Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Marian E Major"'
Autor:
Eric Tatara, Alexander Gutfraind, Nicholson T Collier, Desarae Echevarria, Scott J Cotler, Marian E Major, Jonathan Ozik, Harel Dahari, Basmattee Boodram
Publikováno v:
PLoS ONE, Vol 17, Iss 3, p e0264983 (2022)
Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease and mortality worldwide. Direct-acting antiviral (DAA) therapy leads to high cure rates. However, persons who inject drugs (PWID) are at risk for reinfection after cure and
Externí odkaz:
https://doaj.org/article/e0ee7e76f0c34240857dcab816fe6a41
Autor:
Wendy G Tan, Iryna Zubkova, Alla Kachko, Frances Wells, Heiko Adler, Gerd Sutter, Marian E Major
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181578 (2017)
T-cell based vaccines have been considered as attractive candidates for prevention of hepatitis C virus (HCV) infections. In this study we compared the magnitude and phenotypic characteristics of CD8+ T-cells induced by three commonly used viral vect
Externí odkaz:
https://doaj.org/article/2229ae1085654a6284af5f2bf284757e
Autor:
Alexander Gutfraind, Basmattee Boodram, Nikhil Prachand, Atesmachew Hailegiorgis, Harel Dahari, Marian E Major
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137993 (2015)
People who inject drugs (PWID) are at high risk for blood-borne pathogens transmitted during the sharing of contaminated injection equipment, particularly hepatitis C virus (HCV). HCV prevalence is influenced by a complex interplay of drug-use behavi
Externí odkaz:
https://doaj.org/article/7c26e74e5ed545f38f6101233581b5f5
Autor:
Marian E. Major, Nicole Frumento, Alexander W. Tarr, Johnathan D. Guest, Steven K. H. Foung, Arvind H. Patel, Alexis Figueroa, Jordan Salas, Jonathan K. Ball, Vanessa M. Cowton, Kaitlyn E. Clark, Heidi E. Drummer, Thomas R. Fuerst, Richard A. Urbanowicz, Sarah Cole, Brian G. Pierce, Zhen-Yong Keck, Mansun Law, Justin R. Bailey
Publikováno v:
Gastroenterology. 162:562-574
Background and Aims Development of a prophylactic hepatitis C virus (HCV) vaccine will require accurate and reproducible measurement of neutralizing breadth of vaccine-induced antibodies. Currently available HCV panels may not adequately represent th
Autor:
Sylvie Chabot, Yusra Gimie, Karam Obeid, Jaekwan Kim, Clement A. Meseda, Krishnamurthy Konduru, Gerardo Kaplan, Li Sheng Fowler, Jerry P. Weir, Keith Peden, Marian E. Major
Publikováno v:
J Virol
Studies on Ebola virus disease (EVD) survivors and clinical studies on Ebola virus (EBOV) vaccine candidates have pinpointed the importance of a strong antibody response in protection and survival from EBOV infection. However, little is known about t
Autor:
Marian E. Major
Publikováno v:
Viruses, Vol 1, Iss 2, Pp 144-165 (2009)
Studies in patients and chimpanzees that spontaneously clear Hepatitis C Virus (HCV) have demonstrated that natural immunity to the virus is induced during primary infections and that this immunity can be cross protective. These discoveries led to op
Externí odkaz:
https://doaj.org/article/1b4cfafba169466eba79000cc2c776b1
Autor:
Basmattee Boodram, Harel Dahari, Marian E. Major, Alexander Gutfraind, Jonathan Ozik, Eric Tatara, Scott J. Cotler, Nicholson Collier
Publikováno v:
Proc Winter Simul Conf
WSC
WSC
Hepatitis C (HCV) is a leading cause of chronic liver disease and mortality worldwide and persons who inject drugs (PWID) are at the highest risk for acquiring and transmitting HCV infection. We developed an agent-based model (ABM) to identify and op
Autor:
Harel Dahari, Basmattee Boodram, Marian E. Major, Alexander Gutfraind, Eric Tatara, Scott J. Cotler, Jonathan Ozik, Nicholson Collier, Desarae Echevarria
Hepatitis C virus (HCV) infection is a leading cause of chronic liver disease and mortality worldwide. Direct-acting antiviral (DAA) therapy leads to high cure rates. However, persons who inject drugs (PWID) are at risk for reinfection after cure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3546366f01ee836f55b381cbe3441b9b
https://doi.org/10.1101/653196
https://doi.org/10.1101/653196
Autor:
Mansun Law, Marian E. Major
Publikováno v:
Methods in Molecular Biology ISBN: 9781493989751
Enzyme-linked immunosorbent assays (ELISAs) enable rapid detection and quantitation of antibodies in samples. Such assays can be highly sensitive and can be performed in most laboratories with basic equipment. Although detecting binding antibodies to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c8fd707af296c01a83e933b621f360b
https://doi.org/10.1007/978-1-4939-8976-8_28
https://doi.org/10.1007/978-1-4939-8976-8_28
Autor:
Alexander Gutfraind, Basmattee Boodram, Kimberly Page, Qingwen Cui, Behzad Hajarizadeh, Rachel Sacks-Davis, Harel Dahari, Alla Kachko, Louis M. Shekhtman, Scott J. Cotler, Marian E. Major
Publikováno v:
Science Translational Medicine. 10
The major route of hepatitis C virus (HCV) transmission in the United States is injection drug use. We hypothesized that if a HCV vaccine was available, vaccination could impact HCV transmission among people who inject drugs by reducing HCV titers af