Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Mariana, Hildesheim"'
Autor:
Victor R. Gordeuk, Roberto Machado, Gregory J. Kato, Mariana Hildesheim, Jane A. Little, Mehdi Nouraie, Mark T. Gladwin, Solomon Johnson, J. Simon R. Gibbs
Publikováno v:
Am J Hematol
The six-minute walk test (6MWT) has been used in patients with sickle cell disease (SCD), in conjunction with tricuspid regurgitant velocity (TRV) and plasma N-terminal pro-brain natriuretic peptide (NT-pro BNP), to assess risk of having pulmonary hy
Autor:
Enrico M Novelli, Mariana Hildesheim, Caterina Rosano, Rebecca Vanderpool, Marc Simon, Gregory J Kato, Mark T Gladwin
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114309 (2014)
A seeming paradox of sickle cell disease is that patients do not suffer from a high prevalence of systemic hypertension in spite of endothelial dysfunction, chronic inflammation and vasculopathy. However, some patients do develop systolic hypertensio
Externí odkaz:
https://doaj.org/article/1794b98d6eb64d5fba629bf332d12f07
Autor:
Mark T Gladwin, Robyn J Barst, J Simon R Gibbs, Mariana Hildesheim, Vandana Sachdev, Mehdi Nouraie, Kathryn L Hassell, Jane A Little, Dean E Schraufnagel, Lakshmanan Krishnamurti, Enrico Novelli, Reda E Girgis, Claudia R Morris, Erika Berman Rosenzweig, David B Badesch, Sophie Lanzkron, Oswaldo L Castro, James G Taylor, Jonathan C Goldsmith, Gregory J Kato, Victor R Gordeuk, Roberto F Machado, walk-PHaSST Investigators and Patients
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e99489 (2014)
The role of pulmonary hypertension as a cause of mortality in sickle cell disease (SCD) is controversial.We evaluated the relationship between an elevated estimated pulmonary artery systolic pressure and mortality in patients with SCD. We followed pa
Externí odkaz:
https://doaj.org/article/36ede0ae221943d1887a84c560bea8cc
Autor:
Deepika S Darbari, Zhengyuan Wang, Minjung Kwak, Mariana Hildesheim, James Nichols, Darlene Allen, Catherine Seamon, Marlene Peters-Lawrence, Anna Conrey, Mary K Hall, Gregory J Kato, James G Taylor
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79923 (2013)
Frequent painful vaso-occlusive crises (VOCs) were associated with mortality in the Cooperative Study of Sickle Cell Disease (CSSCD) over twenty years ago. Modern therapies for sickle cell anemia (SCA) like hydroxyurea are believed to have improved o
Externí odkaz:
https://doaj.org/article/47cfeb83c7514bb59e15ffefd67f7b5e
Autor:
Mariana Hildesheim, Stuart W. Krasner, Kenneth P. Cantor, Peter J. Weyer, Mary H. Ward, Charles F. Lynch, Rena R. Jones, Gary L. Amy, L.E. Beane Freeman
Publikováno v:
ISEE Conference Abstracts. 2020
Autor:
Roberto Machado, Solomon Johnson, Mariana Hildesheim, Victor R. Gordeuk, Mark T. Gladwin, Seyed Mehdi Nouraie, Jane A. Little, Gregory J. Kato, J. Simon R. Gibbs
Publikováno v:
Blood. 136:59-60
The six-minute walk test (6MWT) is a well-established assessment of the cardiopulmonary function of sickle cell disease (SCD) patients. The test is used for people with SCD who are suspected of having hypoxia or an elevated estimated pulmonary arteri
Autor:
Gregory J. Kato, J. Simon R. Gibbs, Jane A. Little, Victor R. Gordeuk, Mehdi Nouraie, Claudia R. Morris, Mariana Hildesheim, Mark T. Gladwin, Roberto Machado
Publikováno v:
Am J Hematol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea922069b7b11aba66199eaf52a3255f
https://europepmc.org/articles/PMC7194466/
https://europepmc.org/articles/PMC7194466/
Autor:
Gregory J. Kato, Netanya G. Sandler, Christopher Koh, T. Shields, Mark T. Gladwin, Jay H. Hoofnagle, David E. Kleiner, James G. Taylor, Daniel C. Douek, Jordan J. Feld, James S. Nichols, Theo Heller, T. Jake Liang, Mariana Hildesheim, V. Haynes-Williams
Publikováno v:
Alimentary Pharmacology & Therapeutics. 42:912-921
Summary Background Increased life expectancy in sickle cell disease (SCD) has resulted in greater recognition of the consequences of repeated intravascular vaso-occlusion and chronic haemolysis to multiple organ systems. Aim To report the long-term c
Publikováno v:
Pediatric Blood & Cancer. 61:1068-1073
Background Poor hydroxyurea (HU) adherence limits effective HU use in patients with sickle cell disease (SCD). Electronic directly observed therapy (DOT) may limit costs and achieve high HU adherence in children with SCD. This study aimed to determin
Autor:
Gregory J. Kato, Margaret V. Ragni, Michael P. Meyer, Victor R. Gordeuk, Yingze Zhang, Andrea L. Cortese Hassett, Mark T. Gladwin, Mariana Hildesheim, Jeffrey S. Isenberg, Suchitra Barge, Enrico M. Novelli, Mehdi Nouraie
Publikováno v:
American Journal of Hematology. 87:326-330
Platelets are activated in sickle cell disease (SCD), and particularly during vaso-occlusive episodes (VOE). Thrombospondin-1 (TSP1), a major secretory product of activated platelets, is increased in the circulation in VOE and binds to sickle red blo