Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Mariagiuseppa Matera"'
Autor:
Alessia Bertolotti, Angelo Kaplan, Giulia Tonini, Angela Capriati, Andrea Pellacani, Cristina Rossi, Mariagiuseppa Matera, Giancarlo Pruneri, Giovanna Garzone, Christian Rohlff, Cecilia Simonelli, Vanessa Bussolo, Simona Massa, Monica Binaschi, Giuseppe Merlino, Rosalin Dolores Spagnuolo, Maria Luisa Carcangiu, Serena Buontempo, Valentina Fedi, Paola Collini
Publikováno v:
Journal of Clinical Oncology. 37:e14726-e14726
e14726 Background: CD205 is a type I transmembrane surface protein belonging to the mannose receptor family with propensity for antigen uptake/internalization. CD205 is expressed in different cancer histotypes and seems to have a role in migration an
Autor:
Abrahim Fandi, D'Angiolella Paola, Giulia Tonini, Elena Garralda, Elizabeth Ruth Plummer, Michele Spina, Guy Jerusalem, Mario Cioce, Paolo Mazzei, Cecilia Simonelli, Serena Buontempo, Giuseppe Merlino, Josep Tabernero, Monica Binaschi, Victor Moreno Garcia, Andrea Pellacani, Cristina Rossi, Mariagiuseppa Matera, Christian Rohlff, Maria de Miguel
Publikováno v:
Journal of Clinical Oncology. 36:TPS2606-TPS2606
TPS2606Background: MEN1309/OBT076 is a DM4-loaded Antibody Drug Conjugate (ADC), directed against CD205/Ly75, a type I transmembrane surface protein belonging to the macrophage mannose receptor fam...
Autor:
Giuseppe Petrosillo, Nicola Moro, Francesca Maria Ruggiero, Mariagiuseppa Matera, Giuseppe Paradies
Publikováno v:
Free Radical Biology and Medicine. 46:88-94
Reactive oxygen species (ROS) are considered a key factor in the heart aging process. Mitochondrial respiration is an important site of ROS generation and a potential contributor to heart functional changes with aging. We have examined the effects of
Autor:
Giuseppe Paradies, Carlo Bertoni-Freddari, Giuseppe Petrosillo, Patrizia Fattoretti, Francesca Maria Ruggiero, Mariagiuseppa Matera
Publikováno v:
Rejuvenation Research. 11:935-943
Reactive oxygen species (ROS) are considered a key factor in brain aging process. Complex I of the mitochondrial respiration chain is an important site of ROS production and hence a potential contributor to brain functional changes with aging. Approp
Autor:
Domenico Ferri, Giuseppe Petrosillo, Ignazio Grattagliano, Giuseppe Paradies, Mariagiuseppa Matera, Piero Portincasa, Giacoma Casanova, Francesca Maria Ruggiero
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1767(10):1260-1267
Mitochondrial dysfunction and oxidative stress play a central role in the pathophysiology of nonalcoholic fatty liver disease (NAFLD). This study aimed to elucidate the mechanism(s) responsible for mitochondrial dysfunction in nonalcoholic fatty live
Autor:
Giuseppe Petrosillo, Giuseppe Paradies, Francesca Maria Ruggiero, Giacoma Casanova, Mariagiuseppa Matera
Publikováno v:
FEBS Letters. 580:6311-6316
Cardiolipin peroxidation plays a critical role in mitochondrial cytochrome c release and subsequent apoptotic process. Mitochondrial pore transition (MPT) is considered as an important step in this process. In this work, the effect of peroxidized car
Autor:
Monica Binaschi, Andrea Pellacani, Mario Bigioni, Rachel L. Dusek, Angelo Kaplan, Nickolas Attanasio, Christian Rohlff, Michele Spina, Valter Gattei, Merlino Giuseppe, Valentina Fedi, Cecilia Simonelli, Annalisa Polizzi-Anselmo, Mariagiuseppa Matera, Vincenzo Canzonieri, Silvia Manunta
Publikováno v:
Journal of Clinical Oncology. 35:e14039-e14039
e14039 Background: CD205 is a type I C-type lectin receptor normally expressed on various APC and some leukocyte sub-populations, characterized by a cytoplasmic domain containing protein motifs crucial for endocytosis and internalization. These featu
Autor:
Giuseppe, Petrosillo, Giacoma, Casanova, Mariagiuseppa, Matera, Francesca Maria, Ruggiero, Giuseppe, Paradies
Publikováno v:
The Italian journal of biochemistry. 56(4)
The effect of peroxidized cardiolipin on the mitochondrial pore transition (MPT) induction and cytochrome c release in rat heart mitochondria was studied. Treatment of mitochondria with cardiolipin hydroperoxide (CLOOH) promoted matrix swelling and r
Autor:
Giuseppe, Petrosillo, Piero, Portincasa, Ignazio, Grattagliano, Giacoma, Casanova, Mariagiuseppa, Matera, Francesca M, Ruggiero, Domenico, Ferri, Giuseppe, Paradies
Publikováno v:
Biochimica et biophysica acta. 1767(10)
Mitochondrial dysfunction and oxidative stress play a central role in the pathophysiology of nonalcoholic fatty liver disease (NAFLD). This study aimed to elucidate the mechanism(s) responsible for mitochondrial dysfunction in nonalcoholic fatty live
Autor:
Dimitri Breems, Mariagiuseppa Matera, Paolo Mazzei, Angela Capriati, Eugen Leo, Monica Binaschi, Alessandra Scordari, Carlo Alberto Maggi, Violaine Havelange, Cecilia Simonelli, Simona Scartoni, Attilio Crea, Stefano Manzini, Cristina Rossi, Adriano Venditti, Keith G. Wilson, Giovanni Martinelli, Giulia Tonini, Simone Baldini
Publikováno v:
Journal of Clinical Oncology. 33:TPS3100-TPS3100
TPS3100 Background: Defucosylated mAbs enhance antibody dependent cell-mediated cytotoxicity (ADCC) through an improved affinity for Fc receptors. MEN1112/OBT357 is a humanized, defucosylated mAb t...