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Autor:
Rochelle F. McAdam, Vijay Ramaswamy, Xuejun Li, Marian Sia, Michael D. Taylor, Xin Chen, Hyun-Kee Min, Michelle A Francisco, Ali Momin, Siyi Wanggou, Weifan Dong, Ronwell J. Pusong, Shixuan Liu, Noriyuki Kijima, Xi Huang, Jerry J. Fan, Namal Abeysundara, Jade Chan, Yuanquan Song, Lu-Yang Wang, Ran Kafri, Nish Patel
Publikováno v:
The Journal of Experimental Medicine
Francisco et al. show that chloride intracellular channel 1 (CLIC1) is an evolutionarily conserved regulator of brain tumor growth in Drosophila and medulloblastoma mouse models. CLIC1 cooperates with potassium channels to regulate cell volume homeos