Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Mariah M. Hoffman"'
Autor:
Shanta M. Messerli, Mariah M. Hoffman, Etienne Z. Gnimpieba, Hella Kohlhof, Ratan D. Bhardwaj
Publikováno v:
Brain Sciences, Vol 7, Iss 11, p 147 (2017)
This project involves an examination of the effect of the small molecule inhibitor 4SC-202 on the growth of the pediatric brain cancer medulloblastoma. The small molecule inhibitor 4SC-202 significantly inhibits the viability of the pediatric desmopl
Externí odkaz:
https://doaj.org/article/af96d1e2a2cb4a708c608011313a8fcb
Novel discoveries involving the evaluation of potential therapeutics are based on newly identified molecular targets for atypical teratoid rhabdoid tumors (ATRT), which are the most common form of infantile brain tumors. Central nervous system ATRTs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00313ca2107fde3736b8b4b520987d79
https://doi.org/10.1158/1541-7786.c.6541314
https://doi.org/10.1158/1541-7786.c.6541314
Supplementary Fig. S4. PTK7 is structurally similar to receptors that bind Vatalanib. A) Stitch 5.0 network centered around Vatalanib (5) shows proteins that have been identified to interact with Vatalanib. Supplementary Table 1. The GenesLikeMe func
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86877be47bc1318cfd1e0b357a210801
https://doi.org/10.1158/1541-7786.22516224.v1
https://doi.org/10.1158/1541-7786.22516224.v1
Autor:
Jessica L. S. Zylla, Mariah M. Hoffman, Simona Plesselova, Somshuvra Bhattacharya, Kristin Calar, Yohannes Afeworki, Pilar de la Puente, Etienne Z. Gnimpieba, W. Keith Miskimins, Shanta M. Messerli
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1753
This study investigates the effects of a dual selective Class I histone deacetylase (HDAC)/lysine-specific histone demethylase 1A (LSD1) inhibitor known as 4SC-202 (Domatinostat) on tumor growth and metastasis in a highly metastatic murine model of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f40f65ffdf1daeab566f21480d0e545
https://pubmed.ncbi.nlm.nih.gov/35406526
https://pubmed.ncbi.nlm.nih.gov/35406526
Autor:
Jessica L.S. Zylla, Mariah M. Hoffman, Somshuvra Bhattacharya, Kristin Calar, Yohannes Afeworki, Pilar de la Puente, Etienne Z. Gnimpieba, W. Keith Miskimins, Shanta M. Messerli
*denotes Co-First Authorship SuppFile1_MethodsandFigures.docx:Supplementary File 1 Methods and Figures;Full bioinformatics methods and supplementary figures.,SuppFile2_DAVID_4SCvsControl_70DEGs.xlsx;DAVID Annotation 4SC-202 vs Control 70 DEGs:Full fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58807b498811c95407f5d2f078ba9994
Autor:
Mariah M. Hoffman, Kristin Calar, Pilar de la Puente, W. Keith Miskimins, Timothy W. Hartman, Ratan D. Bhardwaj, Jessica S. Zylla, Somshuvra Bhattacharya, Etienne Z. Gnimpieba, Shanta M. Messerli
Publikováno v:
Cancers
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 756 (2020)
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 756 (2020)
Central nervous system atypical teratoid/rhabdoid tumors (ATRTs) are rare and aggressive tumors with a very poor prognosis. Current treatments for ATRT include resection of the tumor, followed by systemic chemotherapy and radiation therapy, which hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::798ac511ab59c5b5752434e9d84727bc
Autor:
Eric J. Dufek, Madhubabu Alaparthi, Andrew G. Sykes, Kadarkaraisamy Mariappan, Mariah M. Hoffman
Publikováno v:
RSC Advances. 6:11295-11302
A new mechanism for the fluorescence detection of metal cations in solution is introduced involving a unique keto–enol tautomerization. Reduction of 1,8-anthraquinone-18-crown-5 yields the doubly reduced secondary alcohol, 2. Compound 2 acts as a c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::83ce84630ae531ee16e0d17fbf197394
https://doi.org/10.1039/c5ra23937k
https://doi.org/10.1039/c5ra23937k
Autor:
Keith Miskimins, Mariah M. Hoffman, Etienne Z. Gnimpieba, Jessica S. Zylla, Shanta M. Messerli
Publikováno v:
Cancer Research. 80:1761-1761
This study examines the effects of the epigenetic modulator 4SC-202, a dual histone deacetylase (HDAC) /lysine-specific histone demethylase 1A (LSD1) small molecule inhibitor, on tumor growth and metastasis in a mouse model of breast cancer. 4SC-202
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aa326d99bfaccbfe959fdf63044bfc4
https://doi.org/10.1158/1538-7445.am2020-1761
https://doi.org/10.1158/1538-7445.am2020-1761
Autor:
Kadarkaraisamy Mariappan, Janani Sindhu Ragothaman, Madhubabu Alaparthi, Andrew G. Sykes, Vinothini Balasubramanian, Mariah M. Hoffman
Publikováno v:
Inorganica Chimica Acta. 429:46-50
The reaction of the Ph2As− anion with 1,8-bis(2-bromoethoxy)anthracene-9,10-dione in 2:1 ratio generates 1,8-bis(2-diphenylarsinoethoxy)anthracene-9,10-dione (L1). L1 and 1,8-bis(2-phenylselenoethoxy)anthraquinone (L2) reacted with bis(benzonitrile
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd4b0d3e5ea8c2a80d8660d72a5441b9
https://doi.org/10.1016/j.ica.2014.12.028
https://doi.org/10.1016/j.ica.2014.12.028
Autor:
Shanta M. Messerli, Etienne Z. Gnimpieba, Ratan D. Bhardwaj, Mariah M. Hoffman, Carrie J. Minette
Publikováno v:
BIBM
The NanoString nCounter Analysis System is a medium-throughput gene expression quantification technique that is becoming increasingly popular in the fields of immunology and oncology due to its ease of use and sensitivity, particularly in the analysi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d6538e76ddfb8ba6690bb7037fe5ef8
https://doi.org/10.1109/bibm.2017.8217992
https://doi.org/10.1109/bibm.2017.8217992