Resveratrol encapsulation in high molecular weight chitosan-based nanogels for applications in ocular treatments: Impact on human ARPE-19 culture cells

Autor: Guadalupe Eugenia Garcia Liñares, Agustina Alaimo, Sofía L. Acebedo, Leonardo Lizarraga, Carla Cecilia Spagnuolo, Mariana Carolina Di Santo, Fernanda Elias, Karina Dafne Martínez, Mayra Alejandra Castañeda Cataña, Florencia Solana Buosi, Oscar E. Pérez

Publikováno v: International Journal of Biological Macromolecules. 165:804-821

Oxidative stress and inflammation play a pivotal role in ocular diseases. Resveratrol (RSV) is a natural bioactive that has recently attracted attention due to it potent antioxidant and anti-inflammatory properties. However, RSV presents poor aqueous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19486e587ddb39c815d9caff35436492
https://doi.org/10.1016/j.ijbiomac.2020.09.234

Biocompatibility analysis of high molecular weight chitosan obtained from Pleoticus muelleri shrimps. Evaluation in prokaryotic and eukaryotic cells

Autor: Regina De Matteo, Ana Paula Domínguez Rubio, Mariana Carolina Di Santo, Oscar E. Pérez, Agustina Alaimo

Publikováno v: Biochemistry and Biophysics Reports, Vol 24, Iss, Pp 100842-(2020)
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Biochemistry and Biophysics Reports

The search for the exploitation and recycling of biomaterials is increasing for reducing the use of non-renewable resources and minimizing environmental pollution caused by synthetic materials. In this context, Chitosan (CS) being a naturally occurri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f628a953e97b9811cdcd7fdb0042331e
http://www.sciencedirect.com/science/article/pii/S2405580820301527

Biological responses induced by high molecular weight chitosan administrated jointly with Platelet-derived Growth Factors in different mammalian cell lines

Autor: Sofía L. Acebedo, Oscar E. Pérez, Roberto Gabriel Pozner, Carla Cecilia Spagnuolo, Agustina Alaimo, Mariana Carolina Di Santo

Publikováno v: International journal of biological macromolecules. 158

In this work, we studied cellular responses known to be involved in tissue regeneration, such as proliferation, migration and tubulogenesis under High Molecular Weight Chitosan (HMWC) and recombinant Platelet-derived Growth Factor (PDGF) treatments u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fef03538e4d3fd6d3608d6cccf1007a5
https://pubmed.ncbi.nlm.nih.gov/32423872