Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Maria-Livia Sassano"'
Autor:
Odeta Meçe, Diede Houbaert, Maria-Livia Sassano, Tania Durré, Hannelore Maes, Marco Schaaf, Sanket More, Maarten Ganne, Melissa García-Caballero, Mila Borri, Jelle Verhoeven, Madhur Agrawal, Kathryn Jacobs, Gabriele Bergers, Silvia Blacher, Bart Ghesquière, Mieke Dewerchin, Johan V. Swinnen, Stefan Vinckier, María S. Soengas, Peter Carmeliet, Agnès Noël, Patrizia Agostinis
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Autophagy is essential to endothelial cell homeostasis. Here the authors show that lipophagy in LEC supports fatty acid oxidation to sustain a mitochondrial-Prox1 gene expression circuit and promote response of LEC to lymphangiogenic mediators.
Externí odkaz:
https://doaj.org/article/6f053768112c4a3e957fc921d9943221
Autor:
Paloma García Casas, Michela Rossini, Linnea Påvénius, Mezida Saeed, Nikita Arnst, Sonia Sonda, Tânia Fernandes, Irene D’Arsiè, Matteo Bruzzone, Valeria Berno, Andrea Raimondi, Maria Livia Sassano, Luana Naia, Elisa Barbieri, Sara Sigismund, Patrizia Agostinis, Mattia Sturlese, Barbara A. Niemeyer, Hjalmar Brismar, Maria Ankarcrona, Arnaud Gautier, Paola Pizzo, Riccardo Filadi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Membrane contact sites (MCSs) are hubs allowing various cell organelles to coordinate their activities. The dynamic nature of these sites and their small size hinder analysis by current imaging techniques. To overcome these limitations, we h
Externí odkaz:
https://doaj.org/article/0b6b5bb0acb9468497829472faf67a2f
Publikováno v:
Contact, Vol 4 (2021)
We recently reported that the ER stress kinase PERK regulates ER-mitochondria appositions and ER– plasma membrane (ER-PM) contact sites, independent of its canonical role in the unfolded protein response. PERK regulation of ER-PM contacts was revea
Externí odkaz:
https://doaj.org/article/4b8cb40e914a445b8dafa682523ff4db
Autor:
Maria Livia Sassano, Alexander R. van Vliet, Ellen Vervoort, Sofie Van Eygen, Chris Van den Haute, Benjamin Pavie, Joris Roels, Johannes V. Swinnen, Marco Spinazzi, Leen Moens, Kristina Casteels, Isabelle Meyts, Paolo Pinton, Saverio Marchi, Leila Rochin, Francesca Giordano, Blanca Felipe-Abrio, Patrizia Agostinis
Publikováno v:
Journal of Cell Biology. 222
The integrity of ER-mitochondria appositions ensures transfer of ions and phospholipids (PLs) between these organelles and exerts crucial effects on mitochondrial bioenergetics. Malfunctions within the ER-mitochondria contacts altering lipid traffick
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::638797bba02da04bf6b363964da2f307
https://doi.org/10.1083/jcb.202206008
https://doi.org/10.1083/jcb.202206008
Publikováno v:
Contact, Vol 1 (2018)
The endoplasmic reticulum (ER) is the most extensive organelle of the eukaryotic cell and constitutes the major site of protein and lipid synthesis and regulation of intracellular Ca 2+ levels. To exert these functions properly, the ER network is sha
Externí odkaz:
https://doaj.org/article/9b8186feff0b46cbac9d65332673e05b
Autor:
Abhishek D. Garg, Sanket More, Nicole Rufo, Odeta Mece, Maria Livia Sassano, Patrizia Agostinis, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi
Publikováno v:
OncoImmunology, Vol 6, Iss 12 (2017)
The expression “immunogenic cell death” (ICD) refers to a functionally unique form of cell death that facilitates (instead of suppressing) a T cell-dependent immune response specific for dead cell-derived antigens. ICD critically relies on the ac
Externí odkaz:
https://doaj.org/article/bba41788dd6d49e3ae68f6677950b756
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
The tight cross talk between two essential organelles of the cell, the endoplasmic reticulum (ER) and mitochondria, is spatially and functionally regulated by specific microdomains known as the mitochondria-associated membranes (MAMs). MAMs are hot s
Externí odkaz:
https://doaj.org/article/566b973ab3ce432c8c744752004fa960
Publikováno v:
Frontiers in Cell and Developmental Biology. 10
Membrane contact sites (MCS) between organelles of eukaryotic cells provide structural integrity and promote organelle homeostasis by facilitating intracellular signaling, exchange of ions, metabolites and lipids and membrane dynamics. Cataloguing MC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44271575cdff800dd411c3a3f96c93b1
https://doi.org/10.3389/fcell.2022.988014
https://doi.org/10.3389/fcell.2022.988014
Autor:
Matteo Rossi, Kristine Rillaerts, Joost van den Oord, Sarah-Maria Fendt, Peter Vangheluwe, Ana Isabel Oliveira, Erminia Romano, Maria Livia Sassano, Vivek Venkataramani, Hannelore Maes, Corentin Schepkens, Johannes V. Swinnen, Jasper Wouters, Bernhard Michalke, Wim Annaert, Massimiliano Mazzone, Chris Van den Haute, Abhishek D. Garg, Francesca Maria Bosisio, Jean-Marie Colet, Patrizia Agostinis, Monica Vara-Perez
Publikováno v:
The EMBO Journal
BNIP3 is a mitophagy receptor with context‐dependent roles in cancer, but whether and how it modulates melanoma growth in vivo remains unknown. Here, we found that elevated BNIP3 levels correlated with poorer melanoma patient’s survival and deple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db8105460bf5b75f4db7cdc6ad825546
https://doi.org/10.15252/embj.2020106214
https://doi.org/10.15252/embj.2020106214
Autor:
Rita Derua, Etienne Waelkens, Maria Livia Sassano, Alexander R. van Vliet, Patrizia Agostinis
We recently reported that the ER stress kinase PERK regulates ER-mitochondria appositions and ER– plasma membrane (ER-PM) contact sites, independent of its canonical role in the unfolded protein response. PERK regulation of ER-PM contacts was revea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135d80eb61b4caaaa355befab9e69e5a
https://lirias.kuleuven.be/handle/20.500.12942/721863
https://lirias.kuleuven.be/handle/20.500.12942/721863
