CCL20 and Beta-Defensin 2 Production by Human Lung Epithelial Cells and Macrophages in Response to Brucella abortus Infection.

Autor: M Soledad Hielpos, Mariana C Ferrero, Andrea G Fernández, Josefina Bonetto, Guillermo H Giambartolomei, Carlos A Fossati, Pablo C Baldi

Publikováno v: PLoS ONE, Vol 10, Iss 10, p e0140408 (2015)

Both CCL20 and human β-defensin 2 (hBD2) interact with the same membrane receptor and display chemotactic and antimicrobial activities. They are produced by airway epithelia in response to infectious agents and proinflammatory cytokines. Whereas Bru

Externí odkaz: https://doaj.org/article/b012483961a34b379be93062bdd2434b

Immune Responses Potentially Involved in the Gestational Complications of Brucella Infection

Autor: Lucía Zavattieri, Florencia Muñoz González, Mariana C. Ferrero, Pablo C. Baldi

Publikováno v: Pathogens, Vol 12, Iss 12, p 1450 (2023)

Infection by Brucella species in pregnant animals and humans is associated with an increased risk of abortion, preterm birth, and transmission of the infection to the offspring. The pathogen has a marked tropism for the placenta and the pregnant uter

Externí odkaz: https://doaj.org/article/64a7c3673f3a45709eaa44f3e4025b92

Brucella abortus Proliferates in Decidualized and Non-Decidualized Human Endometrial Cells Inducing a Proinflammatory Response

Autor: Iván Mathias Alonso Paiva, Pablo C. Baldi, Mariana C. Ferrero, Andrea Canellada, Agustina Daniela Sotelo, Lucia Zavattieri

Publikováno v: Pathogens
Volume 9
Issue 5
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Pathogens, Vol 9, Iss 369, p 369 (2020)

Brucella spp. have been associated with abortion in humans and animals. Although the mechanisms involved are not well established, it is known that placental Brucella infection is accompanied by inflammatory phenomena. The ability of Brucella abortus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127e133091a698c8e06d6fa7c65e1a6a

Pathogenesis and immune response in Brucella infection acquired by the respiratory route

Autor: Mariana C. Ferrero, Pablo C. Baldi, Iván Mathias Alonso Paiva, Florencia Muñoz González

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Brucella infection is frequently acquired through the respiratory route. The pathogen disseminates systemically from the lungs to infect peripheral organs. In this review we summarize the existing data on the pathogenesis of inhalational Brucella inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6096b36767854cdbd8f15d57d0d007b8
https://pubmed.ncbi.nlm.nih.gov/32535086

Neutrophil Extracellular Traps Stimulate Proinflammatory Responses in Human Airway Epithelial Cells

Autor: Martín Rumbo, Leonardo Jairo Iula, Mariana C. Ferrero, Florencia Sabbione, Analía Silvina Trevani, Mirta Giordano, Irene Angélica Keitelman, Pablo C. Baldi, Carolina Jancic

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP

Tissue injury leads to the release of uric acid (UA). At high local concentrations, UA can form monosodium urate crystals (MSU). MSU and UA stimulate neutrophils to release extracellular traps (NET). Here, we investigated whether these NET could be i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79762e6a68fdb4eb10f5cf09983c4b07
https://doi.org/10.1159/000460293