Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Maria del Carmen Seleme"'
Autor:
Richard Cordaux, Maria del Carmen Seleme, Haig H. Kazazian, Laurel A Bastone, Melissa R. Vetter, Mark A. Batzer
Publikováno v:
Proceedings of the National Academy of Sciences. 103:6611-6616
Despite being scarce in the human genome, active L1 retrotransposons continue to play a significant role in its evolution. Because of their recent expansion, many L1s are not fixed in humans, and, when present, their mobilization potential can vary a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::163d60318185ca1ed671c7dd063e8d5e
https://doi.org/10.1073/pnas.0601324103
https://doi.org/10.1073/pnas.0601324103
Autor:
Maria del Carmen Seleme, Stéphanie Robin, Danielle Teninges, Olivier Disson, Alain Bucheton, Christine Brun
Publikováno v:
Nucleic Acids Research
According to the current model of non-LTR retrotransposon (NLR) mobilization, co-expression of the RNA transposition intermediate, and the proteins it encodes (ORF1p and ORF2p), is a requisite for the formation of cytoplasmic ribonucleoprotein comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a24202ab011bffa69e587b2f903520d4
http://europepmc.org/articles/PMC548363
http://europepmc.org/articles/PMC548363
Autor:
D.V Babusho, Maria del Carmen Seleme, Haig H. Kazazian, P.K. Mandal, Melissa R. Vetter, D.M. Ostertag
Publikováno v:
Retrotransposition, Diversity and the Brain ISBN: 9783540749653
The L1 retrotransposon is amajor component ofmammalian genomes and hasmolded them throughout evolution in many ways, thereby expanding the possibilities for human diversity. In this paper,we discuss one further mechanism bywhich L1 can alter the geno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::791d0b7f68254026f626398c54ca01f2
https://doi.org/10.1007/978-3-540-74966-0_5
https://doi.org/10.1007/978-3-540-74966-0_5
Autor:
Paulus T. V. M. de Jong, Iwan C. Meij, Erik A. Sistermans, Frans P.M. Cremers, Haig H. Kazazian, Astrid S. Plomp, Ilse J. de Wijs, Lies H. Hoefsloot, Konstantinos Nikopoulos, Maria del Carmen Seleme, Arijit Mukhopadhyay, José A. J. M. van den Hurk, Hiroki Kano
Publikováno v:
Human molecular genetics, 16(13), 1587-1592. Oxford University Press
Human Molecular Genetics, 16(13), 1587-1592. Oxford University Press
Human Molecular Genetics, 16, 1587-92
van den Hurk, J A J M, Meij, I C, del Carmen Seleme, M, Kano, H, Nikopoulos, K, Hoefsloot, L H, Sistermans, E A, de Wijs, I J, Mukhopadhyay, A, Plomp, A S, de Jong, P T V M, Kazazian, H H & Cremers, F P M 2007, ' L1 retrotransposition can occur early in human embryonic development ', Human Molecular Genetics, vol. 16, no. 13, pp. 1587-1592 . https://doi.org/10.1093/hmg/ddm108
Human Molecular Genetics, 16, 13, pp. 1587-92
Human Molecular Genetics, 16(13), 1587-1592. Oxford University Press
Human Molecular Genetics, 16, 1587-92
van den Hurk, J A J M, Meij, I C, del Carmen Seleme, M, Kano, H, Nikopoulos, K, Hoefsloot, L H, Sistermans, E A, de Wijs, I J, Mukhopadhyay, A, Plomp, A S, de Jong, P T V M, Kazazian, H H & Cremers, F P M 2007, ' L1 retrotransposition can occur early in human embryonic development ', Human Molecular Genetics, vol. 16, no. 13, pp. 1587-1592 . https://doi.org/10.1093/hmg/ddm108
Human Molecular Genetics, 16, 13, pp. 1587-92
Contains fulltext : 52357.pdf (Publisher’s version ) (Closed access) L1 elements are autonomous retrotransposons that can cause hereditary diseases. We have previously identified a full-length L1 insertion in the CHM (choroideremia) gene of a patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8423a095d4e97af4c19391564d4480
https://pure.amc.nl/en/publications/l1-retrotransposition-can-occur-early-in-human-embryonic-development(7f9d39c1-91fe-422b-9d80-acf194105a3f).html
https://pure.amc.nl/en/publications/l1-retrotransposition-can-occur-early-in-human-embryonic-development(7f9d39c1-91fe-422b-9d80-acf194105a3f).html
Autor:
Maria del Carmen Seleme, Noriyuki Kasahara, Shuji Kubo, José Luis Garcia Perez, Haig H. Kazazian, Harris S. Soifer, John V. Moran
Whether long interspersed element-1 (L1 or LINE-1) retrotransposition can occur in quiescent, nondividing, and/or terminally differentiated somatic cells has remained an unanswered fundamental question in human genetics. Here, we used a ubiquitously
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c14b964fb4712805a20e6554efb06fd
https://europepmc.org/articles/PMC1472425/
https://europepmc.org/articles/PMC1472425/
Autor:
Eric M. Ostertag, Haig H. Kazazian, Maria del Carmen Seleme, Kurt A. Engleka, John L. Goodier
Publikováno v:
Human molecular genetics. 13(10)
Determining the subcellular localization of the L1 ORF2 protein (ORF2p) has been impossible to date because of technical limitations in detecting either endogenous or overexpressed forms of the protein. Here we report visualization of the full-length
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0811bd50a68ba37761eaf558c91af039
https://pubmed.ncbi.nlm.nih.gov/15028673
https://pubmed.ncbi.nlm.nih.gov/15028673
Autor:
Isabelle Busseau, Sophie Malinsky, Alain Bucheton, Maria-del-Carmen Seleme, Danielle Teninges
Publikováno v:
Genetics. 151(2)
To study the expression of the I factor, a non-long-terminal-repeat retrotransposon responsible for I-R hybrid dysgenesis in Drosophila melanogaster, we have tagged the ORF1 protein (ORF1p) by inserting the HA epitope in its N-terminal region. In tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e6c30dbf7a845a6086b86d08395d769
https://pubmed.ncbi.nlm.nih.gov/9927467
https://pubmed.ncbi.nlm.nih.gov/9927467
Autor:
Maria del Carmen Seleme, Eric M. Ostertag, Hiroki Kano, Christine Courtney, Daria V. Babushok, Nuo Yang, Haig H. Kazazian
Publikováno v:
Retrovirology
LINE-1 or L1 retrotransposons have accounted for 1/3 of the genomes of humans and other mammals through direct insertion and mobilization of other DNAs, such as Alus and processed pseudogenes. In this talk, I discuss two recent "surprises" in our stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53c3d2009058da2e38d1668a7e83249
http://europepmc.org/articles/PMC1716967
http://europepmc.org/articles/PMC1716967