Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Marian W. Fischman"'
Autor:
Anissa Abi-Dargham, Allegra Broft, Rajesh Narendran, Marian W. Fischman, Audrey Perez, Dah-Ren Hwang, Mark Slifstein, Herbert D. Kleber, Marc Laruelle, Richard W. Foltin, Diana Martinez
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Objective The goal of this study was to determine D1 receptor availability in human cocaine dependent (CD) subjects and matched healthy controls (HC). In addition, the cocaine dependent subjects performed cocaine self-administration sessions in order
Autor:
Marian W. Fischman, Charles P. O'Brien, Abeer M. Al-Ghananeem, Karen Miotto, Walter Ling, Herbert D. Kleber, Elmer Yu, Evaristo Akerele, Ahmed Elkashef, Barbara H Herman
Publikováno v:
The American Journal of Drug and Alcohol Abuse. 34:611-616
Objectives: The objective of this investigation was to characterize the pharmacokinetic profile of lofexidine. Lofexidine is an orally bioavailable α 2-adrenergic receptor agonist analogue of clonidine that acts centrally to suppress opiate withdraw
Autor:
Carl L. Hart, Marian W. Fischman, Sandra D. Comer, Margaret Haney, Richard W. Foltin, Amie S. Ward
Publikováno v:
Psychopharmacology. 164:407-415
Rationale. Although smoked marijuana contains at least 60 cannabinoids, Δ9-tetrahydrocannabinol (Δ9-THC) is presumed to be the cannabinoid primarily responsible for many marijuana-related effects, including increased food intake and subjective effe
Publikováno v:
Psychopharmacology. 164:376-384
Rationale. The discriminative stimulus effects of N-methyl-D-aspartate (NMDA) antagonists have been assessed in laboratory animals. To date, no published study has assessed their ability to alter methamphetamine-related discriminative stimulus effect
Publikováno v:
Drug and Alcohol Dependence. 67:301-309
Studies have shown that the Delta(9)-tetrahydrocannabinol (Delta(9)-THC) concentration in marijuana cigarettes is an important factor for the maintenance of marijuana self-administration. Yet, the impact of oral Delta(9)-THC treatment on marijuana se
Autor:
Eric D. Collins, Herbert D. Kleber, Elie S. Nuwayser, Sandra D. Comer, James H. Kerrigan, Marian W. Fischman
Publikováno v:
Psychopharmacology. 159:351-360
Rationale: Naltrexone, an opioid antagonist, is currently approved as a treatment for heroin dependence. However, naltrexone is generally not well accepted by patients, and medication non-compliance is a difficult obstacle to treatment. A sustained-r
Publikováno v:
Neuropsychopharmacology. 25:757-765
Although the ability to perform complex cognitive operations is assumed to be impaired following acute marijuana smoking, complex cognitive performance after acute marijuana use has not been adequately assessed under experimental conditions. In the p
Publikováno v:
Psychopharmacology. 155:330-337
Rationale: Data obtained in laboratory animals and humans suggest that dopamine D1 receptor antagonists decrease cocaine self-administration and block cocaine's discriminative stimulus and subjective effects. Objectives: This study investigates the e
Autor:
Richard W. Foltin, Marian W. Fischman, Sandra D. Comer, Carl L. Hart, Amie S. Ward, Margaret Haney
Publikováno v:
Psychopharmacology. 155:397-404
Rationale: Although methamphetamine use has increased over the past several years, few studies have evaluated the effects of repeated methamphetamine administration in humans. Objectives: Because methamphetamine is often taken in a pattern of repeate
Autor:
Margaret Haney, Marian W. Fischman, Amie S. Ward, Carl L. Hart, Richard W. Foltin, Sandra D. Comer
Publikováno v:
Psychopharmacology. 155:171-179
Rationale: Symptoms of withdrawal after daily marijuana smoking include increased ratings of irritability and depression. Similar mood symptoms are reported by cigarette smokers during nicotine abstinence. Objective: Given the successful use of susta