Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Mariacristina Capizzi"'
Publikováno v:
Cell Reports. 40:111261
Compelling evidence indicates that in Huntington's disease (HD), mutation of huntingtin (HTT) alters several aspects of early brain development such as synaptogenesis. It is not clear to what extent the partial loss of wild-type HTT function contribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a3dd04fe1f30104eb29b373d86845d
https://doi.org/10.1016/j.celrep.2022.111261
https://doi.org/10.1016/j.celrep.2022.111261
Autor:
Mariacristina Capizzi, Rémi Carpentier, Yohann Couté, Rayane Kassem, Eric Denarier, Annie Adrait, Marina Mapelli, Sandrine Humbert
Publikováno v:
Neuron
Neuron, 2022, 110 (1), pp.36-50.e5. ⟨10.1016/j.neuron.2021.10.033⟩
Neuron, 2022, 110 (1), pp.36-50.e5. ⟨10.1016/j.neuron.2021.10.033⟩
Summary Although the classic symptoms of Huntington’s disease (HD) manifest in adulthood, neural progenitor cell behavior is already abnormal by 13 weeks’ gestation. To determine how these developmental defects evolve, we turned to cell and mouse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7755900681ae58e00c049d879fccd6a6
https://doi.org/10.1016/j.neuron.2021.10.033
https://doi.org/10.1016/j.neuron.2021.10.033
Autor:
Sophie Lenoir, Scott Zeitlin, Susana Boluda, Mariacristina Capizzi, Radhia Kacher, Sandrine Humbert, Barbara Y. Braz, Alexandra Durr, Charles Duyckaerts, Doris Wennagel, Rayane Kassem, Marc Dommergues, Fabienne Agasse, Esther Aparicio, Monia Barnat, Aude Tessier, Jeh-Ping Liu, Julien Ighil
Publikováno v:
Science
Although Huntington’s disease is a late-manifesting neurodegenerative disorder, both mouse studies and neuroimaging studies of presymptomatic mutation carriers suggest that Huntington’s disease might affect neurodevelopment. To determine whether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47eb88182a4124a101675dffc5626b9e
https://pubmed.ncbi.nlm.nih.gov/32908281
https://pubmed.ncbi.nlm.nih.gov/32908281
Autor:
Mariacristina Capizzi, Valentina Cianfanelli, Francesco Cecconi, Elena Papaleo, Flavie Strappazzon
Publikováno v:
Autophagy. 13(3)
Macroautophagy/autophagy is a tightly regulated intracellular catabolic pathway involving the lysosomal degradation of cytoplasmic organelles and proteins to be recycled into metabolic precursors. AMBRA1 (autophagy and Beclin 1 regulator 1) has a cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07efaa10f60ef23f522fb5c11f89a0f5
https://pubmed.ncbi.nlm.nih.gov/28059583
https://pubmed.ncbi.nlm.nih.gov/28059583