Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Maria-Christina Malinao"'
Autor:
Jennifer Louten,, Jeanine D. Mattson, Maria-Christina Malinao, Ying Li, Claire Emson, Felix Vega, Robert L. Wardle, Michael R. Van Scott, Robert B. Fick, Terrill K. McClanahan, Rene de Waal Malefyt, Maribel Beaumont
Publikováno v:
Biomarker Insights, Vol 2012, Iss 7, Pp 87-104 (2012)
Externí odkaz:
https://doaj.org/article/fd3fb9673f874c7d8dab8df2d3535926
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111714 (2014)
Ribonucleotide reductase (RNR) enzyme is composed of the homodimeric RRM1 and RRM2 subunits, which together form a heterotetramic active enzyme that catalyzes the de novo reduction of ribonucleotides to generate deoxyribonucleotides (dNTPs), which ar
Externí odkaz:
https://doaj.org/article/88e43e3666cf41e7b8d404431c0b901e
Autor:
Fernando Doñate, David R. Stover, Brian A. Mendelsohn, Michael Mattie, Zhilan Zeng, Melissa M. Williams, Mi Sook Chang, James Song, Sathish Kumar Ganesan, Maria Christina Malinao, Sara Gulesserian, Hui Zhao
Figure S1. Chemical structures of MMAF, MMAE and 13C5-MMAE. The asterisks indicate where Carbon-13 isotope has replaced Carbon-12; Figure S2. Expression of CD32 on mature neutrophils. Circulating neutrophils (AllCell) were incubated with anti-CD32 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660456dd4858e9bbebfdffd3e06f96c3
https://doi.org/10.1158/1535-7163.22508311
https://doi.org/10.1158/1535-7163.22508311
Autor:
Kei Yamada, James Song, Maria-Christina Malinao, Veronica Robles, Yutaka Matsuda, Brian A. Mendelsohn
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 1140
Antibody-drug conjugates (ADCs) have become major biopharmaceutical drugs in the field of oncology. Traditional ADCs possess a stochastic distribution of cytotoxic payloads linked to several different amino acid residues of the antibody. This heterog
Autor:
Mi Sook Chang, Fernando Donate, Michael D. Mattie, Sara Gulesserian, Melissa M. Williams, Sathish Kumar Ganesan, Zhilan Zeng, Hui Zhao, David R. Stover, Brian A. Mendelsohn, Maria-Christina Malinao, James Song
Publikováno v:
Molecular Cancer Therapeutics. 16:1866-1876
Neutropenia is a common adverse event in cancer patients treated with antibody–drug conjugates (ADC) and we aimed to elucidate the potential mechanism of this toxicity. To investigate whether ADCs affect neutrophil production from bone marrow, an i
Publikováno v:
Analytical chemistry. 91(20)
Antibody–drug conjugates (ADCs) have become a major class of oncology biopharmaceuticals. Traditional ADCs have a stochastic distribution of cytotoxic drugs attached at several different sites on the antibody. The heterogeneous nature of stochastic
Autor:
Akihiro Okada, Julien Dugal-Tessier, Maria-Christina Malinao, Brian A. Mendelsohn, John E Atkinson, Banmeet Anand, Josh Snyder
Publikováno v:
Molecular pharmaceutics. 15(6)
AGS62P1 is an antibody drug conjugate (ADC) composed of a human IgG1κ monoclonal antibody against FLT3 (FMS-like tyrosine kinase 3) with a p-acetyl phenylalanine (pAF) residue inserted at position 124 of each heavy chain linked to the proprietary mi
Autor:
Maribel Beaumont, Rene de Waal Malefyt, Jennifer Louten, Jeanine D. Mattson, Michael R. Van Scott, Robert L. Wardle, Terrill K. McClanahan, Claire Emson, Felix Vega, Robert B. Fick, Ying Li, Maria-Christina Malinao
Publikováno v:
Biomarker Insights
Biomarker Insights, Vol 7 (2012)
Biomarker Insights, Vol 2012, Iss 7, Pp 87-104 (2012)
Biomarker Insights, Vol 7 (2012)
Biomarker Insights, Vol 2012, Iss 7, Pp 87-104 (2012)
Background Biomarkers facilitate early detection of disease and measurement of therapeutic efficacy, both at clinical and experimental levels. Recent advances in analytics and disease models allow comprehensive screening for biomarkers in complex dis
Autor:
Maria-Christina Malinao, Manjari Nathan, Jeanine D. Mattson, Beth Basham, Maribel Beaumont, Harman S Paintal, Bela Desai, Ganesh Krishna, Rene de Waal Malefyt, Terrill K. McClanahan, James Canfield, Fran Shen, Robert B. Fick, Ying Li
Publikováno v:
Experimental lung research. 37(4)
Idiopathic interstitial pneumonias are a group of idiopathic interstitial lung diseases of which idiopathic pulmonary fibrosis (IPF) is the lesion of usual interstitial pneumonia. Although the pathogenic mechanisms remain incompletely understood, dis
Autor:
Robert B. Fick, Bela Desai, Ganesh Krishna, Maria-Christina Malinao, Harman S Paintal, Beth Basham, Maribel Beaumont, Ying Li, M Nathan, Jeanine D. Mattson, R. de Waal Malefyt, F Shen, Terri McClanahan, James Canfield
Publikováno v:
B60. PULMONARY FIBROSIS: THE FIBROBLAST.