Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Marian L. Lewis"'
Autor:
Luis Cubano, Marian L. Lewis
Publikováno v:
Journal of Leukocyte Biology. 69:755-761
Heat shock protein levels are increased in cells as a result of exposure to stress. To determine whether heat shock protein regulation could be used to evaluate stress in cells during spaceflight, the response of Jurkat cells to spaceflight and simul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab32c217adc76ddd78463cfc1458cab3
https://doi.org/10.1189/jlb.69.5.755
https://doi.org/10.1189/jlb.69.5.755
Autor:
Marian L. Lewis, Luis A Cubano
Publikováno v:
Experimental Gerontology. 35:389-400
Human lymphocytes flown on the Space Shuttle respond poorly to mitogen stimulation and populations of the lymphoblastoid T cell line, Jurkat, manifest growth arrest, increase in apoptosis and time- and microgravity-dependent increases in the soluble
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b55afa88df38c1456e8aaa3aecf3403f
https://doi.org/10.1016/s0531-5565(00)00090-5
https://doi.org/10.1016/s0531-5565(00)00090-5
Autor:
Marian L. Lewis, Millie Hughes-Fulford
Publikováno v:
Journal of Cellular Biochemistry. 77:127-134
Although our understanding of effects of space flight on human physiology has advanced significantly over the past four decades, the potential contribution of stress at the cellular and gene regulation level is not characterized. The objective of thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16592d02a5605e521248fa18b8aaed4a
https://doi.org/10.1002/(sici)1097-4644(20000401)77:1<127::aid-jcb13>3.0.co
https://doi.org/10.1002/(sici)1097-4644(20000401)77:1<127::aid-jcb13>3.0.co
Autor:
Sylvie B. Roquefeuil, Marian L. Lewis, Jason P. Hatton, Didier A. Schmitt, Didier Chaput, Jean-Pierre Cazenave
Publikováno v:
Journal of Cellular Biochemistry. 70:252-267
The results of experiments performed in recent years on board facilities such as the Space Shuttle/Spacelab have demonstrated that many cell systems, ranging from simple bacteria to mammalian cells, are sensitive to the microgravity environment, sugg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df18c68dbe698861d826b98cc08de882
https://doi.org/10.1002/(sici)1097-4644(19980801)70:2<252::aid-jcb11>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19980801)70:2<252::aid-jcb11>3.0.co
Publikováno v:
Experimental Cell Research. 237:410-418
An immortalized promyelocytic cell line was studied to detect how doxorubicin uptake is affected by microgravity. The purpose of this experiment was to identify the effect that microgravity may have on multidrug resistance in leukocytes. HL60 cells a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44daee3565b807118133673ae79b0309
https://doi.org/10.1006/excr.1997.3813
https://doi.org/10.1006/excr.1997.3813
Use of microgravity bioreactors for development of an in vitro rat salivary gland cell culture model
Publikováno v:
Journal of Cellular Biochemistry. 51:265-273
During development, salivary gland (SG) cells both secrete factors which modulate cellular behavior and express specific hormone receptors. Whether SG cell growth is modulated by an autocrine epidermal growth factor (EGF) receptor-mediated signal tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40eb5b24f5e6db07d1ab00146b4e4eb1
https://doi.org/10.1002/jcb.240510305
https://doi.org/10.1002/jcb.240510305
Autor:
Marian L. Lewis
Publisher Summary Lymphocytes exposed to spaceflight or altered gravity exhibit significant growth attenuation and changes in metabolism, cytoskeletal structure, and gene expression. A significant body of evidence is accumulating to implicate the cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f8b10b90e1d7d08cbf5789b7328e9796
https://doi.org/10.1016/s1569-2574(02)08016-4
https://doi.org/10.1016/s1569-2574(02)08016-4
Publikováno v:
Acta astronautica. 49(3-10)
The cytoskeleton is a complex network of fibers that is sensitive to environmental factors including microgravity and altered gravitational forces. Cellular functions such as transport of cell organelles depend on cytoskeletal integrity; regulation o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac21646c5142de77e4d9d1fe63bf92e2
https://pubmed.ncbi.nlm.nih.gov/11669127
https://pubmed.ncbi.nlm.nih.gov/11669127
Autor:
Jonathan G. Pabalan, Luis Cubano, Marian L. Lewis, Baiteng Zhao, Hong-Khanh B. Dinh, Edward H. Piepmeier, Phillip D. Bowman
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 15(10)
SPECIFIC AIMSThis study addresses the hypothesis that in addition to previously reported microtubule disruption and growth arrest, spaceflight may alter expression of genes to fundamentally affect cytoskeletal and cellular function. The effect of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb4dfe8b2ba7cf2139b2637ad2e18e86
https://pubmed.ncbi.nlm.nih.gov/11481229
https://pubmed.ncbi.nlm.nih.gov/11481229
Autor:
Marian L. Lewis, Yann Darsel, Philippe Ohlmann, Jean-Pierre Cazenave, Jason P. Hatton, François Gaubert, Didier A. Schmitt
Publikováno v:
The FASEB Journal. 13
Protein kinase C (PKC) is a family of serine/threonine kinases that play an important role in mediating intracellular signal transduction in eukaryotes. U937 cells were exposed to microgravity during a space shuttle flight and stimulated with a radio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7e7703e027b3080c1fb2364607676f
https://doi.org/10.1096/fasebj.13.9001.s23
https://doi.org/10.1096/fasebj.13.9001.s23