Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marian N. Aziz"'
Publikováno v:
Molecules, Vol 28, Iss 2, p 618 (2023)
Spirooxindoles occupy an important place in heterocyclic chemistry. Many natural spirooxindole-containing compounds have been identified as bio-promising agents. Synthetic analogs have also been synthesized utilizing different pathways. The present a
Externí odkaz:
https://doaj.org/article/8312508bb06b41e7955045ee41806be2
Publikováno v:
Molecules, Vol 28, Iss 2, p 668 (2023)
Azomethine ylides are nitrogen-based three-atom components commonly used in [3+2]-cycloaddition reactions with various unsaturated 2π-electron components. These reactions are highly regio- and stereoselective and have attracted the attention of orga
Externí odkaz:
https://doaj.org/article/8cff564e555b4c5cac017f834abbeb49
Autor:
Marian N. Aziz, Arzoo Patel, Amany Iskander, Avisankar Chini, Delphine Gout, Subhrangsu S. Mandal, Carl J. Lovely
Publikováno v:
Molecules, Vol 27, Iss 3, p 841 (2022)
An efficient surface-mediated synthetic method to facilitate access to a novel class of thiazolidines is described. The rationale behind the design of the targeted thiazolidines was to prepare stable thiazolidine analogues and evaluate their anti-pro
Externí odkaz:
https://doaj.org/article/440c6b3ad2294e498bd302b92c760d89
Publikováno v:
European journal of medicinal chemistry. 246
The discovery of a new class of extracellular-signal-regulated kinase (ERK) inhibitors has been achieved via developing novel 2-imino-5-arylidene-thiazolidine analogues. A novel synthetic method employing a solid support-mediated reaction was used to
Publikováno v:
Journal of Chemical Research. 42:90-95
Two azaphenanthrenes were synthesised by a facile synthetic pathway and characterised by X-ray crystallography. Molecular packing of 4-(2,4-dichlorophenyl)-2-methoxy-5,6-dihydrobenzo[ h]quinoline-3-carbonitrile exhibits C–H…N and C–H…Cl hydro
Publikováno v:
Tetrahedron Letters. 72:153054
An investigation of the dearomatization reactions of benzylic thioureas, ureas and guanidines using hypervalent iodine reagents is described. Initial attempts to perform this reaction with methyl aryl ethers was compromised by electrophilic addition
Autor:
Adel S. Girgis, ElSayed M. Shalaby, Siva S. Panda, N. Mishriky, F. M. Asaad, Marian N. Aziz, E. A. Soliman
Publikováno v:
European Journal of Medicinal Chemistry. 138:920-931
Facile synthetic pathway for nicotinonitriles 5a‒o, 7a‒i was demonstrated through reaction of ketones 4a‒k, 6a‒f with ylidenemalononitrile 3 in the presence of sodium alkoxide. Meanwhile, nucleophilic attack of amines on 2-bromonicotinonitril
Publikováno v:
RSC advances. 9(49)
A Facile synthetic approach is reported towards 4-hydroxyquinazoline-4-carboxamides 13a–i through ring expansion of 2,3-dioxoindoline-1-carboxamides 10a–c during secondary amine 11a–d nucleophilic reaction. Single crystal X-ray studies of 10c a
Autor:
ElSayed M. Shalaby, Dalia O. Saleh, Adel S. Girgis, I. S. Ahmed Farag, Marian N. Aziz, Wafaa I. El-Eraky, F. M. Asaad
Publikováno v:
Journal of Chemical Crystallography. 46:280-289
Benzocycloheptapyridines 6a and 6b were characterized by single crystal X-ray diffraction. Molecular packing exhibits that, molecules of compound 6a are linked in chains by one hydrogen bond of C–H···N type and set of H–π, and Cl–π interac
Autor:
Adel S. Girgis, N. Mishriky, I. S. Ahmed Farag, ElSayed M. Shalaby, Dalia O. Saleh, Wafaa I. El-Eraky, Marian N. Aziz
Publikováno v:
Zeitschrift für Kristallographie - Crystalline Materials. 231:179-187
Two 5H-indeno[1,2-b]pyridines, 7a and 7b, were synthesized and characterized by X-ray crystallography. In the molecular packing, molecules of 7a are linked into chains by C–H···N hydrogen bond which, in turn, are connected by H···π, N···