Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene

Autor: Teppo Varilo, Chris H. Polman, Maria-Liisa Sumelahti, Stacey Gabriel, Anna-Maija Kristiina Sulonen, Arpo Aromaa, David A. Hafler, Pentti J. Tienari, Inger-Lise Mero, Eveliina Jakkula, Stephen L. Hauser, Aarno Palotie, Daniel B. Mirel, Mauri Reunanen, Leena Peltonen, Ludwig Kappos, Shaun Purcell, Annette Bang Oturai, Anu Kemppinen, Helle Bach Søndergaard, Irina Elovaara, Hanne F. Harbo, Philip L. De Jager, Tuula Pirttilä, Keijo Koivisto, Virpi Leppa, Janna Saarela, Mark J. Daly, Suvi P. Kallio

Publikováno v: American journal of human genetics, 86(2), 285-291. Cell Press
Jakkula, E, Leppa, V, Sulonen, A M, Varilo, T, Kallio, S, Kemppinen, A, Purcell, S, Koivisto, K, Tienari, P, Sumelahti, M L, Elovaara, I, Pirttila, T, Reunanen, M, Aromaa, A, Oturai, A B, Sondergaard, H B, Harbo, H F, Mero, I L, Gabriel, S B, Mirel, D B, Hauser, S L, Kappos, L, Polman, C H, de Jager, P L, Hafler, D A, Daly, M J, Palotie, A, Saarela, J & Peltonen, L 2010, ' Genome-wide Association Study in a High-Risk Isolate for Multiple Sclerosis Reveals Associated Variants in STAT3 Gene ', American journal of human genetics, vol. 86, no. 2, pp. 285-291 . https://doi.org/10.1016/j.ajhg.2010.01.017

Genetic risk for multiple sclerosis (MS) is thought to involve both common and rare risk alleles. Recent GWAS and subsequent meta-analysis have established the critical role of the HLA locus and identified new common variants associated to MS. These

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d1ddbb7bb17173c8b5e8e0d4ba16514
https://doi.org/10.1016/j.ajhg.2010.01.017