Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mariam Orme"'
Autor:
Iván Plaza-Menacho, Karin Barnouin, Rachael Barry, Annabel Borg, Mariam Orme, Rakhee Chauhan, Stephane Mouilleron, Rubén J. Martínez-Torres, Pascal Meier, Neil Q. McDonald
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3319-3332 (2016)
Receptor tyrosine kinases exhibit a variety of activation mechanisms despite highly homologous catalytic domains. Such diversity arises through coupling of extracellular ligand-binding portions with highly variable intracellular sequences flanking th
Externí odkaz:
https://doaj.org/article/d79f670d6e0b48388c49a0287b96fbce
Autor:
Pascal Meier, Rachael Barry, Ivan Plaza-Menacho, Stephane Mouilleron, Neil Q. McDonald, Mariam Orme, Annabel Borg, Rubén J. Martínez-Torres, Rakhee Chauhan, Karin Barnouin
Publikováno v:
Cell Reports, Vol 17, Iss 12, Pp 3319-3332 (2016)
Cell Reports
Cell Reports
Summary Receptor tyrosine kinases exhibit a variety of activation mechanisms despite highly homologous catalytic domains. Such diversity arises through coupling of extracellular ligand-binding portions with highly variable intracellular sequences fla
Publikováno v:
The Journal of Neuroscience. 20:8643-8650
GABACreceptors contain ρ subunits and mediate feedback inhibition from retinal amacrine cells to bipolar cells. We previously identified the cytoskeletal protein MAP1B as a ρ1 subunit anchoring protein. Here, we analyze the structural basis and fun
Autor:
Mariam Orme, Pascal Meier
Publikováno v:
Apoptosis : an international journal on programmed cell death. 14(8)
Regulation of apoptosis is crucial to ensure cellular viability, and failure to do so is linked to several human pathologies. The apoptotic cell death programme culminates in the activation of caspases, a family of highly specific cysteine proteases
Publikováno v:
Experimental cell research. 295(1)
Mutations in APC or in beta-catenin, which are common in colon cancer, lead to constitutive activation of beta-catenin/Tcf-dependent signaling. alpha-Catenin is also found in some colon cancer cell nuclei, and loss of its expression correlates with i