Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mariama C. Maiga"'
Autor:
Mamoudou Maiga, Bintou Ahmadou Ahidjo, Mariama C. Maiga, Laurene Cheung, Shaaretha Pelly, Shichun Lun, Flabou Bougoudogo, William R. Bishai
Publikováno v:
EBioMedicine, Vol 2, Iss 8, Pp 868-873 (2015)
The global tuberculosis (TB) epidemic and the spread of multi- and extensively-drug resistant strains of Mycobacterium tuberculosis (M.tb) have been fueled by low adherence to following lengthy treatment protocols, and the rapid spread of HIV (Human
Externí odkaz:
https://doaj.org/article/ce287b592ab84b79a5a7c78095b20ade
Autor:
Shichun Lun, David Miranda, Andre Kubler, Haidan Guo, Mariama C. Maiga, Kathryn Winglee, Shaaretha Pelly, William R. Bishai
Publikováno v:
mBio, Vol 5, Iss 5 (2014)
ABSTRACT Most β-lactam antibiotics are ineffective against Mycobacterium tuberculosis due to the microbe’s innate resistance. The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has prompted interest to repurpos
Externí odkaz:
https://doaj.org/article/e2d9cd97723049a59e324f884a5cd039
Autor:
Mamoudou Maiga, Seong Won Choi, Viorel Atudorei, Mariama C. Maiga, Zachary D. Sharp, William R. Bishai, Graham S. Timmins
Publikováno v:
mBio, Vol 5, Iss 2 (2014)
ABSTRACT One of the major hurdles in treating tuberculosis (TB) is the time-consuming and difficult methodology for diagnosis. Stable-isotope breath tests hold great potential for rapidly diagnosing an infectious disease, monitoring therapy, and dete
Externí odkaz:
https://doaj.org/article/851a2229eb62494c94bb4c36f2be6d40
Autor:
Mamoudou Maiga, Bintou Ahmadou Ahidjo, Mariama C. Maiga, Laurene Cheung, Shaaretha Pelly, Shichun Lun, Flabou Bougoudogo, William R. Bishai
Publikováno v:
EBioMedicine, Vol 2, Iss 11, p 1834 (2015)
Externí odkaz:
https://doaj.org/article/f0477d354a5241ecb4dd3d28f9cbfcbc
Autor:
Mamoudou Maiga, William R. Bishai, Gobardhan Das, Mariama C. Maiga, Ved Prakash Dwivedi, Debapriya Bhattacharya, Luc Van Kaer
Publikováno v:
The Journal of Biological Chemistry
Background: M. tuberculosis evades host-immune-responses by polarizing T helper (Th)2 and regulatory T cell (Treg) responses, which diminish protective Th1 responses. Results: Mice that are unable to generate Th2 cells and Tregs are resistant to M. t
Autor:
Shashank Gupta, William R. Bishai, Mariama C. Maiga, Sandeep Tyagi, Nicole C. Ammerman, Deepak V. Almeida
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 188:600-607
Rationale: A major priority in tuberculosis (TB) is to reduce effective treatment times and emergence of resistance. Recent studies in macrophages and zebrafish show that inhibition of mycobacterial efflux pumps with verapamil reduces the bacterial d
Autor:
Anatole Tounkara, Mariama C. Maiga, William R. Bishai, Nicole C. Ammerman, Robert L. Murphy, Sophia Siddiqui, Michael A. Polis, Mamoudou Maiga
Publikováno v:
The Journal of Infectious Diseases. 208:512-519
Background. Shortening tuberculosis treatment could significantly improve patient adherence and decrease the development of drug resistance. Phosphodiesterase inhibitors (PDE-Is) have been shown to be beneficial in animal models of tuberculosis. We a
Autor:
Alvaro A. Ordonez, Elizabeth A. Ihms, William R. Bishai, Sanjay K. Jain, Laurene S. Cheung, Bruno B. Andrade, Sarah E. Beck, Mariama C. Maiga, Mamoudou Maiga, Bintou Ahmadou Ahidjo
Publikováno v:
JCI Insight. 1
Pirfenidone is a recently approved antifibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). Because tuberculosis (TB) is characterized by granulomatous inflammation in conjunction with parenchymal destruction and replacement fibros
Autor:
Mariama C. Maiga, David Miranda, Andre Kubler, Kathryn Winglee, Shichun Lun, Haidan Guo, William R. Bishai, Shaaretha Pelly
Publikováno v:
mBio, Vol 5, Iss 5 (2014)
mBio
mBio
Most β-lactam antibiotics are ineffective against Mycobacterium tuberculosis due to the microbe’s innate resistance. The emergence of multidrug-resistant (MDR) and extensively drug-resistant (XDR) strains has prompted interest to repurpose this cl
Autor:
Mariama C. Maiga, Graham S. Timmins, Mamoudou Maiga, Seong Won Choi, William R. Bishai, Viorel Atudorei, Zachary D. Sharp
Publikováno v:
Nature communications
There is urgent need for rapid, point-of-care diagnostic tools for tuberculosis (TB) and drug sensitivity. Current methods based on in vitro growth take weeks, while DNA amplification can neither differentiate live from dead organisms nor determine p