Výsledky vyhledávání - "Mariana F. C. Cardoso"

Tandem Synthesis of Furanaphthoquinones via Enamines and Evaluation of Their Antiparasitic Effects against Trypanosoma cruzi

Autor: Acácio S. de Souza, Vitor F. Ferreira, Mariana F. C. Cardoso, Ana Maria Caetano Faria, Robson Xavier Faria, Murilo Lamim Bello, Raíssa Maria Dos Santos Galvão, Luana da S. M. Forezi, Fernando Dias da Silva

Publikováno v: Journal of the Brazilian Chemical Society.

Furanaphthoquinones are well known in medicinal chemistry for exhibiting relevant structural heterogeneity and bioactivities. In this work, it was synthesized a series of furanaphthoquinones through a tandem reaction between lawsone (8) and cyclic ke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d387ac236d63d03614ffe9b34f4fff68
https://doi.org/10.21577/0103-5053.20210142

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Akademický článek

Carbene Transfer Reactions Catalysed by Dyes of the Metalloporphyrin Group

Autor: Mário M. Q. Simões, Daniel T. G. Gonzaga, Mariana F. C. Cardoso, Luana da S. M. Forezi, Ana T. P. C. Gomes, Fernando de C. da Silva, Vítor F. Ferreira, Maria G. P. M. S. Neves, José A. S. Cavaleiro

Publikováno v: Molecules, Vol 23, Iss 4, p 792 (2018)

Carbene transfer reactions are very important transformations in organic synthesis, allowing the generation of structurally challenging products by catalysed cyclopropanation, cyclopropenation, carbene C-H, N-H, O-H, S-H, and Si-H insertion, and olef

Externí odkaz: https://doaj.org/article/b23789625ead447f91625da6b6f471e4

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Screening of 1,2-furanonaphthoquinones 1,2,3-1H-triazoles for glycosidases inhibitory activity and free radical scavenging potential: an insight in anticancer activity

Autor: Vitor F. Ferreira, Fernando de C. da Silva, Rafael Ferreira Dantas, Mario Roberto Senger, Mariana F. C. Cardoso, Maria Cecília B. V. de Souza, Floriano P. Silva

Publikováno v: Medicinal Chemistry Research. 28:1579-1588

In many cancer cells, glycoproteins show abnormal glycosylation patterns which have been associated with tumor initiation, progression, and metastasis. Thus, the glycosidases involved in glycoprotein maturation represent good targets for the developm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::143d41fc7da3d2a7c5d314fbdfe9bd0d
https://doi.org/10.1007/s00044-019-02396-4

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Alternative Routes to the Click Method for the Synthesis of 1,2,3-Triazoles, an Important Heterocycle in Medicinal Chemistry

Autor: Vitor F. Ferreira, Daniel T. G. Gonzaga, Fernando de C. da Silva, Mariana F. C. Cardoso, Luana da S. M. Forezi

Publikováno v: Current Topics in Medicinal Chemistry. 18:1428-1453

Heterocyclic rings having nitrogen atoms are the molecular fragments most used in drug design by using the tools of medicinal chemistry. The 1,2,4-triazole rings are part of an extensive family of drugs that are in use in the pharmaceutical market. M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a93c340482255f5a79a0e628f7560e88
https://doi.org/10.2174/1568026618666180821143902

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Carbene-Type Species in the Functionalization of Porphyrin Derivatives

Autor: Ana T. P. C. Gomes, Vitor F. Ferreira, Mário M.Q. Simões, Mariana F. C. Cardoso, José A. S. Cavaleiro, Daniel T. G. Gonzaga, Luana da S. M. Forezi, Maria G. P. M. S. Neves, Fernando de C. da Silva

Publikováno v: Synthesis. 50:2678-2692

Carbenes and NHCs play an important role in porphyrin chemistry and several synthetically useful transformations leading to the preparation of new porphyrin derivatives have been developed. This short review presents an overview covering the literatu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcc70a3cec5513d61dc0ae2bbffe948a
https://doi.org/10.1055/s-0037-1609756

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Relationship between Electrochemical Parameters, Cytotoxicity Data against Cancer Cells of 3-Thio-Substituted Nor-Beta-Lapachone Derivatives. Implications for Cancer Therapy

Autor: Maria Francilene Souza Silva, Vitor F. Ferreira, Claudia Pessoa, Andre Felippe de Almeida Xavier, Yen G. de Paiva, Mariana F. C. Cardoso, Marília O. F. Goulart, Daniel Pascoalino Pinheiro, Fernando de C. da Silva, Thaissa L. Silva

Publikováno v: Journal of the Brazilian Chemical Society. 30

Electrochemical methods are powerful in the characterization and design of redox-modulating agents. We, herein, report the electrochemical investigation, in aprotic medium, of eleven synthetic 3-thio-substituted-nor-beta-lapachones, along with the de

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90c898a54be2a19473584542f40d075d
https://doi.org/10.21577/0103-5053.20180248

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Synthetic methodologies leading to porphyrin-quinone conjugates

Autor: Ângelo C. Pinto, Maria G. P. M. S. Neves, Mariana F. C. Cardoso, Luana da S. M. Forezi, José A. S. Cavaleiro, Vitor F. Ferreira, Fernando de C. da Silva

Publikováno v: Journal of Porphyrins and Phthalocyanines. 20:167-189

This review focuses on synthetic strategies that have been established for the preparation of porphyrin-quinone conjugates of potential biological significance and as donor–acceptor compounds for electron transfer processes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::44ba1b7218fb6488119643e4470946f4
https://doi.org/10.1142/s1088424616300093

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