Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Mariana, Pinteala"'
Autor:
Denisse-Iulia Bostiog, Natalia Simionescu, Adina Coroaba, Ioana C. Marinas, Mariana C. Chifiriuc, Gratiela Gradisteanu Pircalabioru, Stelian S. Maier, Mariana Pinteala
Publikováno v:
Drug Delivery, Vol 31, Iss 1 (2024)
Methotrexate (MTX) is a folic acid antagonist routinely used in cancer treatment, characterized by poor water solubility and low skin permeability. These issues could be mitigated by using drug delivery systems, such as functionalized gold nanopartic
Externí odkaz:
https://doaj.org/article/b7855c1900d84980854cbc373f538aa5
Autor:
Zohra Bouchekhou, Amel Hadj Ziane-Zafour, Florentina Geanina Lupascu, Bianca-Ștefania Profire, Alina Nicolescu, Denisse-Iulia Bostiog, Florica Doroftei, Ioan-Andrei Dascalu, Cristian-Dragoș Varganici, Mariana Pinteala, Lenuta Profire, Tudor Pinteala, Bachir Bouzid
Publikováno v:
Pharmaceutics, Vol 16, Iss 9, p 1190 (2024)
Although niflumic acid (NA) is one of the most used non-steroidal anti-inflammatory drugs, it suffers from poor solubility, low bioavailability, and significant adverse effects. To address these limitations, the complexation of NA with cyclodextrins
Externí odkaz:
https://doaj.org/article/5a70e5b738964a45bc02d267ba1e249b
Autor:
Ioana C. Marinas, Leonard Ignat, Ignat E. Maurușa, Madalina D. Gaboreanu, Coroabă Adina, Marcela Popa, Mariana C. Chifiriuc, Marian Angheloiu, Mihaela Georgescu, Alexandra Iacobescu, Gratiela Gradisteanu Pircalabioru, Miruna Stan, Mariana Pinteala
Publikováno v:
Heliyon, Vol 10, Iss 4, Pp e26047- (2024)
Chronic wounds represent one of the complications that might occur from the disruption of wound healing process. Recently, there has been a rise in interest in employing nanotechnology to develop novel strategies for accelerating wound healing. The a
Externí odkaz:
https://doaj.org/article/8e5badffa8c94599badd9d60e62d66ad
Autor:
Geanina Voicu, Cristina Ana Mocanu, Florentina Safciuc, Maria Anghelache, Mariana Deleanu, Sergiu Cecoltan, Mariana Pinteala, Cristina Mariana Uritu, Ionel Droc, Maya Simionescu, Ileana Manduteanu, Manuela Calin
Publikováno v:
Materials Today Bio, Vol 20, Iss , Pp 100620- (2023)
Runx2 is a key transcription factor involved in valvular interstitial cells (VIC) osteodifferentiation, a process actively entwined with the calcific aortic valve disease (CAVD). We hypothesize that a strategy intended to silence Runx2 could be a val
Externí odkaz:
https://doaj.org/article/53f5761dc0514927ade14d308f53a6ed
Publikováno v:
Molecules, Vol 29, Iss 1, p 28 (2023)
The superior properties of electrodeposited trimetallic CuZnCo nanoparticles, arising from the synergistic effect of combining the unique features of metallic components, were confirmed using voltametric measurements. The surface morphology and struc
Externí odkaz:
https://doaj.org/article/bf3a55fd8f2b4080b6ba3359f5d3cb20
Autor:
Ioana Mirela Vasincu, Maria Apotrosoaei, Florentina Lupascu, Andreea-Teodora Iacob, Simona-Eliza Giusca, Irina-Draga Caruntu, Narcisa-Laura Marangoci, Anca Roxana Petrovici, Gabriela Dumitrita Stanciu, Bogdan-Ionel Tamba, Bianca-Stefania Profire, Alin-Viorel Focsa, Mariana Pinteala, Lenuta Profire
Publikováno v:
Pharmaceutics, Vol 15, Iss 10, p 2492 (2023)
Generally, NSAIDs are weakly soluble in water and contain both hydrophilic and hydrophobic groups. One of the most widely used NSAIDs is ibuprofen, which has a poor solubility and high permeability profile. By creating dynamic, non-covalent, water-so
Externí odkaz:
https://doaj.org/article/41f03abcc9ed449582e6c7ad6a7fd350
Autor:
Adeline Josephine Cumpata, Dragos Peptanariu, Ana-Lacramioara Lungoci, Luminita Labusca, Mariana Pinteala, Luminita Radulescu
Publikováno v:
Medicina, Vol 59, Iss 3, p 587 (2023)
Introduction and Background: Based on stem cells, bioactive molecules and supportive structures, regenerative medicine (RM) is promising for its potential impact on field of hearing loss by offering innovative solutions for hair cell rescue. Nanotech
Externí odkaz:
https://doaj.org/article/3251868b3a47481b9b027000b73728bc
Autor:
Monica-Cornelia Sardaru, Anda Mihaela Craciun, Cristina-Maria Al Matarneh, Isabela Andreea Sandu, Roxana Maria Amarandi, Lacramioara Popovici, Catalina Ionica Ciobanu, Dragos Peptanariu, Mariana Pinteala, Ionel I. Mangalagiu, Ramona Danac
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 35, Iss 1, Pp 1581-1595 (2020)
A potential microtubule destabilising series of new indolizine derivatives was synthesised and tested for their anticancer activity against a panel of 60 human cancer cell lines. Compounds 11a, 11b, 15a, and 15j showed a broad spectrum of growth inhi
Externí odkaz:
https://doaj.org/article/991624767b6e4e398dd822986eb52e4d
Publikováno v:
Molecules, Vol 28, Iss 3, p 1086 (2023)
Dextran is by far one of the most interesting non-toxic, bio-compatible macromolecules, an exopolysaccharide biosynthesized by lactic acid bacteria. It has been extensively used as a major component in many types of drug-delivery systems (DDS), which
Externí odkaz:
https://doaj.org/article/ecf55a5b357c4cae93d1e60b1f822935
Autor:
Andrea Angeli, Mariana Pinteala, Stelian S. Maier, Sonia Del Prete, Clemente Capasso, Bogdan C. Simionescu, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 34, Iss 1, Pp 244-249 (2019)
A series of benzenesulfonamides incorporating selenazoles with diverse substitution patterns were investigated as inhibitors of six bacterial carbonic anhydrases (CAs, EC 4.2.1.1) from bacterial pathogens, such as Helicobacter pylori (hpCAα was the
Externí odkaz:
https://doaj.org/article/c2724a019533404f899abec29e79991d