Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Maria-Antonietta Oliva"'
Autor:
Sara Ragucci, Veronica Russo, Angela Clemente, Maria Giuseppina Campanile, Maria Antonietta Oliva, Nicola Landi, Paolo Vincenzo Pedone, Antonietta Arcella, Antimo Di Maro
Publikováno v:
Toxins, Vol 16, Iss 3, p 135 (2024)
Ribosome inactivating proteins (RIPs) are specific N-β-glycosylases that are well-characterized in plants. Their enzymatic action is to damage ribosomes, thereby blocking protein translation. Recently, several research groups have been working on th
Externí odkaz:
https://doaj.org/article/e7a087fef7704ca198f92b27657697e8
Autor:
Sabrina Staffieri, Veronica Russo, Maria Antonietta Oliva, Marika Alborghetti, Miriam Russo, Antonietta Arcella
Publikováno v:
Molecules, Vol 28, Iss 16, p 6024 (2023)
Glioblastoma, the most dangerous and aggressive type of CNS tumor, appears resistant to many chemotherapy drugs. In the patient-derived glioma cell lines NULU and ZAR, which exhibit drug-resistant phenotypes, we investigated the effect of combined AE
Externí odkaz:
https://doaj.org/article/33152598c5374edaac2f427f0dad6d8f
Publikováno v:
Molecules, Vol 27, Iss 23, p 8335 (2022)
Isoginkgetin (Iso) is a natural bioflavonoid isolated from the leaves of Ginkgo biloba, this natural substance exhibits many healing properties, among which the antitumor effect stands out. Here we tested the effect of Iso on the growth of U87MG glio
Externí odkaz:
https://doaj.org/article/694a534f0af8401a820b2f72d8f4899e
Publikováno v:
Biomedicines, Vol 10, Iss 7, p 1583 (2022)
Cynaropicrin has shown a wide range of pharmacological properties, such as antitumor action. Here, we showed the inhibitory effect of Cyn on human glioblastoma cell U-87 MG growth. According to the IC50 values, Cyn 4, 8 and 10 µM displayed a signifi
Externí odkaz:
https://doaj.org/article/4611af544c094085a9f65e915c7135e2
Autor:
Rossella Rotondo, Sara Ragucci, Salvatore Castaldo, Nicola Landi, Maria Antonietta Oliva, Paolo V. Pedone, Antimo Di Maro, Antonietta Arcella
Publikováno v:
Molecules, Vol 27, Iss 8, p 2385 (2022)
Here, we propose Ageritin, the prototype of the ribotoxin-like protein family, as an adjuvant treatment to control the growth of NULU and ZAR, two primary human glioblastoma cell lines, which exhibit a pharmacoresistance phenotype. Ageritin is able t
Externí odkaz:
https://doaj.org/article/243dbeb3c4154dbcbcbaa98321cb5f53
Publikováno v:
Biology, Vol 10, Iss 9, p 870 (2021)
Glioblastoma is a brain tumour, characterised by recurrent or innate resistance to conventional chemoradiotherapy. Novel natural molecules and phyto-extracts have been proposed as adjuvants to sensitise the response to Temozolomide (TMZ). In this stu
Externí odkaz:
https://doaj.org/article/03c1d1f4e62449748e6b005e35fb6c98
Autor:
Rossella Rotondo, Sara Ragucci, Salvatore Castaldo, Maria Antonietta Oliva, Nicola Landi, Paolo V. Pedone, Antonietta Arcella, Antimo Di Maro
Publikováno v:
Toxins, Vol 13, Iss 10, p 684 (2021)
Ribosome-inactivating proteins (RIPs) are found in several edible plants and are well characterized. Many studies highlight their use in cancer therapy, alone or as immunoconjugates, linked to monoclonal antibodies directed against target cancer cell
Externí odkaz:
https://doaj.org/article/8d52fb8350494b4b8dd7339bfa4a3caf
Autor:
Rossella Rotondo, Maria Antonietta Oliva, Sabrina Staffieri, Salvatore Castaldo, Felice Giangaspero, Antonietta Arcella
Publikováno v:
Molecules, Vol 25, Iss 24, p 5843 (2020)
In this study, we propose lactucopicrin (LCTP), a natural sesquiterpene lactone from Lactucavirosa, as a molecule able to control the growth of glioblastoma continuous cell line U87Mg. The IC50 of U87Mg against LCTP revealed a strong cytotoxic effect
Externí odkaz:
https://doaj.org/article/23f0b43eedce4e2cab016dee8536b2f1
Autor:
Maria Antonietta Oliva, Rossella Rotondo, Sabrina Staffieri, Salvatore Castaldo, Massimo Sanchez, Antonietta Arcella
Publikováno v:
Journal of Chemotherapy. 34:173-183
p-Coumaric acid (pCA) is a hydroxycinnamic acid derivative commonly found in many natural products that has been extensively studied for its anticancer activity in multiple cell lines. In this repo...
Autor:
Maria Antonietta Oliva, Felice Giangaspero, Antonietta Arcella, Sabrina Staffieri, Salvatore Castaldo, Vincenzo Esposito
Publikováno v:
Journal of Neuro-Oncology. 151:123-133
Gliomas represent about 80% of primary brain tumours and about 30% of malignant ones, which today don’t have a resolution therapy because of their variability. A valid model for the study of new personalized therapies can be represented by primary