Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Marian J. Evinger"'
Publikováno v:
Neuroscience. 147:928-937
Pheochromocytomas are adrenal medullary tumors that typically occur in adult patients, with increased frequency in multiple endocrine neoplasia type 2, von Hippel-Lindau disease, familial paraganglioma syndromes and neurofibromatosis type 1 (NF1). Ph
Publikováno v:
Experimental Cell Research. 313:772-781
Specific arrays and timing of environmental cues including glucocorticoids, neurotrophic factors and intracellular messengers influence phenotype expression in developing chromaffin cells or sympathetic neurons. Although the two lineages are closely
Publikováno v:
Journal of Molecular Neuroscience. 12:53-68
Expression of the gene encoding the epinephrine-synthesizing enzyme phenylethanolamine N-methyltransferase (PNMT) is regulated by hormonal and neural stimuli. Because the 5'-upstream regions of the PNMT do not contain sequences analogous to those dem
Publikováno v:
Neuroscience Letters. 201:77-80
The human medulloblastoma TE 671 cell line has been evaluated as a model for studying expression of transiently transfected phenylethanolamine N-methyltransferase (PNMT) promoter-fusion gene constructs. Because TE 671 cells are one of few continuous
Publikováno v:
Molecular Brain Research. 16:215-222
Our earlier work demonstrated that certain populations of brain neurons which do not synthesize catecholamine (CA) neurotransmitters in vivo, will, when grown in culture with muscle-derived differentiation factor (MDF), unexpectedly express the gene
Publikováno v:
Neuroscience Letters. 141:208-212
The effects of unilateral mechanical transection of the nigrostriatal bundle of rat brain on the level of tyrosine hydroxylase (TH) mRNA and on the activity of TH enzyme in the substantia nigra (SN) were examined. Lesions resulted, by 14 days, in red
Autor:
Esam E. El-Fakahany, John C.R. Fernando, Marian J. Evinger, Elsayed A. M. Abdallah, Carlos Forray
Publikováno v:
European Journal of Pharmacology: Molecular Pharmacology. 207:297-303
The muscarinic receptor subtype present in the bovine adrenal medulla was characterized. Hybridization of RNA to highly specific m 1 –m 5 muscarinic receptor cDNA probes detected the presence of only m 4 subtype mRNA in this tissue. Muscarinic rece
Autor:
Stefan Cikos, Arthur S. Tischler, Victoria N Nwafor-Anene, Marian J. Evinger, James F. Powers
Publikováno v:
Annals of the New York Academy of Sciences. 971
Mouse pheochromocytoma cells (MPCs) provide an excellent model system for investigating the effects of hypoxia on catecholamine enzyme genes and on transcription factors mediating stress responses. RT-PCR detects rapid, transient increases in PNMT mR
Autor:
James F. Powers, Mohsen Shahsavari, Marian J. Evinger, Shahinaz Bedri, Joseph Alroy, Arthur S. Tischler, Panayiotis Tsokas
Publikováno v:
Cell and tissue research. 302(3)
Transplantable tumors and cell lines have been developed from pheochromocytomas arising in mice with a heterozygous knockout mutation of the neurofibromatosis gene, Nf1. Nf1 encodes a ras-GTPase-activating protein, neurofibromin, and mouse pheochromo
Publikováno v:
Journal of molecular neuroscience : MN. 9(2)
Pituitary adenylate cyclase activating polypeptide (PACAP) elevates levels of the mRNAs encoding the catecholamine synthesizing enzymes tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DBH), and phenylethanolamine N-methyltransferase (PNMT) in p