Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mariana Bollo"'
Autor:
Carolina Morales, Macarena Fernandez, Rodrigo Ferrer, Daniel Raimunda, Dolores C. Carrer, Mariana Bollo
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 8, p 7209 (2023)
The Unfolded protein response (UPR), triggered by stress in the endoplasmic reticulum (ER), is a key driver of neurodegenerative diseases. GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff disease, is caused by an accumulation of GM2, mainly
Externí odkaz:
https://doaj.org/article/64ac95e5202c41dc8507b620b19c0ff9
Publikováno v:
Neurobiology of Disease, Vol 94, Iss , Pp 139-156 (2016)
The Ca2+-dependent phosphatase, calcineurin (CN) is thought to play a detrimental role in damaged neurons; however, its role in astrocytes is unclear. In cultured astrocytes, CNβ expression increased after treatment with a sarco/endoplasmic reticulu
Externí odkaz:
https://doaj.org/article/27b59fdd071f4f2fb1bfc9ac6ec3d9ee
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
17β-estradiol (E2) induces axonal growth through extracellular signal-regulated kinase 1 and 2 (ERK1/2)-MAPK cascade in hypothalamic neurons of male rat embryos in vitro, but the mechanism that initiates these events is poorly understood. This study
Externí odkaz:
https://doaj.org/article/70617abb25df427b8760c23aac4718dc
Autor:
Mariana Bollo, R Madelaine Paredes, Deborah Holstein, Nadezhda Zheleznova, Patricia Camacho, James D Lechleiter
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e11925 (2010)
The accumulation of misfolded proteins within the endoplasmic reticulum (ER) triggers a cellular process known as the Unfolded Protein Response (UPR). One of the earliest responses is the attenuation of protein translation. Little is known about the
Externí odkaz:
https://doaj.org/article/e0d55b7d22e64f2a891e9a637f0df303
Autor:
Constanza Feliziani, Macarena Fernandez, Gonzalo Quassollo, Deborah Holstein, Sebastián M Bairo, James C Paton, Adrienne W Paton, Juan de Batista, James D Lechleiter, Mariana Bollo
Publikováno v:
Cell Calcium
The accumulation of unfolded proteins within the Endoplasmic Reticulum (ER) activates a signal transduction pathway termed the unfolded protein response (UPR), which attempts to restore ER homeostasis. If this cannot be done, UPR signalling ultimatel
Publikováno v:
Journal of Visualized Experiments.
The accumulation of unfolded proteins within the endoplasmic reticulum (ER), caused by any stress condition, triggers the unfolded protein response (UPR) through the activation of specialized sensors. UPR attempts first to restore homeostasis; but if
Autor:
María José Virgolini, Pablo H.H. Lopez, Constanza Feliziani, Mariana Bollo, María Julia Cambiasso
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1866:225-239
GM2-gangliosidosis, a subgroup of lysosomal storage disorders, is caused by deficiency of hexosaminidase activity, and comprises the closely related Tay-Sachs and Sandhoff diseases. The enzyme deficiency prevents normal metabolization of ganglioside
Autor:
Adrienne W. Paton, James C. Paton, Macarena Fernadez, Gonzalo Quassollo, James D. Lechleiter, Constanza Feliziani, Deborah M. Holstein, Mariana Bollo
The accumulation of unfolded proteins within the Endoplasmic Reticulum (ER) activates a signal transduction pathway termed theunfoldedprotein response (UPR), which attempts to restore ER homeostasis. If homeostasis cannot be restored, UPR signalling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6316ffeda5b6a40aeea796cd7f4e78b
https://doi.org/10.1101/2020.10.07.328849
https://doi.org/10.1101/2020.10.07.328849
Autor:
Arlan Richardson, Janice Jianhong Deng, Yidong Bai, Mariana Bollo, James D. Lechleiter, Da Ting Lin, Julie C. Etzler, Deborah M. Holstein, Viviana I. Pérez
Cyclophilin D (CyPD), a mitochondrial matrix protein, has been widely studied for its role in mitochondrial-mediated cell death. Unexpectedly, we previously discovered that overexpression of CyPD in a stable cell line, increased mitochondrial membran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::381a96eced92bd62a98cbbc86105afa4
https://linkinghub.elsevier.com/retrieve/pii/S0003986116305240
https://linkinghub.elsevier.com/retrieve/pii/S0003986116305240
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neurobiology of disease
Neurobiology of Disease, Vol 94, Iss, Pp 139-156 (2016)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Neurobiology of disease
Neurobiology of Disease, Vol 94, Iss, Pp 139-156 (2016)
The Ca2 +-dependent phosphatase, calcineurin (CN) is thought to play a detrimental role in damaged neurons; however, its role in astrocytes is unclear. In cultured astrocytes, CNβ expression increased after treatment with a sarco/endoplasmic reticul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d622c3c144b2ab7d6f3e1f03759b7d0c
http://www.sciencedirect.com/science/article/pii/S0969996116301449
http://www.sciencedirect.com/science/article/pii/S0969996116301449