Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Maria-Cristina Keightley"'
Autor:
Hannah M Isles, Catherine A Loynes, Sultan Alasmari, Fu Chuen Kon, Katherine M Henry, Anastasia Kadochnikova, Jack Hales, Clare F Muir, Maria-Cristina Keightley, Visakan Kadirkamanathan, Noémie Hamilton, Graham J Lieschke, Stephen A Renshaw, Philip M Elks
Publikováno v:
eLife, Vol 10 (2021)
Neutrophils are rapidly recruited to inflammatory sites where their coordinated migration forms clusters, a process termed neutrophil swarming. The factors that modulate early stages of neutrophil swarming are not fully understood, requiring the deve
Externí odkaz:
https://doaj.org/article/d4579f2c9a1845eca0b84e65f16d27ae
Autor:
Ulf Schmitz, Natalia Pinello, Fangzhi Jia, Sultan Alasmari, William Ritchie, Maria-Cristina Keightley, Shaniko Shini, Graham J. Lieschke, Justin J-L Wong, John E. J. Rasko
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-15 (2017)
Abstract Background While intron retention (IR) is now widely accepted as an important mechanism of mammalian gene expression control, it remains the least studied form of alternative splicing. To delineate conserved features of IR, we performed an e
Externí odkaz:
https://doaj.org/article/9b968d71e3be43b4a85b98ccc47c942e
Autor:
Maria-Cristina Keightley, Duncan P. Carradice, Judith E. Layton, Luke Pase, Julien Y. Bertrand, Johannes G. Wittig, Aleksandar Dakic, Andrew P. Badrock, Nicholas J. Cole, David Traver, Stephen L. Nutt, Julia McCoey, Ashley M. Buckle, Joan K. Heath, Graham J. Lieschke
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Neutrophils are increased in response to injury and infection but how they form from a common granulocyte-macrophage progenitor is unclear. Here, the authors identify a role for the transcriptional repressor ZBTB11 in zebrafish, which is regulated by
Externí odkaz:
https://doaj.org/article/3c95ab3a3ca641e6961f1263d836b9c2
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23845 (2011)
Hematopoiesis requires the spatiotemporal organization of regulatory factors to successfully orchestrate diverse lineage specificity from stem and progenitor cells. Med12 is a regulatory component of the large Mediator complex that enables contact be
Externí odkaz:
https://doaj.org/article/e3049a45bf784fce84b80aff8f00f856
Autor:
Hannah M Isles, Catherine A Loynes, Sultan Alasmari, Fu Chuen Kon, Katherine M Henry, Anastasia Kadochnikova, Jack Hales, Clare F Muir, Maria-Cristina Keightley, Visakan Kadirkamanathan, Noémie Hamilton, Graham J Lieschke, Stephen A Renshaw, Philip M Elks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85572035fc572bbb86c4a2d49793c893
https://doi.org/10.7554/elife.68755.sa2
https://doi.org/10.7554/elife.68755.sa2
Autor:
Clare F. Muir, Catherine A. Loynes, Sultan Alasmari, Noémie Hamilton, Jack Hales, Fu Chuen Kon, Stephen A. Renshaw, Anastasia Kadochnikova, Katherine M. Henry, Visakan Kadirkamanathan, Maria-Cristina Keightley, Hannah M. Isles, Philip M. Elks, Graham J. Lieschke
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Neutrophils are rapidly recruited to inflammatory sites where their coordinated migration forms clusters, a process termed neutrophil swarming. The factors that modulate early stages of neutrophil swarming are not fully understood, requiring the deve
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Frontiers in Immunology
Frontiers in Immunology
Neutrophil nuclear morphology has historically been used in haematology for neutrophil identification and characterisation, but its exact role in neutrophil function has remained enigmatic. During maturation, segmentation of the neutrophil nucleus in
Publikováno v:
Seminars in celldevelopmental biology. 75
Splicing is a ubiquitous process in eukaryotic cells, long recognised as contributing to diversity of the transcriptome. More specifically, splicing fine-tunes the transcriptome output for highly individual outcomes at different stages of cell develo
Autor:
David Traver, Andrew P. Badrock, Aleksandar Dakic, Ashley M. Buckle, Maria-Cristina Keightley, Stephen L. Nutt, Judith E. Layton, Julia M. McCoey, Joan K. Heath, Graham J. Lieschke, Luke Pase, Johannes G. Wittig, Nicholas J. Cole, Julien Y. Bertrand, Duncan P. Carradice
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature communications, vol 8, iss 1
Nature Communications, Vol. 8 (2017) P. 14911
Keightley, M C, Carradice, D P, Layton, J E, Pase, L, Bertrand, J Y, Wittig, J G, Dakic, A, Badrock, A P, Cole, N J, Traver, D, Nutt, S L, McCoey, J, Buckle, A M, Heath, J K & Lieschke, G J 2017, ' The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger ', Nature Communications, vol. 8, 14911 . https://doi.org/10.1038/ncomms14911
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Nature communications, vol 8, iss 1
Nature Communications, Vol. 8 (2017) P. 14911
Keightley, M C, Carradice, D P, Layton, J E, Pase, L, Bertrand, J Y, Wittig, J G, Dakic, A, Badrock, A P, Cole, N J, Traver, D, Nutt, S L, McCoey, J, Buckle, A M, Heath, J K & Lieschke, G J 2017, ' The Pu.1 target gene Zbtb11 regulates neutrophil development through its integrase-like HHCC zinc finger ', Nature Communications, vol. 8, 14911 . https://doi.org/10.1038/ncomms14911
In response to infection and injury, the neutrophil population rapidly expands and then quickly re-establishes the basal state when inflammation resolves. The exact pathways governing neutrophil/macrophage lineage outputs from a common granulocyte-ma
All cells contain several multi-component molecular machines for executing steps in the fundamental cellular processes of transcription and translation. Paradoxically, despite their ubiquitous expression, individual components of these protein conglo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331a28570b9a15dfc788d09c97fb23f2
https://europepmc.org/articles/PMC5313294/
https://europepmc.org/articles/PMC5313294/