Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Marian Raschke"'
Autor:
Alexandros Vakalopoulos, Frank Wunder, Ingo V. Hartung, Gorden Redlich, Rolf Jautelat, Philipp Buchgraber, Jorma Hassfeld, Alexey V. Gromov, Niels Lindner, Donald Bierer, Jörg Gries, Walter Kroh, Holger Paulsen, Joachim Mittendorf, Dieter Lang, Eva Becker-Pelster, Damian Brockschnieder, Volker Geiss, Volkhart Li, Alexander Straub, Andreas Knorr, Thomas Mondritzki, Hubert Trübel, Marian Raschke, Martina Schaefer, Dirk Thomas, Peter Sandner, Johannes-Peter Stasch, Markus Follmann
Publikováno v:
Journal of Medicinal Chemistry.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73f98e7d872f77068d8ae9eeaa915fa4
https://doi.org/10.1021/acs.jmedchem.2c02082
https://doi.org/10.1021/acs.jmedchem.2c02082
Autor:
Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner
Effect of BAY 1217389 in monotherapy and combination therapy with paclitaxel on total KNL1 in A2780Cis tumors in nude mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf0b68fc1d8f214b0b3e08ca88297410
https://doi.org/10.1158/1535-7163.22508437.v1
https://doi.org/10.1158/1535-7163.22508437.v1
Autor:
Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner
Multinuclearity in U2OS cells induced by Mps1 inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2921d9472516e80123b05471c837506f
https://doi.org/10.1158/1535-7163.22508449.v1
https://doi.org/10.1158/1535-7163.22508449.v1
Autor:
Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner
H&E stained A2780cis tumors after treatment with vehicle paclitaxel alone BAY 1161909 alone or in combination with BAY 1161909 and paclitaxel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9c126cf3b030f5383bcf8d4111e2f2
https://doi.org/10.1158/1535-7163.22508446.v1
https://doi.org/10.1158/1535-7163.22508446.v1
Autor:
Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner
Additional data showing pharmacological characterization of Mps1 Inhibitors BAY 1161909 and BAY 1217389; Suppl. Table 1: Kinase selectivity profile of BAY 1161909; Suppl. Table 2: Kinase selectivity profile of BAY 1217389; Suppl. Table 3: Kinase sele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471af036b499cdbb44ed74a80af4d2c5
https://doi.org/10.1158/1535-7163.22508434.v1
https://doi.org/10.1158/1535-7163.22508434.v1
Autor:
Karl Ziegelbauer, Dominik Mumberg, Michael Brands, Franz von Nussbaum, Bertolt Kreft, Martin Michels, Oliver von Ahsen, Anna-Lena Frisk, Marian Raschke, Stefan Prechtl, Benjamin Bader, Philip Lienau, Roland Neuhaus, Detlef Stoeckigt, Ulrich Klar, Dirk Kosemund, Volker Schulze, Marcus Koppitz, Gerhard Siemeister, Antje M. Wengner
Effect of BAY 1161909 in monotherapy on the frequencies of peripheral blood reticulocytes and micronuclei-harboring reticulocytes in nude mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab6e5c8aa529b99980fb121751c20dc
https://doi.org/10.1158/1535-7163.22508443.v1
https://doi.org/10.1158/1535-7163.22508443.v1
Autor:
Thomas Steger-Hartmann, Marian Raschke
Publikováno v:
Current Opinion in Toxicology. :6-10
This review summarizes the recent advances in the field of investigative toxicology with a particular focus on the toxicological endpoint drug-induced liver injury. Despite the recent progress in the field of microphysiological systems with human cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e812dd9d8f8e0c4f81a05f13d3f4a83
https://doi.org/10.1016/j.cotox.2020.02.003
https://doi.org/10.1016/j.cotox.2020.02.003
Autor:
Gerhard Siemeister, Amaury Ernesto Fernandez-Montalvan, Volker K Schulze, Uwe Eberspaecher, Roland Neuhaus, Simon Holton, Stefan Prechtl, Michael Brands, Benjamin Bader, Marian Raschke, Duy Nguyen, Tobias Marquardt, Dirk Kosemund, Detlef Stöckigt, Ulf Bömer, Bertolt Kreft, Hartmut Schirok, Rolf Bohlmann, Antje Margret Wengner, Philip Lienau, Marcus Koppitz, Franz von Nussbaum, Rolf Jautelat, Michael Dr. Brüning, Hans Briem, Dominik Mumberg, Karl Ziegelbauer, Ulrich Klar, Olaf Döhr
Publikováno v:
Journal of Medicinal Chemistry. 63:8025-8042
Inhibition of monopolar spindle 1 (MPS1) kinase represents a novel approach to cancer treatment: instead of arresting the cell cycle in tumor cells, cells are driven into mitosis irrespective of DNA damage and unattached/misattached chromosomes, resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d455cb11862ac96ed455f56494ef1c0a
https://doi.org/10.1021/acs.jmedchem.9b02035
https://doi.org/10.1021/acs.jmedchem.9b02035
Autor:
Julia, Kühnlenz, Diana, Karwelat, Thomas, Steger-Hartmann, Marian, Raschke, Sophie, Bauer, Özlem, Vural, Uwe, Marx, Helen, Tinwell, Remi, Bars
Publikováno v:
ALTEX.
Thyroid hormones (THs) are crucial regulators of human metabolism and early development. During the safety assessment of plant protection products, the human relevance of chemically induced TH perturbations observed in test animals remains uncertain.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dfdf6f31758bed332e5edb1cbfd2eb8
https://doi.org/10.14573/altex.2108261
https://doi.org/10.14573/altex.2108261
Autor:
Diana, Karwelat, Julia, Kühnlenz, Thomas, Steger-Hartmann, Remi, Bars, Helen, Tinwell, Uwe, Marx, Sophie, Bauer, Oliver, Born, Marian, Raschke
Publikováno v:
ALTEX.
Endocrine disruption by environmental chemicals continues to be a concern for human safety. The rat, a widely used model organism in toxicology, is very sensitive to chemical-induced thyroid perturbation, e.g. histopathological alterations in thyroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c2688fa9f4b60c237d7b36e1e59cc08
https://doi.org/10.14573/altex.2108262
https://doi.org/10.14573/altex.2108262