Zobrazeno 1 - 10
of 386
pro vyhledávání: '"Maria-Grazia Roncarolo"'
Autor:
Yohei Sato, Abinaya Nathan, Suzette Shipp, John Fraser Wright, Keri Marie Tate, Prachi Wani, Maria-Grazia Roncarolo, Rosa Bacchetta
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 1, Pp 101199- (2024)
Externí odkaz:
https://doaj.org/article/1d7bec4018974d16bc54bd75f1988b02
Autor:
Yohei Sato, Abinaya Nathan, Suzette Shipp, John Fraser Wright, Keri Marie Tate, Prachi Wani, Maria-Grazia Roncarolo, Rosa Bacchetta
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101150- (2023)
Forkhead box P3 (FOXP3) is an essential transcription factor for regulatory T cell (Treg) function. Defects in Tregs mediate many immune diseases including the monogenic autoimmune disease immune dysregulation, polyendocrinopathy, enteropathy, X-link
Externí odkaz:
https://doaj.org/article/4857ed24484f46b1a8ddb706e314c3fb
Autor:
Giada Amodio, Michela Comi, Daniela Tomasoni, Monica Emma Gianolini, Roberta Rizzo, Joël LeMaoult, Maria-Grazia Roncarolo, Silvia Gregori
Publikováno v:
Haematologica, Vol 100, Iss 4 (2015)
Human leukocyte antigen (HLA)-G is a non-classical HLA class I molecule with known immune-modulatory functions. Our group identified a subset of human dendritic cells, named DC-10, that induce adaptive interleukin-10-producing T regulatory type 1 (Tr
Externí odkaz:
https://doaj.org/article/5109db8a36c64926a0731497388e50e7
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Type 1 regulatory T (Tr1) cells, in addition to other regulatory cells, contribute to immunological tolerance to prevent autoimmunity and excessive inflammation. Tr1 cells arise in the periphery upon antigen stimulation in the presence of tolerogenic
Externí odkaz:
https://doaj.org/article/10cb09b9e21941ce84c4fcb94b6f558a
Autor:
Elaine F. Reed, Anita S. Chong, Megan K. Levings, Caley Mutrie, Terri M. Laufer, Maria Grazia Roncarolo, Megan Sykes
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The authors of this article, all women who have been deeply committed to the Federation of Clinical Immunology Societies (FOCIS), performed a retrospective analysis of gender equality practices of FOCIS to identify areas for improvement and make reco
Externí odkaz:
https://doaj.org/article/c66027c8cc2b47e899ca6620e7ae4a8a
Autor:
Mara Pavel-Dinu, Volker Wiebking, Beruh T. Dejene, Waracharee Srifa, Sruthi Mantri, Carmencita E. Nicolas, Ciaran Lee, Gang Bao, Eric J. Kildebeck, Niraj Punjya, Camille Sindhu, Matthew A. Inlay, Nivedita Saxena, Suk See DeRavin, Harry Malech, Maria Grazia Roncarolo, Kenneth I. Weinberg, Matthew H. Porteus
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Gene correction in hematopoietic stem cells could be a powerful way to treat monogenic diseases of the blood and immune system. Here the authors develop a strategy using CRISPR-Cas9 and an aAdeno-Associated vVirus(AAV)-delivered IL2RG cDNA to correct
Externí odkaz:
https://doaj.org/article/66cf921ac2ec4178bebe47ca77ff7c87
Autor:
Leonie Brockmann, Shiwa Soukou, Babett Steglich, Paulo Czarnewski, Lilan Zhao, Sandra Wende, Tanja Bedke, Can Ergen, Carolin Manthey, Theodora Agalioti, Maria Geffken, Oliver Seiz, Sara M. Parigi, Chiara Sorini, Jens Geginat, Keishi Fujio, Thomas Jacobs, Thomas Roesch, Jacob R. Izbicki, Ansgar W. Lohse, Richard A. Flavell, Christian Krebs, Jan-Ake Gustafsson, Per Antonson, Maria Grazia Roncarolo, Eduardo J. Villablanca, Nicola Gagliani, Samuel Huber
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Tr1 cells are considered an immunosuppressive CD4 T cell population producing IL-10. Here the authors show that IL-10 is insufficient for Tr1 immunosuppression, define surface markers and transcriptional program of the immunosuppressive subset within
Externí odkaz:
https://doaj.org/article/9965d7bfb0694a05899ad6316109497d
Autor:
Mark C. Wilkes, Vanessa Scanlon, Aya Shibuya, Alma-Martina Cepika, Ascia Eskin, Zugen Chen, Anupama Narla, Bert Glader, Maria Grazia Roncarolo, Stanley F. Nelson, Kathleen M. Sakamoto
Publikováno v:
Experimental Hematology. 111:66-78
Diamond-Blackfan Anemia (DBA) is an inherited bone marrow failure syndrome that is associated with anemia, congenital anomalies, and cancer predisposition. It is categorized as a ribosomopathy, because more than 80% or patients have haploinsufficienc
Autor:
Alice Bertaina, Maria Grazia Roncarolo
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative therapeutic option for a wide range of immune and hematologic malignant and non-malignant disorders. Once transplanted, allogeneic cells have to support myeloid repopulation and
Externí odkaz:
https://doaj.org/article/f0659acc44c94dd2a899ccb3dd5ef73a
Autor:
Faekah Gohar, Patrick Maschmeyer, Bechara Mfarrej, Mathieu Lemaire, Lucy R. Wedderburn, Maria Grazia Roncarolo, Annet van Royen-Kerkhof
Publikováno v:
Frontiers in Medicine, Vol 6 (2019)
Externí odkaz:
https://doaj.org/article/9988cb60a41942c9bd078bf4f2f3ebda