Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Maria-Andrea Mroginski"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract New variants of SARS-CoV-2 that can escape immune response continue to emerge. Consequently, there is an urgent demand to design small molecule therapeutics inhibiting viral entry to host cells to reduce infectivity rate. Despite numerous in
Externí odkaz:
https://doaj.org/article/c2a4df61709248e1a04f064d88bb48b4
Autor:
Huan Sun, Haiyang Jia, Olivia Kendall, Jovan Dragelj, Vladimir Kubyshkin, Tobias Baumann, Maria-Andrea Mroginski, Petra Schwille, Nediljko Budisa
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Sun et al. has studied the genetically encodable halotyrosines in proteins of the prokaryotic cell division machinery to elucidate the general role of halogenation in cellular lifespan and oxidative damage-induced diseases such as aging and cancer.
Externí odkaz:
https://doaj.org/article/16c257434def474fb0e926ce48e5732a
Autor:
Jovan Dragelj, Chara Karafoulidi-Retsou, Sagie Katz, Oliver Lenz, Ingo Zebger, Giorgio Caserta, Sophie Sacquin-Mora, Maria Andrea Mroginski
Publikováno v:
Frontiers in Microbiology, Vol 13 (2023)
Comprising at least a bipartite architecture, the large subunit of [NiFe]-hydrogenase harbors the catalytic nickel–iron site while the small subunit houses an array of electron-transferring Fe-S clusters. Recently, some [NiFe]-hydrogenase large sub
Externí odkaz:
https://doaj.org/article/02a657af90b84608b2fb67b319efd429
Autor:
Yuxuan Ji, Li Wei, Anqi Da, Holger Stark, Peter-Leon Hagedoorn, Simone Ciofi-Baffoni, Sally A. Cowley, Ricardo O. Louro, Smilja Todorovic, Maria Andrea Mroginski, Yvain Nicolet, Maxie M. Roessler, Nick E. Le Brun, Mario Piccioli, William S. James, Wilfred R. Hagen, Kourosh H. Ebrahimi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Externí odkaz:
https://doaj.org/article/14e01c9c674845c487345b274dc920b1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
The function of the recently isolated sulerythrin (SulE) has been investigated using a combination of structural and electronic analyses based on quantum mechanical calculations. In the SulE structure of Fushinobu et al. (2003), isolated from a stric
Externí odkaz:
https://doaj.org/article/c55b00588018492aab09a4ef5d92ffb3
Autor:
Yusaku Hontani, Mikhail Baloban, Francisco Velazquez Escobar, Swetta A. Jansen, Daria M. Shcherbakova, Jörn Weißenborn, Miroslav Kloz, Maria Andrea Mroginski, Vladislav V. Verkhusha, John T. M. Kennis
Publikováno v:
Communications Chemistry, Vol 4, Iss 1, Pp 1-11 (2021)
Near-infrared fluorescent proteins engineered from bacterial phytochromes are important for deep-tissue imaging in vivo, but the mechanism through which they bind to chromophores is not fully understood. Here the authors structurally analyze biliverd
Externí odkaz:
https://doaj.org/article/27b7026a2cc7487aa17fc5c6ab44f7c5
Autor:
Yang Yang, Till Stensitzki, Christina Lang, Jon Hughes, Maria Andrea Mroginski, Karsten Heyne
Publikováno v:
Photochemical & Photobiological Sciences. 22:919-930
Photoisomerization is a fundamental process in several classes of photoreceptors. Phytochromes sense red and far-red light in their Pr and Pfr states, respectively. Upon light absorption, these states react via individual photoreactions to the other
Autor:
Andrea Schmidt, Luisa Sauthof, Michal Szczepek, Maria Fernandez Lopez, Francisco Velazquez Escobar, Bilal M. Qureshi, Norbert Michael, David Buhrke, Tammo Stevens, Dennis Kwiatkowski, David von Stetten, Maria Andrea Mroginski, Norbert Krauß, Tilman Lamparter, Peter Hildebrandt, Patrick Scheerer
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Phytochromes are photoreceptors that are present in plants, bacteria and fungi. Here the authors present crystal structures of the phytochrome Agp2 from Agrobacterium fabrum in the parent Pfr state as well as a functional Meta-F intermediate and disc
Externí odkaz:
https://doaj.org/article/4a48f3e973d74e48ad18d6b2ef85136d
Publikováno v:
Applied Sciences, Vol 10, Iss 3, p 781 (2020)
The geometry and vibrational behavior of selenocysteine [NiFeSe] hydrogenase isolated from Desulfovibrio vulgaris Hildenborough have been investigated using a hybrid quantum mechanical (QM)/ molecular mechanical (MM) approach. Structural models have
Externí odkaz:
https://doaj.org/article/08bbeb0e42a943edbb091a1b4460277e
Autor:
Tillmann Utesch, Alejandra de Miguel Catalina, Caspar Schattenberg, Norman Paege, Peter Schmieder, Eberhard Krause, Yinglong Miao, J. Andrew McCammon, Vera Meyer, Sascha Jung, Maria Andrea Mroginski
Publikováno v:
mSphere, Vol 3, Iss 5 (2018)
ABSTRACT Fungal pathogens kill more people per year globally than malaria or tuberculosis and threaten international food security through crop destruction. New sophisticated strategies to inhibit fungal growth are thus urgently needed. Among the pot
Externí odkaz:
https://doaj.org/article/9c629bbaa8484a38b76934cafd8d7645