Exploring the antifungal, antibiofilm and antienzymatic potential of Rottlerin in an in vitro and in vivo approach

Autor: Nagela Bernadelli Sousa Silva, Ralciane Paula Menezes, Daniela Silva Gonçalves, Mariana Brentini Santiago, Noemi Chagas Conejo, Sara Lemes Souza, Anna Lívia Oliveira Santos, Robinson Sabino da Silva, Salvador Boccaletti Ramos, Eloisa Amália Vieira Ferro, Carlos Henrique Gomes Martins

Publikováno v: Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)

Abstract Candida species have been responsible for a high number of invasive infections worldwide. In this sense, Rottlerin has demonstrated a wide range of pharmacological activities. Therefore, this study aimed to evaluate the antifungal, antibiofi

Externí odkaz: https://doaj.org/article/94a3e520b64348f7b40b8e31af0995c4

Potential in vitro anti-periodontopathogenic, anti-Chikungunya activities and in vivo toxicity of Brazilian red propolis

Autor: Nagela Bernadelli Sousa Silva, Jonathan Henrique de Souza, Mariana Brentini Santiago, Jhennyfer Rodrigues da Silva Aguiar, Daniel Oliveira Silva Martins, Rafael Alves da Silva, Igor de Andrade Santos, Jennyfer A. Aldana-Mejía, Ana Carolina Gomes Jardim, Reginaldo dos Santos Pedroso, Sergio Ricardo Ambrósio, Rodrigo Cássio Sola Veneziani, Jairo Kenupp Bastos, Regina Helena Pires, Carlos Henrique Gomes Martins

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)

Abstract Bacterial and viral infections are serious public health issue. Therefore, this study aimed to evaluate the antibacterial, antibiofilm and antiviral potential of the Brazilian Red Propolis (BRP) crude hydroalcoholic extract, fractions, and i

Externí odkaz: https://doaj.org/article/a11e82e7c64e437996f2b5e957921a16

Antifungal Activities of Essential Oils from Protium ovatum Engl. Against Malassezia furfur and Candida Species

Autor: Gardênia Barbosa Carrijo Rodrigues, Cassia Cristina Fernandes, Suzana Maria Loures de Oliveira Marcionilio, Vitor de Paula Castro, Carmen Magaly Alvarez, Regina Helena Pires, Mariana Brentini Santiago, Reginaldo dos Santos Pedroso, Carlos Henrique Gomes Martins, Mayker

Publikováno v: Orbital: The Electronic Journal of Chemistry, Vol 14, Iss 3 (2022)

Fungal opportunistic infections have increased in recent decades due to the increase in the immunosuppressed patients and the indiscriminate use of antifungals. In Brazil, a country with the greatest biodiversity in the world, studies that seek new a

Externí odkaz: https://doaj.org/article/edcc45f30c644a4d916d15aea27fbcc4

Assessment of the antibacterial, antivirulence, and action mechanism of Copaifera pubiflora oleoresin and isolated compounds against oral bacteria

Autor: Thaís da Silva Moraes, Luis Fernando Leandro, Mariana Brentini Santiago, Larissa de Oliveira Silva, Thamires Chiquini Bianchi, Rodrigo Cássio Sola Veneziani, Sérgio Ricardo Ambrósio, Salvador Boccaletti Ramos, Jairo Kenupp Bastos, Carlos Henrique Gomes Martins

Publikováno v: Biomedicine & Pharmacotherapy, Vol 129, Iss , Pp 110467- (2020)

The microorganisms that constitute the oral microbiome can cause oral diseases, including dental caries and endodontic infections. The use of natural products could help to overcome bacterial resistance to the antimicrobials that are currently employ

Externí odkaz: https://doaj.org/article/e5112e0ff75848c9b609ef52ee7e7263

Antifungal and antioxidant activities and chemical constituents from Pluchea sagittalis

Autor: Leonardo da Silva Freitas, Wdislaine Pinheiro de Andrade, Diandra Nunes Barreto, Tiara da Costa Silva, Mariana Brentini Santiago, Mário Machado Martins, Mychelle Carvalho, Daniel Pena Pereira, Robson Thomaz Thuler, Carlos Henrique Gomes Martins, Victor Peçanha de Miranda Coelho, Luís Carlos Scalon Cunha

Publikováno v: Research, Society and Development; Vol. 11 No. 7; e40111730059
Research, Society and Development; Vol. 11 Núm. 7; e40111730059
Research, Society and Development; v. 11 n. 7; e40111730059
Research, Society and Development
Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI

Pluchea sagittalis (Asteraceae) is widely distributed in South America and used as a medicinal plant to treat various diseases. The objectives of the work were to evaluate the antioxidant and antifungal activities of the ethanol extract and fractions

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::058a2f3394cfe0b2a63abd3975275565
https://rsdjournal.org/index.php/rsd/article/view/30059