Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic young adults.

Autor: Narcisse Patrice Komas, Sumantra Ghosh, Mariama Abdou-Chekaraou, Pierre Pradat, Nasser Al Hawajri, Alexandre Manirakiza, Gina Laure Laghoe, Claudine Bekondi, Ségolène Brichler, Jean-Omer Ouavéné, Abdoulaye Sépou, Brice Martial Yambiyo, Jean Chrysostome Gody, Valentin Fikouma, Athénais Gerber, Natali Abeywickrama Samarakoon, Dulce Alfaiate, Caroline Scholtès, Nora Martel, Frédéric Le Gal, Hugo Lo Pinto, Ikram Amri, Olivier Hantz, David Durantel, Jean-Louis Lesbordes, Emmanuel Gordien, Philippe Merle, Tudor Drugan, Christian Trépo, Fabien Zoulim, Jean-Claude Cortay, Alan Campbell Kay, Paul Dény

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006377 (2018)

Hepatitis delta virus (HDV) increases morbidity in Hepatitis B virus (HBV)-infected patients. In the mid-eighties, an outbreak of HDV fulminant hepatitis (FH) in the Central African Republic (CAR) killed 88% of patients hospitalized in Bangui. We eva

Externí odkaz: https://doaj.org/article/0abca25d0aea44c08a946e3258bb48aa

Higher Mortality Despite Early Antiretroviral Therapy in Human Immunodeficiency Virus and Hepatitis B Virus (HBV)–Coinfected Patients With High HBV Replication

Autor: Anani Badje, Anders Boyd, Jean-Baptiste Ntakpe, Delphine Gabillard, Fabien Zoulim, Christine Danel, Eric Ouattara, Xavier Anglaret, Serge-Paul Eholié, Arlette Emieme, Raoul Moh, Mariama Abdou Chekaraou, Sarah Maylin, Gérard-Menan Kouamé, Anrs VarBVA Study Groups, Karine Lacombe

Publikováno v: Clinical Infectious Diseases. 66:112-120

Background In human immunodeficiency virus (HIV)-infected patients, hepatitis B virus (HBV) coinfection increases the risk of disease progression. Tenofovir plus emtricitabine/lamivudine (TDF/XTC)-based antiretroviral therapy (ART), which suppresses

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9729523bac02ce93c84c3e3350c77d34
https://doi.org/10.1093/cid/cix747

Hepatitis B and hepatitis D virus infections in the Central African Republic, twenty-five years after a fulminant hepatitis outbreak, indicate continuing spread in asymptomatic young adults

Autor: Frédéric Le Gal, Jean-Louis Lesbordes, Valentin Fikouma, Ségolène Brichler, Paul Dény, Fabien Zoulim, Hugo Lo Pinto, Philippe Merle, Mariama Abdou-Chekaraou, Nasser Al Hawajri, Natali Abeywickrama Samarakoon, Narcisse P Komas, Jean Chrysostome Gody, Jean-Claude Cortay, Emmanuel Gordien, Christian Trepo, Alexandre Manirakiza, Pierre Pradat, Ikram Amri, Claudine Bekondi, Abdoulaye Sépou, Nora Martel, Athenaïs Gerber, Alan Kay, Caroline Scholtes, Brice Martial Yambiyo, Jean-Omer Ouavéné, Sumantra Ghosh, Gina Laure Laghoe, Tudor Drugan, David Durantel, Olivier Hantz, Dulce Alfaiate

Publikováno v: PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006377 (2018)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Public Library of Science, 2018, 12 (4), pp.e0006377. ⟨10.1371/journal.pntd.0006377⟩

Hepatitis delta virus (HDV) increases morbidity in Hepatitis B virus (HBV)-infected patients. In the mid-eighties, an outbreak of HDV fulminant hepatitis (FH) in the Central African Republic (CAR) killed 88% of patients hospitalized in Bangui. We eva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8821fcbdc9f4bd0c1680edb29898ee5f
http://europepmc.org/articles/PMC5940242?pdf=render

Effect of hepatitis B virus (HBV) surface-gene variability on markers of replication during treated human immunodeficiency virus-HBV infection in Western Africa

Autor: Nadia Mahjoub, Anrs VarBVA study, Anders Boyd, Xavier Anglaret, Sarah Maylin, Christine Danel, Fabien Zoulim, Raoul Moh, Karine Lacombe, Delphine Gabillard, Serge Eholié, Constance Delaugerre, Mariama Abdou Chekaraou

Publikováno v: Liver international : official journal of the International Association for the Study of the Liver. 39(2)

Background & aims Replication markers exhibit substantial variation during chronic hepatitis B virus (HBV) infection, part of which can be explained by mutations on the surface (S) gene. We aimed to identify S-gene mutations possibly influencing the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70d65834d0caa696e886375b17b02f4
https://pubmed.ncbi.nlm.nih.gov/30257068

A novel hepatitis B virus (HBV) subgenotype D (D8) strain, resulting from recombination between genotypes D and E, is circulating in Niger along with HBV/E strains

Autor: Aminata Garba, Frédéric Le Gal, Emmanuel Gordien, Mariama Abdou Chekaraou, Wael Y. Mansour, Ségolène Brichler, Paul Dény

Publikováno v: Journal of General Virology. 91:1609-1620

Niger is a west African country that is highly endemic for hepatitis B virus (HBV) infection. The seroprevalence for HBV surface antigen (HBsAg) is about 20%; however, there are no reports on the molecular epidemiology of HBV strains spreading in Nig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c3303c7479d2879a215d4ed4091e94
https://doi.org/10.1099/vir.0.018127-0