Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Maria-Malvina Tsamouri"'
Autor:
Kimberley D. Katleba, Maria-Malvina Tsamouri, Maitreyee Jathal, Han Bit Baek, Rebecca B. Armenta, Clifford G. Tepper, Gino Cortopassi, Paramita M. Ghosh, Maria Mudryj
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The observed sex disparity in bladder cancer (BlCa) argues that androgen receptor (AR) signaling has a role in these malignancies. BlCas express full-length AR (FL-AR), constitutively active AR splice variants, including AR-v19, or both, and
Externí odkaz:
https://doaj.org/article/808e9dbfa3f84e6190abe7c760f86466
Autor:
Maria Malvina Tsamouri, Blythe P. Durbin-Johnson, William T. N. Culp, Carrie A. Palm, Mamta Parikh, Michael S. Kent, Paramita M. Ghosh
Publikováno v:
Metabolites, Vol 12, Iss 3, p 200 (2022)
Urothelial carcinoma (UC), the most common urologic cancer in dogs, is often diagnosed late because the clinical signs are shared by other non-malignant lower urinary tract disorders (LUTD). The urine-based BRAFV595E test for UC is highly effective o
Externí odkaz:
https://doaj.org/article/a0d0569f783648ea8630fc485b35f6bc
Autor:
Elisabeth A. Messner, Thomas M. Steele, Maria Malvina Tsamouri, Nazila Hejazi, Allen C. Gao, Maria Mudryj, Paramita M. Ghosh
Publikováno v:
Biomedicines, Vol 8, Iss 10, p 422 (2020)
The androgen receptor (AR) plays a predominant role in prostate cancer (PCa) pathology. It consists of an N-terminal domain (NTD), a DNA-binding domain (DBD), a hinge region (HR), and a ligand-binding domain (LBD) that binds androgens, including test
Externí odkaz:
https://doaj.org/article/35004da794404d229d70334322341d91
Publikováno v:
Biomedicines, vol 9, iss 10
Biomedicines
Biomedicines, Vol 9, Iss 1472, p 1472 (2021)
Biomedicines
Biomedicines, Vol 9, Iss 1472, p 1472 (2021)
Muscle-invasive urothelial carcinoma (MIUC) is the most common type of bladder malignancy in humans, but also in dogs that represent a naturally occurring model for this disease. Dogs are immunocompetent animals that share risk factors, pathophysiolo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4451806059ab93d9c05c120d3dc674a2
https://escholarship.org/uc/item/8cd6j0zx
https://escholarship.org/uc/item/8cd6j0zx
Autor:
Thomas M. Steele, Elisabeth A. Messner, Maria Malvina Tsamouri, Salma Siddiqui, Brian Bennion, Ruiwu Liu, Paramita Ghosh
Publikováno v:
Cancer Research. 82:2650-2650
Background: The androgen receptor (AR), which plays a major role in prostate cancer (PCa), consists of a C-terminal ligand-binding domain (LBD), a hinge domain, a DNA-binding domain (DBD), and an N-terminal domain (NTD). Current AR antagonists and AR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f92bc062685a664e8ae940727f6c263a
https://doi.org/10.1158/1538-7445.am2022-2650
https://doi.org/10.1158/1538-7445.am2022-2650
Autor:
Maria Malvina Tsamouri, Salma Siddiqui, Blythe P. Durbin-Johnson, Kit S. Lam, Ruiwu Liu, Paramita M. Ghosh
Publikováno v:
Cancer Research. 82:818-818
Currently, no morphological characteristics have been described in clinical specimens to delineate an androgen receptor (AR)-active from an AR-inactive phenotype in AR-expressing aggressive variant prostate cancer (AVPC). 36 localized and 51 metastat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49779c798373732d4b56fd9f17b516b4
https://doi.org/10.1158/1538-7445.am2022-818
https://doi.org/10.1158/1538-7445.am2022-818
Autor:
Alexander J. Platero, Alan P. Lombard, Maria Mudryj, Paramita M. Ghosh, Ai Hong Ma, Stephen J. Libertini, Kristine S. Nishida, Chong-Xian Pan, Kimberley Katleba, Han Bit Baek, Maria Malvina Tsamouri
Publikováno v:
Cancer Lett
Bladder cancer (BlCa) exhibits a gender disparity where men are three times more likely to develop the malignancy than women suggesting a role for the androgen receptor (AR). Here we report that BlCa cells express low molecular weight (LMW) AR isofor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df581cc7afca6041c7c65a9f5c7d94fb
https://escholarship.org/uc/item/5rn509g0
https://escholarship.org/uc/item/5rn509g0
Autor:
Maria Rapti, George Koukoulis, Charitini Nepka, Maria Malvina Tsamouri, Konstantinos Tsarouhas, Christina Tsitsimpikou, Aristides M. Tsatsakis, Demetrios Kouretas, Paraskevi Kouka, Anestis Soumelidis
Publikováno v:
Food and Chemical Toxicology. 108:186-193
Contrast-induced nephropathy (CIN) is a leading cause of hospital-acquired acute kidney injury as a result of iodinated contrast-media use for diagnostic purposes. Pathophysiology remains unclear. In the present study iopromide was administered to Ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d166295fd03e52ea1909b25b448794de
https://doi.org/10.1016/j.fct.2017.07.058
https://doi.org/10.1016/j.fct.2017.07.058
Autor:
Josephine Skat-Rørdam, Pernille Tveden-Nyborg, Jens Lykkesfeldt, Markus Latta, David Højland Ipsen, Maria Malvina Tsamouri
Publikováno v:
Molecular genetics and genomics : MGG. 294(3)
Hepatic fibrosis increases mortality in humans with non-alcoholic steatohepatitis (NASH), but it remains unclear how fibrosis stage and progression affect the pathogenic mechanisms of NASH. This study investigates the transcriptional regulation and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de6fa181b0808855c9d6718a46fa933
https://pubmed.ncbi.nlm.nih.gov/30759275
https://pubmed.ncbi.nlm.nih.gov/30759275
Autor:
Thomas M. Steele, Maria Malvina Tsamouri, Salma Siddiqui, Christopher A. Lucchesi, Demitria Vasilatis, Benjamin A. Mooso, Blythe P. Durbin-Johnson, Ai-Hong Ma, Nazila Hejazi, Mamta Parikh, Maria Mudryj, Chong-xian Pan, Paramita M. Ghosh
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Cisplatin-based combination chemotherapy is the foundation for treatment of advanced bladder cancer (BlCa), but many patients develop chemoresistance mediated by increased Akt and ERK phosphorylation. However, the mechanism by which cisplati
Externí odkaz:
https://doaj.org/article/e7fd4fc41429405c9cbe1caf0f8d8467