Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Maria-Eleni Androutsou"'
1
Akademický článek
Maturation of circulating Ly6ChiCCR2+ monocytes by mannan-MOG induces antigen-specific tolerance and reverses autoimmune encephalomyelitis
Autor: Anastasia Dagkonaki, Athina Papalambrou, Maria Avloniti, Areti Gkika, Maria Evangelidou, Maria-Eleni Androutsou, Theodore Tselios, Lesley Probert
Publikováno v: Frontiers in Immunology, Vol 13 (2022)
Autoimmune diseases affecting the CNS not only overcome immune privilege mechanisms that protect neural tissues but also peripheral immune tolerance mechanisms towards self. Together with antigen-specific T cells, myeloid cells are main effector cell
Externí odkaz: https://doaj.org/article/de53e7d0d54a481fb531d2b4f37bc68f
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2
Akademický článek
Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions
Autor: Anastasia Dagkonaki, Maria Avloniti, Maria Evangelidou, Irini Papazian, Ioannis Kanistras, Vivian Tseveleki, Fotis Lampros, Theodore Tselios, Lise Torp Jensen, Wiebke Möbius, Torben Ruhwedel, Maria-Eleni Androutsou, John Matsoukas, Maria Anagnostouli, Hans Lassmann, Lesley Probert
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
CNS autoantigens conjugated to oxidized mannan (OM) induce antigen-specific T cell tolerance and protect mice against autoimmune encephalomyelitis (EAE). To investigate whether OM-peptides treat EAE initiated by human MHC class II molecules, we admin
Externí odkaz: https://doaj.org/article/01e6e4ce64414d3fbec5f23cf0834a95
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3
Akademický článek
Facile and Efficient Syntheses of a Series of N-Benzyl and N-Biphenylmethyl Substituted Imidazole Derivatives Based on (E)-Urocanic acid, as Angiotensin II AT1 Receptor Blockers
Autor: Theodore Tselios, Catherine Koukoulitsa, Demetrios Vlahakos, Panagiotis Plotas, Dimitra Kalavrizioti, Maria-Eleni Androutsou, Amalia Resvani, Konstantinos Kelaidonis, George Agelis, Thomas Mavromoustakos, John Matsoukas
Publikováno v: Molecules, Vol 18, Iss 7, Pp 7510-7532 (2013)
In the present work, a facile and efficient route for the synthesis of a series of N-substituted imidazole derivatives is described. Docking studies have revealed that N-substituted imidazole derivatives based on (E)-urocanic acid may be potential an
Externí odkaz: https://doaj.org/article/c3f9c354ea824649b5becf16b8c22cf5
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4
Akademický článek
Multiple Sclerosis: Immunopathology and Treatment Update
Autor: Narges Dargahi, Maria Katsara, Theodore Tselios, Maria-Eleni Androutsou, Maximilian de Courten, John Matsoukas, Vasso Apostolopoulos
Publikováno v: Brain Sciences, Vol 7, Iss 7, p 78 (2017)
The treatment of multiple sclerosis (MS) has changed over the last 20 years. All immunotherapeutic drugs target relapsing remitting MS (RRMS) and it still remains a medical challenge in MS to develop a treatment for progressive forms. The most common
Externí odkaz: https://doaj.org/article/89095a8ebd5e4ab18be0903b78a8ce32
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6
Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions
Autor: Maria Evangelidou, Vivian Tseveleki, Ioannis Kanistras, Fotis Lampros, Hans Lassmann, Anastasia Dagkonaki, Maria-Eleni Androutsou, Irini Papazian, Theodore Tselios, Torben Ruhwedel, Lise T. Jensen, Maria Anagnostouli, Maria Avloniti, Lesley Probert, John Matsoukas, Wiebke Möbius
Publikováno v: Frontiers in Immunology
Dagkonaki, A, Avloniti, M, Evangelidou, M, Papazian, I, Kanistras, I, Tseveleki, V, Lampros, F, Tselios, T, Jensen, L T, Möbius, W, Ruhwedel, T, Androutsou, M E, Matsoukas, J, Anagnostouli, M, Lassmann, H & Probert, L 2020, ' Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions ', Frontiers in Immunology, vol. 11, 575451 . https://doi.org/10.3389/fimmu.2020.575451
Frontiers in Immunology, Vol 11 (2020)
CNS autoantigens conjugated to oxidized mannan (OM) induce antigen-specific T cell tolerance and protect mice against autoimmune encephalomyelitis (EAE). To investigate whether OM-peptides treat EAE initiated by human MHC class II molecules, we admin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aeb7385b0b831c52b951e62281ba380d
http://europepmc.org/articles/PMC7711156
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7
Characterization of Asparagine Deamidation in Immunodominant Myelin Oligodendrocyte Glycoprotein Peptide Potential Immunotherapy for the Treatment of Multiple Sclerosis
Autor: Maria-Eleni Androutsou, Theodore Tselios, Simona Golic Grdadolnik, Lesley Probert, Areti Gkika, Agathi Nteli, Anastasia Dagkonaki, Maria Avloniti
Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 7566, p 7566 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 20
Mannan (polysaccharide) conjugated with a myelin oligodendrocyte glycoprotein (MOG) peptide, namely (KG)5MOG35&ndash
55, represents a potent and promising new approach for the immunotherapy of Multiple Sclerosis (MS). The MOG35&ndash
55 epi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::489b243e2202de17b456403c458e80d7
https://www.mdpi.com/1422-0067/21/20/7566
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8
Cyclic citrullinated MBP87–99 peptide stimulates T cell responses: Implications in triggering disease
Autor: George Deraos, Vasso Apostolopoulos, Theodore Tselios, Stephanie Day, Lily Stojanovska, John Matsoukas, Minos-Timotheos Matsoukas, Maria-Eleni Androutsou
Publikováno v: Bioorganic & Medicinal Chemistry. 25:528-538
Amino acid mutations to agonist peptide epitopes of myelin proteins have been used to modulate immune responses and experimental autoimmune encephalomyelitis (EAE, animal model of multiple sclerosis). Such amino acid alteration are termed, altered pe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6086b561eeb2025d8349b32093c4f995
https://doi.org/10.1016/j.bmc.2016.11.029
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9
Gonadotropin-Releasing Hormone and GnRH Receptor: Structure, Function and Drug Development
Autor: Theodore Tselios, Maria-Eleni Androutsou, Agathi Nteli, Haralambos Tzoupis
Publikováno v: Current medicinal chemistry. 27(36)
Background: Gonadotropin-Releasing Hormone (GnRH) is a key element in sexual maturation and regulation of the reproductive cycle in the human organism. GnRH interacts with the pituitary cells through the activation of the Gonadotropin Releasing Hormo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee311876f8b7d990363081997828735
https://pubmed.ncbi.nlm.nih.gov/31309882
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