Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Marian C. Bryan"'
Autor:
Marian C. Bryan, Charlotte Dalton, Alba Díaz-Rodríguez, Jaika Doerfler, Oliver D. Engl, Alejandro Gimenez Molina, Vanessa Harawa, Christopher B. Kelly, Wei Li, Rachel H. Munday, Jan Pawlas, Paul F. Richardson, William J. Smith, Alan Steven, Balaram S. Takale, Jack A. Terrett, Daniel S. Treitler, Mingshuo Zeng
Publikováno v:
Organic Process Research & Development. 27:563-570
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75cfa86fb3968343526278f23eeebbad
https://doi.org/10.1021/acs.oprd.3c00065
https://doi.org/10.1021/acs.oprd.3c00065
Autor:
Marian C. Bryan, David Wernick, Christopher D. Hein, James V. Petersen, John W. Eschelbach, Elizabeth M. Doherty
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 7, Iss 1, Pp 1141-1149 (2011)
The performance of the ThalesNano H-Cube®, a commercial packed bed flow hydrogenator, was evaluated in the context of small scale reaction screening and optimization. A model reaction, the reduction of styrene to ethylbenzene through a 10% Pd/C cata
Externí odkaz:
https://doaj.org/article/09c0d6d4330a444483bf352447f1b7db
Autor:
Lucinda Tam, Annemarie Lekkerkerker, Jeffrey Eastham-Anderson, Melanie Domeyer, Brent S. McKenzie, Azadeh Hadadianpour, Eugene Varfolomeev, Arna Katewa, Steven Do, A. Francesca Setiadi, Wyne P. Lee, Joy Drobnick, Andres Paler-Martinez, Rajita Pappu, Katherine Bao, Marian C. Bryan, Alfred Wong, James J. Crawford, Cesar A. Corzo, Vida Asghari, Sha Klabunde, Vladimir Ramirez-Carrozi, Jodie Pang, Jason A. Hackney, Hans Brightbill, Christopher Dela Cruz, Ross Francis, Yonglian Sun, Merone Roose-Girma, Claire Emson, Wendy B. Young, Michael J. Townsend, James R. Kiefer, Cary D. Austin, Swathi Sujatha-Bhaskar, Emily Hunley, Nico Ghilardi, Daqi Xu, Søren Warming, Kate Senger, Zhiyu Huang, Vivian W. C. Lau, Domagoj Vucic, Ali A. Zarrin, Eric Suto
Publikováno v:
Science signaling. 13(634)
The dysregulation of multiple signaling pathways, including those through endosomal Toll-like receptors (TLRs), Fc gamma receptors (FcγR), and antigen receptors in B cells (BCR), promote an autoinflammatory loop in systemic lupus erythematosus (SLE)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df56c99041e31c3d42be9d115b0561d
https://pubmed.ncbi.nlm.nih.gov/32487715
https://pubmed.ncbi.nlm.nih.gov/32487715
Autor:
David Entwistle, Michael E. Kopach, Matthew R. Hickey, John D. Hayler, Frank Roschangar, Peter J. Dunn, Fabrice Gallou, Shaun Hughes, Franz J. Weiberth, Stefan G. Koenig, Alan Steven, Gerard Moine, Marian C. Bryan, Paul G. Richardson
Publikováno v:
Green Chemistry. 20:5082-5103
In 2007 the members of the ACS Green Chemistry Institute® Pharmaceutical Roundtable assembled a list of key green chemistry research areas to both identify transformations that would benefit from improvements in process greenness and to encourage ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c96b8a6cbe2927cd57622eff9cadbb2
https://doi.org/10.1039/c8gc01276h
https://doi.org/10.1039/c8gc01276h
Autor:
Mark D. McLaws, Zhongbo Fei, Andrew Cosbie, Louis J. Diorazio, Paul G. Richardson, Marian C. Bryan, Timothy D. White, Jingjun Yin, Kenneth J. Fraunhoffer, Matthew R. Hickey, Alan Steven, Shaun Hughes, Gheorghe-Doru Roiban, Markus Schober, John D. Hayler
Publikováno v:
Organic Process Research & Development. 21:1464-1477
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55945dd935d2abd4d6f5e0132f99c156
https://doi.org/10.1021/acs.oprd.7b00292
https://doi.org/10.1021/acs.oprd.7b00292
Autor:
Marian C. Bryan, Louis Diorazio, Zhongbo Fei, Kenneth Fraunhoffer, John Hayler, Matthew Hickey, Shaun Hughes, Luke Humphreys, Paul Richardson, Markus Schober, Alan Steven, Timothy White, Stijn Wuyts, Jingjun Yin
Publikováno v:
Organic Process Research & Development. 21:153-164
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85db5a2a33f8dd03eb70b0ed58a0d57c
https://doi.org/10.1021/acs.oprd.7b00014
https://doi.org/10.1021/acs.oprd.7b00014
Autor:
Zhiyu Huang, Yingqing Ran, Le An, Alberto Gobbi, Jonathan Maher, Claire Emson, Naomi S. Rajapaksa, Edna F. Choo, Yongsheng Chen, Steven Do, Aleksandr Kolesnikov, Ali A. Zarrin, Christine Yu, Marian C. Bryan, Joy Drobnick, Swathi Sujatha-Bhaskar, Hans Brightbill, James R. Kiefer, Jun Liang, Brent S. McKenzie, Ross Francis, John S. Wai, Patrick J. Lupardus, Kevin DeMent
Publikováno v:
ACS Med Chem Lett
[Image: see text] IRAK4 kinase activity transduces signaling from multiple IL-1Rs and TLRs to regulate cytokines and chemokines implicated in inflammatory diseases. As such, there is high interest in identifying selective IRAK4 inhibitors for the tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c741d6c5a8d5445e4411ce0bee8e8c5
https://europepmc.org/articles/PMC7073891/
https://europepmc.org/articles/PMC7073891/
Autor:
Patrick J. Lupardus, Yongsheng Chen, Naomi S. Rajapaksa, John S. Wai, Kevin DeMent, Edna F. Choo, Brent S. McKenzie, Ross Francis, Joy Drobnick, Hans Brightbill, James R. Kiefer, Willy M. Chang, Chudi Ndubaku, Alberto Gobbi, Antonio G. DiPasquale, Aleksandr Kolesnikov, Jonathan Maher, Jianwen Feng, Claire Emson, Le An, Ali A. Zarrin, Zhiyu Huang, Christine Yu, Yingqing Ran, Marian C. Bryan, Swathi Sujatha-Bhaskar
Publikováno v:
Journal of medicinal chemistry. 62(13)
A series of pyrazolopyrimidine inhibitors of IRAK4 were developed from a high-throughput screen (HTS). Modification of an HTS hit led to a series of bicyclic heterocycles with improved potency and kinase selectivity but lacking sufficient solubility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0004b792a5f5c3e407829d184818a26
https://pubmed.ncbi.nlm.nih.gov/31082230
https://pubmed.ncbi.nlm.nih.gov/31082230
Autor:
Rakeshwar Bandichhor, Apurba Bhattacharya, Marian C. Bryan, Louis Diorazio, Peter Dunn, Kenneth Fraunhoffer, Fabrice Gallou, John Hayler, Matthew Hickey, Luke Humphreys, Paul Richardson, Gheorghe-Doru Roiban, Timothy White, Stijn Wuyts, Jingjun Yin
Publikováno v:
Organic Process Research & Development. 20:707-717
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa7f145bef980dcec582f3ad15610a7f
https://doi.org/10.1021/acs.oprd.6b00042
https://doi.org/10.1021/acs.oprd.6b00042