Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Marian Wielosz"'
Publikováno v:
Current Issues in Pharmacy and Medical Sciences, Vol 28, Iss 4, Pp 264-268 (2015)
The effectiveness of lithium in the treatment of affective disorders is well documented. However, the mechanism of this effect is still unknown. The purpose of this study was to investigate the effect of lithium on serotonergic neurons. The evaluatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::550b2e57e4dade612f5c8e4c0c229817
https://doi.org/10.1515/cipms-2015-0086
https://doi.org/10.1515/cipms-2015-0086
Autor:
Tomasz Mróz, Jarogniew J. Łuszczki, Piotr Tutka, Marian Wielosz, Roman Mądro, Krzysztof Bańka, Krzysztof Tutaj, Grzegorz Buszewicz, Bartłomiej Barczyński
Publikováno v:
European Journal of Pharmacology. 650:550-555
Experimental evidence indicates that bupropion hydrochloride, an antidepressant and a first-line smoking cessation aid, exerts dose-dependently anticonvulsant and convulsant effects. In this study, chronic bupropion pretreatment intraperitoneally (i.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49646a01c6767363ff5c5c1cb38e5ad7
https://doi.org/10.1016/j.ejphar.2010.10.039
https://doi.org/10.1016/j.ejphar.2010.10.039
Publikováno v:
Neuroscience Letters. 435:169-173
We describe a novel aspect of action of memantine ex vivo, in the brain cortical slices and in vitro, in mixed glial cultures. The drug potently increased the production of kynurenic acid, an endogenous tryptophan metabolite blocking N-methyl-D-aspar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f77931b24494a0eac63bdc674a09b69
https://doi.org/10.1016/j.neulet.2008.02.027
https://doi.org/10.1016/j.neulet.2008.02.027
Publikováno v:
Epilepsy Research. 64:13-22
Bupropion, a unique, non-nicotine smoking cessation aid and an effective antidepressant, is well known to produce seizures following overdosing in humans. However, the experimental background for the usefulness of antiepileptic drugs in the protectio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dd2da05107674caee40cb742d2eed9
https://doi.org/10.1016/j.eplepsyres.2005.01.006
https://doi.org/10.1016/j.eplepsyres.2005.01.006
Autor:
Jerzy W. Lazarewicz, R. Paczek, Apolonia Ziembowicz, Tomasz Kocki, Ewa M. Urbańska, Elzbieta Luchowska, Piotr Luchowski, Waldemar A. Turski, Marian Wielosz
Publikováno v:
Journal of Neuroscience Research. 79:375-382
Increased serum level of homocysteine, a sulfur-containing amino acid, is considered a risk factor in vascular disorders and in dementias. The effect of homocysteine and metabolically related compounds on brain production of kynurenic acid (KYNA), an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46da45e59e9943380f83970ecaf11a93
https://doi.org/10.1002/jnr.20359
https://doi.org/10.1002/jnr.20359
Publikováno v:
European Neuropsychopharmacology. 15:85-93
The role of adenosine A1 receptors in the activity of drugs and substances protecting against seizures evoked by mitochondrial toxin, 3-nitropropionic acid (3-NPA) was studied in mice. Non-selective A1/A2 adenosine receptor antagonist, aminophylline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d88a9b3681ecfbacaff137674e83eba
https://doi.org/10.1016/j.euroneuro.2004.05.006
https://doi.org/10.1016/j.euroneuro.2004.05.006
Publikováno v:
European Neuropsychopharmacology. 14:307-318
Experimental studies have indicated that the central histaminergic system plays an important role in the inhibition of seizures through the stimulation of histamine H 1 receptors. H 1 receptor antagonists, including classical antiallergic drugs, occa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b22a8692d4aa11cd23721185c4fe84a7
https://doi.org/10.1016/j.euroneuro.2003.09.005
https://doi.org/10.1016/j.euroneuro.2003.09.005
Publikováno v:
Journal of Neural Transmission. 109:455-466
Molsidomine (25 mg kg(-1)), a donor of nitric oxide, commonly used in the treatment of coronary artery disease, enhanced the protective activity of valproate against the clonic phase of pentylenetetrazole-induced seizures in mice, significantly reduc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc9b680bc3d5a5922928ddf5f48de8c6
https://doi.org/10.1007/s007020200037
https://doi.org/10.1007/s007020200037
Autor:
Marian Wielosz, Stanisław J. Czuczwar, Zdzisław Kleinrok, Dorota Żółkowska, Małgorzata Młynarczyk, Piotr Tutka
Publikováno v:
European Journal of Pharmacology. 437:47-53
We studied whether N G -nitro- l -arginine (NNA), an inhibitor of nitric oxide (NO) synthase as well as l -arginine and molsidomine, two agents elevating NO, influenced convulsions caused by 4-aminopyridine, a K + channel blocker in mice. NNA, in a d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93a15c14dcdffa9d953059b7f712103d
https://doi.org/10.1016/s0014-2999(01)01600-4
https://doi.org/10.1016/s0014-2999(01)01600-4
Publikováno v:
European Journal of Pharmacology. 431:209-214
In this study, we evaluated whether beta-adrenoceptor antagonists may modify the protective efficacy of dizocilpine (MK-801), a NMDA receptor antagonist, and 1-(4-aminophenyl)-4-methyl-7,8-methylenedioxy-5H-2,3-benzodiazepine (GYKI 52466), a non-NMDA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba6f7f704babaf028ba746d16ceb4dc
https://doi.org/10.1016/s0014-2999(01)01452-2
https://doi.org/10.1016/s0014-2999(01)01452-2