Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Marian R. Fairgrieve"'
Autor:
Justin A. Roby, Katharina Esser-Nobis, Elyse C. Dewey-Verstelle, Marian R. Fairgrieve, Johannes Schwerk, Amy Y. Lu, Frank W. Soveg, Emily A. Hemann, Lauren D. Hatfield, Brian C. Keller, Alexander Shapiro, Adriana Forero, Jennifer E. Stencel-Baerenwald, Ram Savan, Michael Gale
Publikováno v:
Cells, Vol 9, Iss 4, p 899 (2020)
Pathogenic flaviviruses antagonize host cell Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling downstream of interferons α/β. Here, we show that flaviviruses inhibit JAK/STAT signaling induced by a wide range of cyt
Externí odkaz:
https://doaj.org/article/7543d266fff34f83bec7f5bdfb8814df
Autor:
Nir Yosef, Marian R Fairgrieve, Alyssa Kramer Morrow, Jonathan P Karr, Russell E. Vance, Moritz M. Gaidt
Publikováno v:
Nature, vol 600, iss 7887
Nature
Nature
Pathogens employ virulence factors to inhibit the immune system(1). The guard hypothesis(2,3) postulates that hosts monitor (or ‘guard’) critical innate immune pathways such that their disruption by virulence factors provokes a secondary immune r
Autor:
Susan L. Fink, Michael Gale, Olga Yakovenko, Michael Davis, Andreas B. den Hartigh, Christian Lood, Wendy E. Thomas, Marian R. Fairgrieve, Bhargavi Duvvuri
Publikováno v:
Proceedings of the National Academy of Sciences. 116:5061-5070
Pyroptosis is an inflammatory form of programmed cell death following cellular damage or infection. It is a lytic process driven by gasdermin D-mediated cellular permeabilization and presumed osmotic forces thought to induce swelling and rupture. We
Autor:
Elyse C. Dewey-Verstelle, Marian R. Fairgrieve, Frank Soveg, Emily A. Hemann, Jennifer E. Stencel-Baerenwald, Michael Gale, Ram Savan, Lauren D. Hatfield, Adriana Forero, Justin A Roby, Amy Y. Lu, Brian C. Keller, Alexander Shapiro, Katharina Esser-Nobis, Johannes Schwerk
Publikováno v:
Cells, Vol 9, Iss 899, p 899 (2020)
Cells
Volume 9
Issue 4
Cells
Volume 9
Issue 4
Pathogenic flaviviruses antagonize host cell Janus kinase/signal transducer and activator of transcription (JAK/STAT) signaling downstream of interferons &alpha
/&beta
Here, we show that flaviviruses inhibit JAK/STAT signaling induced by a
/&beta
Here, we show that flaviviruses inhibit JAK/STAT signaling induced by a
Autor:
Richard Green, Katharina Esser-Nobis, Justin A Roby, Marian R. Fairgrieve, Michael Gale, Lauren D Aarreberg
In recent years, Asian lineage Zika virus (ZIKV) strains emerged to cause pandemic outbreaks associated with a high rate of congenital ZIKV syndrome (CZVS). The reasons for the enhanced spread and severe disease caused by newly emerging strains are n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4c757a7d8ffff86093227620131b26
https://europepmc.org/articles/PMC6580957/
https://europepmc.org/articles/PMC6580957/
Autor:
Raj P. Kapur, William B. Dobyns, LaRene Kuller, Sean Merillat, Michelle Coleman, Branden R. Nelson, Audrey Baldessari, Kristina M. Adams Waldorf, Kara Jensen, Lakshmi Rajagopal, Kathryn A. Hanley, Jennifer E. Stencel-Baerenwald, Dennis W. W. Shaw, G. Michael Gough, Jeff Thiel, Joseph T. Medwid, Chris Gatenby, Ralph S. Baric, Justin A Roby, W. Mc Intyre Durning, Christie L. Walker, Elyse C. Dewey, Robert F. Hevner, Wonsok Lee, Erica Boldenow, Rebecca D. Hodge, Michael Gale, Jesica Swanstrom, Richard Grant, Michael Davis, Colin Studholme, Junwei Li, Manjiri Dighe, Jennifer Tisoncik-Go, Douglas G. Widman, Chris English, Jason Ogle, Jay Vornhagen, Verónica Santana-Ufret, Marian R. Fairgrieve, Xiaohu Gao, Blair Armistead
Publikováno v:
Nature medicine, vol 24, iss 3
Nature medicine
Nature medicine
Zika virus (ZIKV) is a flavivirus with teratogenic effects on fetal brain, but the spectrum of ZIKV-induced brain injury is unknown, particularly when ultrasound imaging is normal. In a pregnant pigtail macaque (Macaca nemestrina) model of ZIKV infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055e8421d048fa2a1dc009c0782d8469
https://escholarship.org/uc/item/27j088xp
https://escholarship.org/uc/item/27j088xp
Autor:
Chris English, Marian R. Fairgrieve, J. Christopher Gatenby, Gwenn A. Garden, Sean Merillat, Jeff Thiel, Robert F. Hevner, Jason Ogle, Wonsok Lee, Erica Boldenow, Colin Studholme, Lakshmi Rajagopal, Jay Vornhagen, Michael S. Diamond, Blair Armistead, Michael Gale, Dennis W. W. Shaw, Raj P. Kapur, Michael Davis, G. Michael Gough, William B. Dobyns, Todd L. Richards, Jennifer E. Stencel-Baerenwald, Audrey Baldessari, Kristina M. Adams Waldorf, La Rene Kuller, Richard Green, Sandra E. Juul, Richard Grant, Manjiri Dighe, Elyse C. Dewey, Jennifer Tisoncik-Go
Publikováno v:
Nature medicine. 22(11)
We describe the development of fetal brain lesions after Zika virus (ZIKV) inoculation in a pregnant pigtail macaque. Periventricular lesions developed within 10 d and evolved asymmetrically in the occipital-parietal lobes. Fetal autopsy revealed ZIK