Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Mariam H M, Yousif"'
Autor:
Alyaa Mousa, Abdulaziz Shayea, Mohammed Shaban Nadar, Waleed M. Renno, Mariam H. M. Yousif, Bedoor Qabazard
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 79:1320-1343
Long-term diabetic patients suffer immensely from diabetic neuropathy. This study was designed to investigate the effects of hydrogen sulfide (H2S) on peripheral neuropathy, activation of microglia, astrocytes, and the cascade secretion of proinflamm
Autor:
Saghir Akhtar, Bashayer Al-Zaid, Ahmed Z El-Hashim, Bindu Chandrasekhar, Sreeja Attur, Mariam H M Yousif, Ibrahim F Benter
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132215 (2015)
Cationic polyamidoamine (PAMAM) dendrimers are branch-like spherical polymers being investigated for a variety of applications in nanomedicine including nucleic acid drug delivery. Emerging evidence suggests they exhibit intrinsic biological and toxi
Externí odkaz:
https://doaj.org/article/b91dbb0d9ccc45409a029ce0092c54a9
Autor:
Saghir Akhtar, Bindu Chandrasekhar, Sreeja Attur, Gursev S Dhaunsi, Mariam H M Yousif, Ibrahim F Benter
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141657 (2015)
Transactivation of the epidermal growth factor receptor (EGFR or ErbB) family members, namely EGFR and ErbB2, appears important in the development of diabetes-induced vascular dysfunction. Angiotensin-(1-7) [Ang-(1-7)] can prevent the development of
Externí odkaz:
https://doaj.org/article/c133290b35db4e68aa2f3e080bf07c45
Autor:
Hussa, Alshahwan, Bedoor, Qabazard, Alyaa, Mousa, Bindu, Chandrasekhar, Krishna, Santhosh, Mariam H M, Yousif
Publikováno v:
European Journal of Pharmacology. 933:175265
Hydrogen sulfide (Hthe effects of chronic treatment of diabetic rats with GYY4137 (slow releasing Hdiabetes was induced by a single intraperitoneal (ip) injection of streptozotocin (STZ; 55 mg/kg). Sprague Dawley (SD; n = 10-12/group) rats were rando
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 138, Iss, Pp 111486-(2021)
Erectile dysfunction (ED) is a common diabetic complication. Recent evidence has illuminated the role of hydrogen sulfide (H2S) as a dynamic mediator of the erection process. H2S is a potent endogenous relaxant gas. It has been shown to relax human a
Publikováno v:
Journal of Diabetes Research, Vol 2014 (2014)
Angiotensin-(1-7) [Ang-(1-7)] may have beneficial effects in diabetes mellitus-induced erectile dysfunction (DMIED) but its molecular actions in the diabetic corpus cavernosum (CC) are not known. We characterized the effects of diabetes and/or chroni
Externí odkaz:
https://doaj.org/article/013eab296e8f48acba85fcb42839e79f
Autor:
Saghir Akhtar, Mariam H M Yousif, Gursev S Dhaunsi, Fatma Sarkhouh, Bindu Chandrasekhar, Sreeja Attur, Ibrahim F Benter
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e67813 (2013)
Diabetes mellitus leads to vascular complications but the underlying signalling mechanisms are not fully understood. Here, we examined the role of ErbB2 (HER2/Neu), a transmembrane receptor tyrosine kinase of the ErbB/EGFR (epidermal growth factor re
Externí odkaz:
https://doaj.org/article/9828ec605115477086f99b23630bf5c1
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39066 (2012)
This study characterized the effects of diabetes and/or ischemia on epidermal growth factor receptor, EGFR, and/or erbB2 signaling pathways on cardiac function. Isolated heart perfusion model of global ischemia was used to study the effect of chronic
Externí odkaz:
https://doaj.org/article/63c540eb05354aab8496fdad745a5dde
Publikováno v:
International Journal of Impotence Research. 31:111-118
GYY4137 is a novel hydrogen sulfide (H2S) releasing molecule with vasodilator activity. The objectives of this study were to investigate: (1) the pharmacological effect of GYY4137 on the reactivity of the corpus cavernosum (CC) from normal and diabet
Publikováno v:
Peptides. 90:10-16
Angiotensin-(1–7) [Ang-(1–7)] exhibits blood pressure lowering actions, inhibits cell growth, and reduces tissue inflammation and fibrosis which may functionally antagonize an activated Ang II-AT(1) receptor axis. Since the vascular actions of An