Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Marian L, Kruzel"'
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2429 (2022)
Lung cancer continues to be the deadliest cancer worldwide. A new strategy of combining chemotherapeutics with naturally occurring anticancer compounds, such as lactoferrin, might improve the efficacy and toxicity of current chemotherapy. The aim of
Externí odkaz:
https://doaj.org/article/2cdd9780465d4bcaa0a7c338ba10c1ce
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 898 (2021)
Pregnancy is a physiological state that demands higher level of nutrients, including vitamins and minerals, for the growth and maintenance of the fetus. Iron deficiency is a part of most common diet deficiencies in pregnancy and has high clinical sig
Externí odkaz:
https://doaj.org/article/56e0aa97a40c4e179567df850f04660f
Publikováno v:
BioMetals. 36:603-615
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Much progress has been achieved to elucidate the function of lactoferrin (LTF), an iron-binding glycoprotein, in the milieu of immune functionality. This review represents a unique examination of LTF toward its importance in physiologic homeostasis a
Externí odkaz:
https://doaj.org/article/4c1c3311e7a14d7fabb104b897c2aeb9
Publikováno v:
Biochemistry and Cell Biology. 99:47-53
The immunomodulatory nature of lactoferrin (LF) derives from its ability to bridge innate and adaptive immunity in obtaining physiological equilibrium. LF is an attractive molecule for treatment of diseases that compromise immune homeostasis. Oral de
Autor:
John d'Aigle, Marian L. Kruzel, Zainab Niaz, Shen-An Hwang, Thao K.T. Nguyen, Jeffrey K. Actor
Publikováno v:
Biochemistry and Cell Biology. 99:73-80
Primary infection with Mycobacterium tuberculosis (Mtb) results in the formation of a densely packed granulomatous response that essentially limits the entry and efficacy of immune effector cells. Furthermore, the physical nature of the granuloma doe
Publikováno v:
Biochemistry and Cell Biology. 99:97-101
In this minireview we discuss the role of lactoferrin (LTF) in detoxifying hematoma after intracerebral hemorrhage (ICH). Subsequent to ICH, neutrophils enter the ICH-affected brain, where they release various granule contents, including LTF. LTF is
Autor:
Ewa Zaczyńska, Maja Kocięba, Jolanta Artym, Iwona Kochanowska, Marian L. Kruzel, Michał Zimecki
Publikováno v:
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine.
Lactoferrin (LTF) is a natural iron-binding protein with a potential for clinical utility in many human immune disorders, including cancer. A fusion of LTF with the Fc domain of IgG2 (FcLTF) was designed with inherent properties of an extended the ha
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis. 70
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis
Lung cancer remains the leading cause of cancer death worldwide. Despite the recent advances in cancer treatment, only a subset of patients responds to targeted and immune therapies, and many patients developing resistance after an initial response.