Zobrazeno 1 - 10
of 136
pro vyhledávání: '"Maria-Isabel Fiel"'
Autor:
Peter G Traber, Hsin Chou, Eliezer Zomer, Feng Hong, Anatole Klyosov, Maria-Isabel Fiel, Scott L Friedman
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e75361 (2013)
Galectin-3 protein is critical to the development of liver fibrosis because galectin-3 null mice have attenuated fibrosis after liver injury. Therefore, we examined the ability of novel complex carbohydrate galectin inhibitors to treat toxin-induced
Externí odkaz:
https://doaj.org/article/e0d5d08b340a46e29da4bcb1bb75acb5
Publikováno v:
JGH Open, Vol 6, Iss 9, Pp 607-611 (2022)
Abstract Background and Aim Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by inflammation and fibrosis of intrahepatic and extrahepatic bile ducts. PSC is frequently associated with inflammatory bowel disea
Externí odkaz:
https://doaj.org/article/cb431e6b674c4c78a1dba1d89480a3e8
Autor:
Dipankar Bhattacharya, Christine Becker, Benjamin Readhead, Nicolas Goossens, Jacqueline Novik, Maria Isabel Fiel, Leslie P. Cousens, Björn Magnusson, Anna Backmark, Ryan Hicks, Joel T. Dudley, Scott L. Friedman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Non-alcoholic steatohepatitis (NASH) is a rising health challenge, with no approved drugs. We used a computational drug repositioning strategy to uncover a novel therapy for NASH, identifying a GABA-B receptor agonist, AZD3355 (Lesogaberan)
Externí odkaz:
https://doaj.org/article/b83db01028b94994911b0442d41b0959
Publikováno v:
Radiology Case Reports, Vol 17, Iss 9, Pp 3452- (2022)
Externí odkaz:
https://doaj.org/article/aa98bdfe4af34c948e073c9ac055b6ed
Publikováno v:
Radiology Case Reports, Vol 16, Iss 1, Pp 84-89 (2021)
Giant pedunculated hepatocellular adenomas are extremely rare tumors and often detected incidentally on cross-sectional imaging studies. We report the case of a 34-year-old woman who underwent cross-sectional imaging for staging evaluation of a uteri
Externí odkaz:
https://doaj.org/article/7ad852d9e7b64afebbfde162b85b45de
Autor:
Sheena Bhalla, Huili Zhu, Jung‐Yi Lin, Umut Özbek, Eric J. Wilck, Sanders Chang, Xiuxu Chen, Stephen Ward, Noam Harpaz, Alexandros D. Polydorides, William Miller, Maria Isabel Fiel, Ippolito Modica, Wen Fan, Nebras Zeizafoun, Celina Ang
Publikováno v:
Cancer Reports, Vol 4, Iss 6, Pp n/a-n/a (2021)
Abstract Background Neoadjuvant chemotherapy (NAC) is frequently used in gastrointestinal cancers (GIC), and pathological, radiological, and tumor marker responses are assessed during and after NAC. Aim To evaluate the relationship between pathologic
Externí odkaz:
https://doaj.org/article/1bdbe2c8a4f84eac9d655c81b2b4d045
Autor:
Svenja Sydor, Paul Manka, Jan Best, Sami Jafoui, Jan-Peter Sowa, Miguel Eugenio Zoubek, Virginia Hernandez-Gea, Francisco Javier Cubero, Julia Kälsch, Diana Vetter, Maria Isabel Fiel, Yujin Hoshida, C. Billie Bian, Leonard J. Nelson, Han Moshage, Klaas Nico Faber, Andreas Paul, Hideo A. Baba, Guido Gerken, Scott L. Friedman, Ali Canbay, Lars P. Bechmann
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Krüppel-like factor 6 (KLF6) is a transcription factor and tumor suppressor. We previously identified KLF6 as mediator of hepatocyte glucose and lipid homeostasis. The loss or reduction of KLF6 is linked to the progression of hepatocellular
Externí odkaz:
https://doaj.org/article/2286249dec7344db8e423965de3b8b26
Autor:
Maria Isabel Fiel, Thomas D. Schiano
Publikováno v:
Surgical Pathology Clinics.
Autor:
Thomas U Marron, Maria Isabel Fiel, Pauline Hamon, Nathalie Fiaschi, Edward Kim, Stephen C Ward, Zhen Zhao, Joel Kim, Paul Kennedy, Ganesh Gunasekaran, Parissa Tabrizian, Deborah Doroshow, Meredith Legg, Ashley Hammad, Assaf Magen, Alice O Kamphorst, Muhammed Shareef, Namita T Gupta, Raquel Deering, Wei Wang, Fang Wang, Pradeep Thanigaimani, Jayakumar Mani, Leanna Troncoso, Alexandra Tabachnikova, Christie Chang, Guray Akturk, Mark Buckup, Steven Hamel, Giorgio Ioannou, Clotilde Hennequin, Hajra Jamal, Haley Brown, Antoinette Bonaccorso, Daniel Labow, Umut Sarpel, Talia Rosenbloom, Max W Sung, Baijun Kou, Siyu Li, Vladimir Jankovic, Nicola James, Sara C Hamon, Hung Kam Cheung, Jennifer S Sims, Elizabeth Miller, Nina Bhardwaj, Gavin Thurston, Israel Lowy, Sacha Gnjatic, Bachir Taouli, Myron E Schwartz, Miriam Merad
Publikováno v:
Lancet Gastroenterol Hepatol
BACKGROUND: Surgical resection of early stage hepatocellular carcinoma is standard clinical practice; however, most tumours recur despite surgery, and no perioperative intervention has shown a survival benefit. Neoadjuvant immunotherapy has induced p
Autor:
Dongwei Zhang, Tanzy Love, Yansheng Hao, Bella Lingjia Liu, Swan Thung, Maria Isabel Fiel, Christa L Whitney-Miller, Xiaoyan Liao
Publikováno v:
American Journal of Clinical Pathology. 158:70-80
Objectives The 8th edition American Joint Committee on Cancer (AJCC) staging system for hepatocellular carcinoma (HCC) has been criticized for failing to stratify patients. We aimed to reassess and modify the tumor staging criteria for HCC. Methods T