Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Maria do Carmo F. R. Pinto"'
Autor:
Maria do Carmo F. R. Pinto, Levy Tenorio Sousa Domingos, Leandro Figueira Reis de Sá, Rosangela Maria de Araújo Soares, Antonio Ferreira-Pereira, Daniel Clemente de Moraes
Publikováno v:
Revista Iberoamericana de Micología. 37:104-106
Background Mortality rate of invasive Candida infections is raising mainly amongst immunocompromised patients. These infections are hard-to-treat mainly due to the increasing incidence of resistance. The overexpression of ATP-binding cassette and maj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69d3882ae54aa02bab2d4be61d66a6cf
https://doi.org/10.1016/j.riam.2020.09.002
https://doi.org/10.1016/j.riam.2020.09.002
Autor:
Leida G. Abraçado, Priscilla Vanessa Finotelli, Maria C.S. Lourenço, Narjara Silveira, Raphael S. F. Silva, Suzana G. Leitão, Maria do Carmo F. R. Pinto, Pedro Eduardo Almeida da Silva, Mariana M. Longuinho
Publikováno v:
Materials Science and Engineering: C. 58:458-466
The aim of this work was to develop and characterize nanoparticles as carriers of lapazine, a phenazine derived from β-lapachone; its antimycobacterial activity is described for the first time as a potential treatment for tuberculosis. The lapazine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa0566db6509ea7e6da3057c2db9b4f5
https://doi.org/10.1016/j.msec.2015.08.062
https://doi.org/10.1016/j.msec.2015.08.062
Autor:
Tatiane S. C. Carvalho, Priscila Cristina Bartolomeu Halicki, Pedro Eduardo Almeida da Silva, Maria do Carmo F. R. Pinto, Laís A. Ferreira, Paula F. Carneiro, Kelly C. G. de Moura, Daniela Fernandes Ramos, Karina Pena Del Rio
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Frontiers in Microbiology
Frontiers in Microbiology
Despite being a curable disease, tuberculosis (TB) remains a public health problem worldwide mainly due to lengthy treatment, as well as its toxic effects, TB/HIV co-infection and the emergence of resistant Mycobacterium tuberculosis strains. These b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78139a6ad074ef18271ffb6e3152ffc
http://journal.frontiersin.org/article/10.3389/fmicb.2018.00673/full
http://journal.frontiersin.org/article/10.3389/fmicb.2018.00673/full
Anti-Mycobacterium tuberculosis activity of naphthoimidazoles combined with isoniazid and rifampicin
Autor:
Priscila Cristina Bartolomeu Halicki, Kelly C. G. de Moura, Karina Pena Del Rio, Lélia Pacheco Corrêa Barros, Maria do Carmo F. R. Pinto, Daniela Fernandes Ramos, Pedro Eduardo Almeida da Silva, Tatiane S. C. Carvalho
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 111
Tuberculosis (TB) is the cause of more than one million deaths worldwide, and despite being a curable disease, some factors can make therapy difficult, emphasizing the need for the development of new drugs that may potentiate the action of the classi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1863f312eea6bd3318e5e5b49fc82e9
https://pubmed.ncbi.nlm.nih.gov/30029908
https://pubmed.ncbi.nlm.nih.gov/30029908
Autor:
Ariadne Nunes Alonso, Anna Léa Silva Barreto, Kelly C. G. de Moura, José Alexandre Da Rocha Curvelo, Maristela Barbosa Portela, Maria do Carmo F. R. Pinto, Rosangela Maria de Araújo Soares, Rafaela S. Santana, Maria Teresa Vilela Romanos, Paula F. Carneiro, Camila A. dos Anjos
Publikováno v:
Medicinal Chemistry Research. 24:1155-1161
Candida species can cause infections that range from superficial to life-threatening events. Candida albicans is an opportunistic pathogen of human microbiota, and it is frequently described as a commensal organism, but in many cases, it can assume a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::736e97a9a2a9251c35875b70f20dc4b4
