Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Mariaclara Iaselli"'
Autor:
Morena Miciaccia, Benny Danilo Belviso, Mariaclara Iaselli, Gino Cingolani, Savina Ferorelli, Marianna Cappellari, Paola Loguercio Polosa, Maria Grazia Perrone, Rocco Caliandro, Antonio Scilimati
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract The beneficial effects of Cyclooxygenases (COX) inhibitors on human health have been known for thousands of years. Nevertheless, COXs, particularly COX-1, have been linked to a plethora of human diseases such as cancer, heart failure, neurol
Externí odkaz:
https://doaj.org/article/e348145f07bc4650920473b1d5b3a4fd
Autor:
Lukas Friedrich, Gino Cingolani, Ying‐Hui Ko, Mariaclara Iaselli, Morena Miciaccia, Maria Grazia Perrone, Konstantin Neukirch, Veronika Bobinger, Daniel Merk, Robert Klaus Hofstetter, Oliver Werz, Andreas Koeberle, Antonio Scilimati, Gisbert Schneider
Publikováno v:
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Abstract The repertoire of natural products offers tremendous opportunities for chemical biology and drug discovery. Natural product‐inspired synthetic molecules represent an ecologically and economically sustainable alternative to the direct utili
Externí odkaz:
https://doaj.org/article/d4a04b893ed549168e9964a291c5d478
Autor:
Paola Loguercio Polosa, Mariaclara Iaselli, Maria Grazia Perrone, Antonio Scilimati, Morena Miciaccia, Savina Ferorelli
Publikováno v:
Current Enzyme Inhibition. 18:2-9
Background: Recent findings enlightened the pivotal role of cyclooxygenases-1 and -2 (COX-1 and COX-2) in human diseases with inflammation as the committed earliest stage, such as cancer and neurodegenerative diseases. COXs are the main targets of no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03f16bacaad768d94839dfd40a0c858c
https://doi.org/10.2174/1573408017666211108104731
https://doi.org/10.2174/1573408017666211108104731
Autor:
Veronika Bobinger, Morena Miciaccia, Ying-Hui Ko, Mariaclara Iaselli, Gino Cingolani, Robert Klaus Hofstetter, Oliver Werz, Gisbert Schneider, Maria Grazia Perrone, Konstantin Neukirch, Daniel Merk, Antonio Scilimati, Andreas Koeberle, Lukas Friedrich
Publikováno v:
Advanced Science, 8 (16)
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Advanced Science
Advanced Science, Vol 8, Iss 16, Pp n/a-n/a (2021)
Advanced Science
The repertoire of natural products offers tremendous opportunities for chemical biology and drug discovery. Natural product-inspired synthetic molecules represent an ecologically and economically sustainable alternative to the direct utilization of n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0567a21d00edccbddd812504cbd3c57b
Autor:
Morena Miciaccia, Savina Ferorelli, Giuseppe Di Mauro, Luiz Cláudio Rodrigues Pereira da Silva, Thaisa Francielle Souza Domingos, Angelo Vacca, Antonio Scilimati, Cosimo G. Fortuna, Mariaclara Iaselli, Paola Vitale, Angelina Boccarelli, Marcelo de Pádula, Maria Grazia Perrone, Maria Laura Pati, Plínio Cunha Sathler, Lucio Mendes Cabral
A set of novel diarylisoxazoles has been projected using mofezolac (1) as a lead compound to investigate structure-inhibitory activity relationships of new compounds and the cyclooxygenases (COXs) catalytic activity. Mofezolac was chosen because is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0658dc3f720b49cea9219a3ce8dfc157
http://hdl.handle.net/20.500.11769/364452
http://hdl.handle.net/20.500.11769/364452