelaars, Mariana Gaya da Costa, Bernardo Faria, Siawosh K Eskandari, Marc A Seelen, Jeffrey Damman
Publikováno v:
Journal of inflammation research, 15, 2243-2254. DOVE MEDICAL PRESS LTD
Journal of Inflammation Research, 15, 2243-2254. Dove Medical Press Ltd.
Journal of Inflammation Research, 15, 2243-2254. Dove Medical Press Ltd.
Felix Poppelaars,1 Mariana Gaya da Costa,1,2 Bernardo Faria,1,3 Siawosh K Eskandari,1 Marc A Seelen,1 Jeffrey Damman4 1Department of Internal Medicine, Division of Nephrology, University Medical Center Groningen, University of Groningen, Groningen, T