https://doi.org/10.1007/s00044-014-1202-y
https://doi.org/10.1007/s00044-014-1202-y
Autor:
Isadora M.M. de Melo, Vitor F. Ferreira, Tiago T. Guimarães, Juliane Sousa Lanza, Eufrânio N. da Silva Júnior, Maria do Carmo F. R. Pinto, Celso A. Camara, Rubens L. do Monte-Neto, Ronaldo N. de Oliveira, Frédéric Frézard, Wagner O. Valença, Maria Norma Melo, Emilay B. T. Diogo
Publikováno v:
European Journal of Medicinal Chemistry. 63:523-530
Continuing our screening program for novel anti-parasite compounds, we synthesized seven 1,4-naphthoquinones coupled to 1,2,3-triazoles, five nor-β-lapachone-based 1,2,3-triazoles and ten α-lapachone-based 1,2,3-triazoles. These and other naphthoqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52b19db07a7920fe06d22df45d18aab
https://doi.org/10.1016/j.ejmech.2013.02.038
https://doi.org/10.1016/j.ejmech.2013.02.038
Autor:
Paula F. Carneiro, Fernando de C. da Silva, Emerson Silva Lima, José Walkimar de M. Carneiro, Vitor F. Ferreira, Maria do Carmo F. R. Pinto, Maicon Delarmelina, Roberta K. F. Marra, Jackson A. L. C. Resende, Vinícius R. Campos
Publikováno v:
The Journal of organic chemistry. 81(13)
Starting from 2-hydroxy-1,4-naphthoquinone (lawsone), we synthesized eight new 6H-dibenzo[b,h]xanthene derivatives selectively under solvent-free conditions. Spectroscopic investigations confirmed that only the isomer 6H-dibenzo[b,h]xanthene was obta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9c54e8f7122cc8a9caed113b2597cb
https://pubmed.ncbi.nlm.nih.gov/27281677
https://pubmed.ncbi.nlm.nih.gov/27281677
Autor:
Kelly C. G. de Moura, Maria do Carmo F. R. Pinto, Pepita F. Polequevitch, Cleverson N. Pinto, Flavio da Silva Emery, Solange L. de Castro, A. V. Pinto, Andrea P. Dantas
Publikováno v:
Arzneimittelforschung. 50:1120-1128
The biological activities of the naphthoquinones lapachol and its cyclization product beta-lapachone, extracted from trees of the genus Tabebuia, have been intensively studied. Given continuity to the studies about heterocyclic derivatives obtained f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7abe57a46c6d3c54e861c4c507dee71
https://doi.org/10.1055/s-0031-1300337
https://doi.org/10.1055/s-0031-1300337
Autor:
Cláudia Pessoa, Carlos A. de Simone, Paula F. Carneiro, Kelly C. G. de Moura, Tatiane S. Coelho, Pedro Almeida da Silva, Antonio V. Pinto, Bruno C. Cavalcanti, Eufrânio N. da Silva Júnior, Nathália Martins de Oliveira, Renata G. Almeida, Maria do Carmo F. R. Pinto, Isabelle Karine da Costa Nunes
Publikováno v:
European Journal of Medicinal Chemistry. 46:4521-4529
Several quinonoid and phenazine compounds were synthesized in moderate to high yields and showed activity against H37Rv, rifampicin and isoniazid-resistance strains of Mycobacterium tuberculosis. The cytotoxity of the compounds were evaluated against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7054d6d17151dd4432a27946f75c20ff
https://doi.org/10.1016/j.ejmech.2011.07.026
https://doi.org/10.1016/j.ejmech.2011.07.026
Autor:
Janaína G. Soares, Carlos Eduardo M. Carvalho, José Dias de Souza Filho, William T. A. Harrison, Eufrânio N. da Silva Júnior, Maria do Carmo F. R. Pinto, Carlos A. de Simone, Antonio V. Pinto, José Rui M. Reys, Marília O. F. Goulart, Matuzalem J. da Silva
Publikováno v:
Tetrahedron Letters. 52(18):2415-2418
Bioactive naphthoquinone-derived heterocyclic compounds have been prepared. Herein, we describe the semisynthesis of a new phenazine, through modified Hooker’s reaction, using lapachol as a precursor. This compound was characterised by 2D NMR spect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bffa7a7a32c68e4496d164777b1c4f8b