Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Mariah H Klunk"'
Autor:
Alvaro A Ordonez, Supriya Pokkali, Sunhwa Kim, Brian Carr, Mariah H Klunk, Leah Tong, Vikram Saini, Yong S Chang, Matthew McKevitt, Victoria Smith, David L Gossage, Sanjay K Jain
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197474 (2018)
Matrix metalloproteinase (MMP)-9 is a zinc-dependent protease associated with early immune responses to Mycobacterium tuberculosis infection, macrophage recruitment and granuloma formation. We evaluated whether adjunctive inhibition of MMP-9 could im
Externí odkaz:
https://doaj.org/article/54b3f2022fb249b6970c61b92e430123
Autor:
Sanjay K. Jain, Filipa Mota, Camilo A. Ruiz-Bedoya, Mariah H. Klunk, Alvaro A. Ordonez, Joel S. Freundlich, Ravindra Jadhav
Publikováno v:
ACS Infectious Diseases. 6:916-921
Oxazolidinones are a novel class of antibacterials with excellent activity against resistant Gram-positive bacteria including strains causing multidrug-resistant tuberculosis (TB). Despite their ex...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::703af2b8f63c624aa9216158c7ce64a1
https://doi.org/10.1021/acsinfecdis.9b00473
https://doi.org/10.1021/acsinfecdis.9b00473
Autor:
Sanjay K. Jain, Eric O. Aboagye, Babak Benham Azad, Sudhanshu Abhishek, Alok Kumar Singh, Laurence Carroll, Alvaro A. Ordonez, Mariah H. Klunk
Publikováno v:
Mol Imaging Biol
Purpose Despite recent advances in antimicrobial treatments, tuberculosis (TB) remains a major global health threat. Mycobacterium tuberculosis proliferates in macrophages, preventing apoptosis by inducing anti-apoptotic proteins leading to necrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29e7fde4d2e82299b63495c32801e1d4
https://doi.org/10.1007/s11307-020-01494-9
https://doi.org/10.1007/s11307-020-01494-9
Autor:
Takahiro Higuchi, Alvaro A. Ordonez, Donika Plyku, Camilo A. Ruiz-Bedoya, Rudolf A. Werner, Sanjay K. Jain, Robert F. Dannals, Wojciech G. Lesniak, Daniel P. Holt, Jeffrey P. Leal, Mariah H. Klunk, Steven P. Rowe
Publikováno v:
J Nucl Med
para-Aminobenzoic acid (PABA) has been previously used as an exogenous marker to verify completion of 24-h urine sampling. Therefore, we hypothesized that PABA radiolabeled with (11)C might allow high-quality dynamic PET of the kidneys with less radi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::146fcc0121c9acb2c1a23b388d0b07e1
https://doi.org/10.2967/jnumed.119.239806
https://doi.org/10.2967/jnumed.119.239806
Autor:
Sanjay K. Jain, Mariah H. Klunk, Alvaro A. Ordonez, Filipa Mota, Ronnie C. Mease, Alok Kumar Singh, Laurence Carroll, Sudhanshu Abhishek, Camilo A. Ruiz-Bedoya, Joel S. Freundlich
Publikováno v:
ACS Infect Dis
Bedaquiline is a promising drug against tuberculosis (TB), but limited data are available on its intralesional pharmacokinetics. Moreover, current techniques rely on invasive tissue resection, which is difficult in humans and generally limited even i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fff2240e273f4283a706c50344c1967
https://doi.org/10.1021/acsinfecdis.9b00207
https://doi.org/10.1021/acsinfecdis.9b00207
Autor:
Sanjay K. Jain, Alvaro A. Ordonez, B. G. Kang, S. Krug, William R. Bishai, Valina L. Dawson, Mariah H. Klunk, Ted M. Dawson
Tuberculosis (TB) is a devastating infectious disease responsible for nearly 2 million deaths annually that has a poorly understood male bias. Elucidating the basis of this male bias may enable precision medicine interventions for TB treatment and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::508a8e3e3b6fc6fce5bddc1638c03846
https://doi.org/10.1101/2021.04.21.440820
https://doi.org/10.1101/2021.04.21.440820
Autor:
Oren, Gordon, Robert J, Miller, John M, Thompson, Alvaro A, Ordonez, Mariah H, Klunk, Dustin A, Dikeman, Daniel P, Joyce, Camilo A, Ruiz-Bedoya, Lloyd S, Miller, Sanjay K, Jain
Publikováno v:
Disease Models & Mechanisms
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Post-surgical implant-associated spinal infection is a devastating complication commonly caused by Staphylococcus aureus. Biofilm formation is thought to reduce penetration of antibiotics and immune cells, contributing to chronic and difficult-to-tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::636a289f4d075984ed6fdc236c42afdf
https://pubmed.ncbi.nlm.nih.gov/32586832
https://pubmed.ncbi.nlm.nih.gov/32586832
Autor:
Filipa, Mota, Ravindra, Jadhav, Camilo A, Ruiz-Bedoya, Alvaro A, Ordonez, Mariah H, Klunk, Joel S, Freundlich, Sanjay K, Jain
Publikováno v:
ACS Infect Dis
Oxazolidinones are a novel class of antibacterials with excellent activity against resistant Gram-positive bacteria including strains causing multidrug-resistant tuberculosis (TB). Despite their excellent efficacy, optimal dosing strategies to limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::af356d4fce1bd0eb2fb3d6289fe82c7f
https://pubmed.ncbi.nlm.nih.gov/32243132
https://pubmed.ncbi.nlm.nih.gov/32243132
Autor:
Alvaro A. Ordonez, Robert J. Miller, John M. Thompson, Sanjay K. Jain, Lloyd S. Miller, Dustin Dikeman, Mariah H. Klunk, Oren Gordon, Camilo A. Ruiz-Bedoya, Daniel P. Joyce
Publikováno v:
Disease Models & Mechanisms, Vol 13, Iss 7 (2020)
Post-surgical implant-associated spinal infection is a devastating complication commonly caused by Staphylococcus aureus. Biofilm formation is thought to reduce penetration of antibiotics and immune cells, contributing to chronic and difficult-to-tre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d5357bab07d0f273d4dedb9acb95fab
https://doi.org/10.1242/dmm.045385
https://doi.org/10.1242/dmm.045385
Autor:
Sanjay K. Jain, Catherine A. Foss, Mariah H. Klunk, Alvaro A. Ordonez, Julian Sanchez-Bautista
Publikováno v:
Molecular Imaging and Biology. 21:228-231
Foreign body reactions elicit granulomatous inflammation composed of reactive macrophages. We hypothesized that [125I]iodo-DPA-713 single-photon emission computed tomography (SPECT), a low-molecular-weight pyrazolopyrimidine ligand selectively trappe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5301417e81cace719e33d704e64891c0
https://doi.org/10.1007/s11307-018-1249-0
https://doi.org/10.1007/s11307-018-1249-0