Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Mariam R. Khan"'
Autor:
C. Alicia Traughber, Kara Timinski, Ashutosh Prince, Nilam Bhandari, Kalash Neupane, Mariam R. Khan, Esther Opoku, Emmanuel Opoku, Gregory Brubaker, Junchul Shin, Junyoung Hong, Babunageswararao Kanuri, Elif G. Ertugral, Prabhakara R. Nagareddy, Chandrasekhar R. Kothapalli, Olga Cherepanova, Jonathan D. Smith, Kailash Gulshan
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 8 (2024)
Background Pyroptosis executor GsdmD (gasdermin D) promotes atherosclerosis in mice and humans. Disulfiram was recently shown to potently inhibit GsdmD, but the in vivo efficacy and mechanism of disulfiram's antiatherosclerotic activity is yet to be
Externí odkaz:
https://doaj.org/article/15b7d8b60152495897f66b350118e328
Autor:
C. Alicia Traughber, Amanda J. Iacano, Kalash Neupane, Mariam R. Khan, Emmanuel Opoku, Tina Nunn, Ashutosh Prince, Naseer Sangwan, Stanley L. Hazen, Jonathan D. Smith, Kailash Gulshan
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106453- (2023)
Summary: Impavido (Miltefosine) is an FDA-approved drug for treating leishmaniasis and primary amebic meningoencephalitis. We have shown previously that Miltefosine increased cholesterol release and dampened Nlrp3 inflammasome assembly in macrophages
Externí odkaz:
https://doaj.org/article/99e28f8c7c7a4508851f6ba00250eb94
Autor:
C. Alicia Traughber, Gauravi M. Deshpande, Kalash Neupane, Nilam Bhandari, Mariam R. Khan, Megan R. McMullen, Shadi Swaidani, Emmanuel Opoku, Santoshi Muppala, Jonathan D. Smith, Laura E. Nagy, Kailash Gulshan
Publikováno v:
iScience, Vol 26, Iss 2, Pp 106076- (2023)
Summary: The activities of the NLRP3 and AIM2 inflammasomes and Gasdermin D (GsdmD) are implicated in lung cancer pathophysiology but it’s not clear if their contributions promote or retard lung cancer progression. Using a metastatic Lewis lung car
Externí odkaz:
https://doaj.org/article/01281b11f26d44f2bd22e002e5c57436
Autor:
C. Alicia Traughber, Gauravi M Deshpande, Kalash Neupane, Mariam R Khan, Megan R McMullen, Shadi Swaidani, Emmanuel Opoku, Santoshi Muppala, Jonathan D Smith, Laura E Nagy, Kailash Gulshan
The activities of the NLRP3 and AIM2 inflammasomes and Gasdermin D (GsdmD), the final executor of inflammasome activity, are implicated in lung cancer pathophysiology but it’s not clear if their contributions promote or retard lung cancer progressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fe5946ad3a0ee761e072718ed18d430
https://doi.org/10.1101/2022.08.22.504854
https://doi.org/10.1101/2022.08.22.504854
Autor:
C. Alicia Traughber, Amanda J Iacano, Mariam R Khan, Kalash Neupane, Emmanuel Opoku, Tina Nunn, Naseer Sangwan, Stanley L Hazen, Jonathan D Smith, Kailash Gulshan
Excess cholesterol induces foam cell formation, NLRP3 inflammasome activation, and IL-1β release in atherosclerotic plaques. We have shown previously that Miltefosine increased cholesterol release and dampened NLRP3 inflammasome assembly in macropha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbe8bc967a5f7dca1651d52fc0bd796a
https://doi.org/10.1101/2022.08.22.504848
https://doi.org/10.1101/2022.08.22.504848
Autor:
Kailash Gulshan, Amanda J. Iacano, Cynthia A. Traughber, Mariam R. Khan, Emmanuel Opoku, Jonathan D. Smith, Tina Nunn, Naseer Sangwan
Publikováno v:
The FASEB Journal. 36
Autor:
C. Alicia Traughber, Amanda J. Iacano, Mariam R. Khan, Kalash Neupane, Emmanuel Opoku, Tina Nunn, Naseer Sangwan, Stanley L. Hazen, Jonathan Smith, Kailash Gulshan
Publikováno v:
SSRN Electronic Journal.