Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Maria-Cecilia Lopez"'
Autor:
McKenzie K. Hollen, Julie A. Stortz, Dijoia Darden, Marvin L. Dirain, Dina C. Nacionales, Russell B. Hawkins, Michael C. Cox, Maria-Cecilia Lopez, Jaimar C. Rincon, Ricardo Ungaro, Zhongkai Wang, Quran Wu, Babette Brumback, Marie-Pierre L. Gauthier, Michael Kladde, Christiaan Leeuwenburgh, Mark Segal, Azra Bihorac, Scott Brakenridge, Frederick A. Moore, Henry V. Baker, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-16 (2019)
Abstract Background Sepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived
Externí odkaz:
https://doaj.org/article/6b9df6c997a446a79a45c0e33340dd88
Autor:
Dijoia B. Darden, Julie A. Stortz, McKenzie K. Hollen, Michael C. Cox, Camille G. Apple, Russell B. Hawkins, Jaimar C. Rincon, Maria-Cecilia Lopez, Zhongkai Wang, Eduardo Navarro, Jennifer E. Hagen, Hari K. Parvataneni, Maigan A. Brusko, Michael Kladde, Rhonda Bacher, Babette A. Brumback, Scott C. Brakenridge, Henry V. Baker, Christopher R. Cogle, Alicia M. Mohr, Philip A. Efron
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Older adults have significantly worse morbidity and mortality after severe trauma than younger cohorts. The competency of the innate immune response decreases with advancing age, especially after an inflammatory insult. Subsequent poor outcomes after
Externí odkaz:
https://doaj.org/article/0800739a2ae74d9f9aa89d5799441eb9
Autor:
Dijoia B. Darden, Gabriela L. Ghita, Zhongkai Wang, Julie A. Stortz, Maria-Cecilia Lopez, Michael C. Cox, Russell B. Hawkins, Jaimar C. Rincon, Lauren S. Kelly, Brittany P. Fenner, Tezcan Ozrazgat-Baslanti, Christiaan Leeuwenburgh, Azra Bihorac, Tyler J. Loftus, Frederick A. Moore, Scott C. Brakenridge, Henry V. Baker, Rhonda Bacher, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 15, p 3211 (2021)
Surgical sepsis has evolved into two major subpopulations: patients who rapidly recover, and those who develop chronic critical illness (CCI). Our primary aim was to determine whether CCI sepsis survivors manifest unique blood leukocyte transcriptome
Externí odkaz:
https://doaj.org/article/45388e6611df4968b051372eba23613d
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142931 (2015)
The African spiny mouse (Acomys spp.) can heal full thickness excisional skin wounds in a scar-free manner with regeneration of all dermal components including hair and associated structures. Comparing Acomys scar-free healing from Mus scarring ident
Externí odkaz:
https://doaj.org/article/75876e20d6504eb691d35f81aa2ca07b
Autor:
Sabyasachi, Bandyopadhyay, Tyler J, Loftus, Ying-Chih, Peng, Maria-Cecilia, Lopez, Henry V, Baker, Mark S, Segal, Kiley, Graim, Tezcan, Ozrazgat-Baslanti, Parisa, Rashidi, Azra, Bihorac
Publikováno v:
Shock. 58:20-27
Objective: The aim of this study was to characterize early urinary gene expression differences between patients with sepsis and patients with sterile inflammation and summarize in terms of a reproducible sepsis probability score. Design: This was a p
Autor:
Camille G. Apple, Elizabeth S. Miller, Hari K. Parvataneni, Alicia M. Mohr, Maria Cecilia Lopez, Tyler J. Loftus, Henry V. Baker, Jennifer E. Hagen, Philip A. Efron, Julie A. Stortz, Kolenkode B. Kannan, Matthew Patrick
Publikováno v:
Surgery
Background Previous data has shown that severe traumatic injury is associated with bone marrow dysfunction, which manifests as persistent injury-associated anemia. This study sought to identify whether the expression of erythropoiesis-related microRN
Autor:
Quran Wu, Henry V. Baker, Ricardo Ungaro, Maria-Cecilia Lopez, Azra Bihorac, Dina C. Nacionales, Lyle L. Moldawer, Alicia M. Mohr, Scott C. Brakenridge, Michael P. Kladde, Julie A. Stortz, Dijoia B Darden, Christiaan Leeuwenburgh, Marvin L. Dirain, Jaimar Rincon, Zhongkai Wang, Babette Brumback, Frederick A. Moore, Mark S. Segal, Marie-Pierre L. Gauthier, Philip A. Efron, McKenzie K. Hollen, Michael C. Cox, Russell B. Hawkins
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-16 (2019)
Critical Care
Critical Care
BackgroundSepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived suppressor
Autor:
Philip A. Efron, Henry V. Baker, Tezcan Ozrazgat-Baslanti, Lyle L. Moldawer, Maria-Cecilia Lopez, Rhonda Bacher, Tyler J. Loftus, Alicia M. Mohr, Michael C. Cox, Scott C. Brakenridge, Dijoia B Darden, Gabriela L. Ghita, Azra Bihorac, Christiaan Leeuwenburgh, Frederick A. Moore, Jaimar Rincon, Zhongkai Wang, Russell B. Hawkins, Lauren S Kelly, Brittany P Fenner, Julie A. Stortz
Publikováno v:
Journal of Clinical Medicine
Volume 10
Issue 15
Journal of Clinical Medicine, Vol 10, Iss 3211, p 3211 (2021)
Volume 10
Issue 15
Journal of Clinical Medicine, Vol 10, Iss 3211, p 3211 (2021)
Surgical sepsis has evolved into two major subpopulations: patients who rapidly recover, and those who develop chronic critical illness (CCI). Our primary aim was to determine whether CCI sepsis survivors manifest unique blood leukocyte transcriptome
Autor:
Maria-Cecilia Lopez, Scott C. Brakenridge, Lyle L. Moldawer, Ashrita Budharaju, Brittany P Fenner, Tyler J. Loftus, Philip A. Efron, Dijoia B Darden, Juan C. Mira, Julie A. Stortz, Dina C. Nacionales, Alicia M. Mohr, Frederick A. Moore, Henry V. Baker, Lauren S Kelly
Publikováno v:
J Trauma Acute Care Surg
BACKGROUND After severe trauma, the older host experiences more dysfunctional hematopoiesis of bone marrow (BM) hematopoietic stem and progenitor cells (HSPCs), and dysfunctional differentiation of circulating myeloid cells into effective innate immu
Autor:
Rajesh Mohandas, Azra Bihorac, Larysa Sautina, Mark S. Segal, Philip A. Efron, Lyle L. Moldawer, Ferdous Kadri, Frederick A. Moore, Henry V. Baker, Laura M Velez, Parisa Rashidi, Lasith Adhikari, Sabyasachi Bandyopadhyay, Ricardo Ungaro, Nicholas Lysak, Maria-Cecilia Lopez, Tezcan Ozrazgat-Baslanti, Scott C. Brakenridge, Ying-Chih Peng
Publikováno v:
Critical Care Explorations
Supplemental Digital Content is available in the text.
Objectives: Identify alterations in gene expression unique to systemic and kidney-specific pathophysiologic processes using whole-genome analyses of RNA isolated from the urinary cells of se
Objectives: Identify alterations in gene expression unique to systemic and kidney-specific pathophysiologic processes using whole-genome analyses of RNA isolated from the urinary cells of se