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Autor:
Mari Savolainen, T. Petteri Piepponen, Jaakko Kopra, Michael F. Salvatore, Saara Rannanpää, Jaan-Olle Andressoo, Timo T. Myöhänen, Marian Villarta-Aguilera, Samo Weingerl
Publikováno v:
Neuropharmacology. 128:221-230
Addictive drugs enhance dopamine release in the striatum, which can lead to compulsive drug-seeking after repeated exposure. Glial cell line-derived neurotrophic factor (GDNF) is an important regulator of midbrain dopamine neurons, and may play a mec