Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Maria del Pilar Quintana"'
Autor:
Adebimpe Fasanya, Nurat Mohammed, Bandar Hasan Saleh, Muyideen Kolapo Tijani, Alexandra Teleka, Maria del Pilar Quintana, Lars Hviid, Kristina E. M. Persson
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Anemia is a common malaria-associated complication in pregnant women in endemic regions. Phosphatidylserine (PS) is exposed to the immune system during the massive destruction of red blood cells (RBCs) that accompany malaria, and antibodies against P
Externí odkaz:
https://doaj.org/article/2992ae90c642473f9b07ffeb6577ee1b
Autor:
Sai Sundar Rajan Raghavan, Robert Dagil, Mary Lopez-Perez, Julian Conrad, Maria Rosaria Bassi, Maria Del Pilar Quintana, Swati Choudhary, Tobias Gustavsson, Yong Wang, Pontus Gourdon, Michael Fokuo Ofori, Sebastian Boje Christensen, Daniel Thomas Remias Minja, Christentze Schmiegelow, Morten Agertoug Nielsen, Lea Barfod, Lars Hviid, Ali Salanti, Thomas Lavstsen, Kaituo Wang
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010924 (2022)
Malaria during pregnancy is a major global health problem caused by infection with Plasmodium falciparum parasites. Severe effects arise from the accumulation of infected erythrocytes in the placenta. Here, erythrocytes infected by late blood-stage p
Externí odkaz:
https://doaj.org/article/085ab7f662214893a8138336c02f4d83
Autor:
Henriette Hoffmann-Veltung, Nsoh Godwin Anabire, Michael Fokuo Ofori, Peter Janhmatz, Niklas Ahlborg, Lars Hviid, Maria del Pilar Quintana
Publikováno v:
eLife, Vol 11 (2022)
The issue of antibody cross-reactivity is of central importance in immunology, and not least in protective immunity to Plasmodium falciparum malaria, where key antigens show substantial allelic variation (polymorphism). However, serological analysis
Externí odkaz:
https://doaj.org/article/9e7e19c7292f4b0192ea86e0adeac26f
Autor:
Maria del Pilar Quintana
Publikováno v:
mSphere, Vol 6, Iss 3 (2021)
Maria del Pilar Quintana works on immunology and pathogenesis of severe malaria. In this mSphere of Influence article, she reflects on how the papers “Structural basis for placental malaria mediated by Plasmodium falciparum
Externí odkaz:
https://doaj.org/article/8e2a6dc0d2d34edbae6487a9f471742e
Autor:
Maria del Pilar Quintana, Jun-Hong Ch’ng, Kirsten Moll, Arash Zandian, Peter Nilsson, Zulkarnain Md Idris, Somporn Saiwaew, Ulrika Qundos, Mats Wahlgren
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-14 (2018)
Abstract Naturally acquired antibodies to proteins expressed on the Plasmodium falciparum parasitized red blood cell (pRBC) surface steer the course of a malaria infection by reducing sequestration and stimulating phagocytosis of pRBC. Here we have s
Externí odkaz:
https://doaj.org/article/9b4fd872e3274896a2e86a785a9a8e51
Autor:
Mads Delbo Larsen, Maria del Pilar Quintana, Sisse Bolm Ditlev, Rafael Bayarri-Olmos, Michael Fokuo Ofori, Lars Hviid, Peter Garred
Publikováno v:
Frontiers in Immunology, Vol 9 (2019)
Members of the PfEMP1 protein family are expressed on the surface of P. falciparum-infected erythrocytes (IEs), where they contribute to the pathogenesis of malaria and are important targets of acquired immunity. Although the PfEMP1-specific antibody
Externí odkaz:
https://doaj.org/article/be5f87e584cb4b97b27d003b646ae865
Publikováno v:
The Journal of Infectious Diseases.
Parasitemia among pregnant women with protective immunity to Plasmodium falciparum malaria is often dominated by VAR2CSA-positive infected erythrocytes (IEs). VAR2CSA mediates sequestration of IEs in the placenta. We hypothesized that the previously
Autor:
Maria Del Pilar Quintana, Jun-Hong Ch'ng, Arash Zandian, Maryam Imam, Kjell Hultenby, Michael Theisen, Peter Nilsson, Ulrika Qundos, Kirsten Moll, Sherwin Chan, Mats Wahlgren
Publikováno v:
PLoS ONE, Vol 13, Iss 8, p e0201669 (2018)
Plasmodium falciparum invasion into red blood cells (RBCs) is a complex process engaging proteins on the merozoite surface and those contained and sequentially released from the apical organelles (micronemes and rhoptries). Fundamental to invasion is
Externí odkaz:
https://doaj.org/article/f3c94bfdfbaf4c5f92fce8713b234861
Measuring Rosetting Inhibition in Plasmodium falciparum Parasites Using a Flow Cytometry-Based Assay
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2470
Rosetting is the ability of Plasmodium falciparum-infected erythrocytes (IEs) to bind to host receptors on the surface of uninfected erythrocytes (uE) leading to the formation of a cluster of cells with a central IE surrounded by uE. It is a hallmark
Autor:
Maria Del Pilar, Quintana
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2470
The genome of Plasmodium falciparum has an A/T content of around 81%. This, together with a high cysteine content and the high molecular weight of several proteins, make the expression of recombinant parasite proteins in heterologous systems challeng