Výsledky vyhledávání - "Maria-Pilar Giner"

Akademický článek

Nicotinamide riboside kinases regulate skeletal muscle fiber-type specification and are rate-limiting for metabolic adaptations during regeneration

Autor: Tanja Sonntag, Sara Ancel, Sonia Karaz, Paulina Cichosz, Guillaume Jacot, Maria Pilar Giner, José Luis Sanchez-Garcia, Alice Pannérec, Sofia Moco, Vincenzo Sorrentino, Carles Cantó, Jérôme N. Feige

Publikováno v: Frontiers in Cell and Developmental Biology, Vol 10 (2022)

Nicotinamide riboside kinases (NRKs) control the conversion of dietary Nicotinamide Riboside (NR) to NAD+, but little is known about their contribution to endogenous NAD+ turnover and muscle plasticity during skeletal muscle growth and remodeling. Us

Externí odkaz: https://doaj.org/article/5253b06c050f404a8ef8de116a0b4bf0

Zobrazit plný text záznamu

Akademický článek

Mitochondrial oxidative capacity and NAD+ biosynthesis are reduced in human sarcopenia across ethnicities

Publikováno v: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)

Sarcopenia is the loss of muscle mass and strength associated with physical disability during ageing. Here, the authors analyse muscle biopsies from 119 patients with sarcopenia and age-matched controls of different ethnic groups and find transcripti

Externí odkaz: https://doaj.org/article/4c3223da69ca4524955a319f2fa0179d

Zobrazit plný text záznamu

Akademický článek

A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor

Autor: Judith Giroud-Gerbetant, Magali Joffraud, Maria Pilar Giner, Angelique Cercillieux, Simona Bartova, Mikhail V. Makarov, Rubén Zapata-Pérez, José L. Sánchez-García, Riekelt H. Houtkooper, Marie E. Migaud, Sofia Moco, Carles Canto

Publikováno v: Molecular Metabolism, Vol 30, Iss , Pp 192-202 (2019)

Objective: A decay in intracellular NAD+ levels is one of the hallmarks of physiological decline in normal tissue functions. Accordingly, dietary supplementation with NAD+ precursors can prevent, alleviate, or even reverse multiple metabolic complica

Externí odkaz: https://doaj.org/article/6c4c170dedb84391bff1d462c0934a35

Zobrazit plný text záznamu

Akademický článek

Nicotinamide Riboside and Dihydronicotinic Acid Riboside Synergistically Increase Intracellular NAD+ by Generating Dihydronicotinamide Riboside

Autor: Eleonora Ciarlo, Magali Joffraud, Faisal Hayat, Maria Pilar Giner, Judith Giroud-Gerbetant, Jose Luis Sanchez-Garcia, Marie Rumpler, Sofia Moco, Marie E. Migaud, Carles Cantó

Publikováno v: Nutrients, Vol 14, Iss 13, p 2752 (2022)

Through evolution, eukaryote organisms have developed the ability to use different molecules as independent precursors to generate nicotinamide adenine dinucleotide (NAD+), an essential molecule for life. However, whether these different precursors a

Externí odkaz: https://doaj.org/article/8bc026fc60e043df9e5a89cef79de1b8

Zobrazit plný text záznamu

Akademický článek

A Method to Monitor the NAD+ Metabolome—From Mechanistic to Clinical Applications

Autor: Maria Pilar Giner, Stefan Christen, Simona Bartova, Mikhail V. Makarov, Marie E. Migaud, Carles Canto, Sofia Moco

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 19, p 10598 (2021)

Nicotinamide adenine dinucleotide (NAD+) and its reduced form (NADH) are coenzymes employed in hundreds of metabolic reactions. NAD+ also serves as a substrate for enzymes such as sirtuins, poly(ADP-ribose) polymerases (PARPs) and ADP-ribosyl cyclase

Externí odkaz: https://doaj.org/article/0820e414ecc345bd87701d172f06110c

Zobrazit plný text záznamu

Plný text ve formátu HTML

A reduced form of nicotinamide riboside defines a new path for NAD+ biosynthesis and acts as an orally bioavailable NAD+ precursor

Autor: Marie E. Migaud, Maria Pilar Giner, Angelique Cercillieux, Judith Giroud-Gerbetant, Carles Cantó, Magali Joffraud, Riekelt H. Houtkooper, Mikhail V. Makarov, Rubén Zapata-Pérez, Simona Bartova, Sofia Moco, Jose L. Sanchez-Garcia

Publikováno v: Molecular Metabolism, Vol 30, Iss, Pp 192-202 (2019)
Molecular metabolism, 30, 192-202. Elsevier GmbH
Molecular Metabolism

Objective A decay in intracellular NAD+ levels is one of the hallmarks of physiological decline in normal tissue functions. Accordingly, dietary supplementation with NAD+ precursors can prevent, alleviate, or even reverse multiple metabolic complicat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef43ddd49570a1e2401ae3080225ab7b
http://www.sciencedirect.com/science/article/pii/S2212877819309160

Zobrazit plný text záznamu

A method to monitor the NAD+ metabolome—from mechanistic to clinical applications

Autor: Marie E. Migaud, Carles Cantó, Sofia Moco, Mikhail V. Makarov, Maria Pilar Giner, Simona Bartova, Stefan Christen

Publikováno v: Giner, M P, Christen, S, Bartova, S, Makarov, M V, Migaud, M E, Canto, C & Moco, S 2021, ' A method to monitor the NAD + metabolome—from mechanistic to clinical applications ', International Journal of Molecular Sciences, vol. 22, no. 19, 10598, pp. 1-16 . https://doi.org/10.3390/ijms221910598
International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10598, p 10598 (2021)
International Journal of Molecular Sciences, 22(19):10598, 1-16. Multidisciplinary Digital Publishing Institute (MDPI)

Nicotinamide adenine dinucleotide (NAD+) and its reduced form (NADH) are coenzymes employed in hundreds of metabolic reactions. NAD+ also serves as a substrate for enzymes such as sirtuins, poly(ADP‐ribose) polymerases (PARPs) and ADP‐ribosyl cyc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98637fc0a2fd1ab8892636db7e477b4f
https://hdl.handle.net/1871.1/55799f3d-dd72-4eb6-8223-ea102b8d397b

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání