Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Maria del Carmen Domínguez-Horta"'
Autor:
Maria del Carmen Domínguez-Horta, Anabel Serrano-Díaz, Mabel Hernández-Cedeño, Gillian Martínez-Donato, Gerardo Guillén-Nieto
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Cytokines are secretion proteins that mediate and regulate immunity and inflammation. They are crucial in the progress of acute inflammatory diseases and autoimmunity. In fact, the inhibition of proinflammatory cytokines has been widely tested in the
Externí odkaz:
https://doaj.org/article/074243b55e61448c81c8bd1958e8e95e
Autor:
Rita Cimino, Marco Savioli, Noemi Ferrante Carrante, Ernesto Placidi, Hilda Garay-Perez, Matilde López-Abad, Alexis Musacchio Lasa, Maria Del Carmen Domínguez-Horta, Emanuela Gatto, Francesca Cavalieri, Gianfranco Bocchinfuso, Mariano Venanzi
Publikováno v:
ChemPhysMater, Vol 1, Iss 1, Pp 62-70 (2022)
The biological properties of therapeutic peptides, such as their pharmacokinetics and pharmacodynamics, are correlated with their structure and aggregation properties. Herein, we studied the aggregation properties of a therapeutic peptide (CIGB-814),
Externí odkaz:
https://doaj.org/article/5f3a208a86444090981c342f0f4f41ef
The biological properties of therapeutic peptides, such as their pharmacokinetics and pharmacodynamics, are correlated with their structure and aggregation properties. Herein, we studied the aggregation properties of a therapeutic peptide (CIGB-814),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______2659::62b6323939b97f1247c0ff08c044a788
https://zenodo.org/record/7804117
https://zenodo.org/record/7804117
Autor:
Hilda Garay-Perez, Alexis Musacchio Lasa, Emanuela Gatto, Gianfranco Bocchinfuso, Francesca Cavalieri, Mariano Venanzi, Maria Del Carmen Domínguez-Horta, Ernesto Placidi, Marco Savioli, Rita Cimino, Matilde López-Abad, Noemi Ferrante Carrante
The biological properties of therapeutic peptides, such as their pharmacokinetics and pharmacodynamics, are correlated with their structure and aggregation properties. Herein, we studied the aggregation properties of a therapeutic peptide (CIGB-814),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39774739d5f3a35e0b4481f93fc1a290
http://hdl.handle.net/2108/284477
http://hdl.handle.net/2108/284477
Autor:
Rafael Venegas-Rodríguez, Anabel Serrano-Díaz, Ruben Peña-Ruiz, Raul Santana-Sánchez, Mabel Hernández-Cedeño, Aliusha Rittoles Navarro, Inti Grecesqui-Cruz, Liam Pérez-Aguilera, Anadys Segura-Fernández, Leticia Rosario-Cruz, Gilliam Martínez-Donato, Gerardo Guillén-Nieto, Maria del Carmen Domínguez- Horta
Publikováno v:
PLOS ONE. 18:e0281111
This paper presents the results of an observational and retrospective study on the therapeutic effects of Jusvinza, an immunomodulatory peptide with anti-inflammatory properties for critically ill COVID-19 patients. This peptide induces regulatory me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f8c506891f0d509266f0250f59db238
https://doi.org/10.1371/journal.pone.0281111
https://doi.org/10.1371/journal.pone.0281111
Autor:
Ana Marta López, Luis Javier González, Laura Hernández, Jorge A. Gómez, Maria del Carmen Domínguez Horta, Yusimy Reyes, Dinorah Prada, Oreste Corrales
Publikováno v:
Clinical Rheumatology. 38:955-960
Rheumatoid arthritis (RA) is a chronic T cell-mediated autoimmune disease. Serum autoantibodies against cyclic citrullinated peptides (anti-CCP) are significant markers for diagnosis and prognosis of this disease. Induction of immune tolerance as the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::237e00bb3397500539f684f707844b26
https://doi.org/10.1007/s10067-018-4360-3
https://doi.org/10.1007/s10067-018-4360-3
Autor:
Kyung-Hyun Cho, Yunki Lee, Sang Hyuk Lee, Ji-Eun Kim, Ashutosh Bahuguna, Maria del Carmen Dominguez-Horta, Gillian Martinez-Donato
Publikováno v:
Antioxidants, Vol 13, Iss 9, p 1049 (2024)
CIGB-258 is known to exert anti-inflammatory activity via structural stabilization of apolipoprotein A-I (apoA-I) and functional enhancement of high-density lipoproteins (HDL) against acute toxicity of carboxymethyllysine (CML). The co-presence of CI
Externí odkaz:
https://doaj.org/article/f39c32420b1243ae9daeaf842b2f287c
Autor:
Alfredo Hernández, Yolanda Cruz, Yusimy Reyes, Ania Cabrales, Norailys Lorenzo, Claudio Molinero, Jorge A. Gómez, Osmel Martinez, Gabriel Padrón, Hilda Garay, Luis Javier González, Vladimir Besada, Leonardo Oramas, Oreste Corrales, Yisel Avila, E. Pérez, Lina Pérez, Maria del Carmen Domínguez Horta, Cabal Carlos, Osvaldo Reyes, Dinorah Prada, Yassel Ramos, Ana Marta López, E González, Yaysel Miñoso, M. López, Yuliet Bermudez
Publikováno v:
Journal of Clinical Trials.
Background: CIGB 814 is an Altered Peptide Ligand (APL) from a CD4+ T-cell epitope of human heat shock protein 60 (HSP60), an auto-antigen involved in the pathogenesis of rheumatoid arthritis (RA). It induced mechanisms associated with restoration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5736d273a88b77d77c56b0b9a0ec296d
https://doi.org/10.4172/2167-0870.1000339
https://doi.org/10.4172/2167-0870.1000339
Autor:
Kyung-Hyun Cho, Ji-Eun Kim, Dae-Jin Kang, Maria del Carmen Dominguez-Horta, Gillian Martinez-Donato
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 165 (2024)
CIGB-258 is a 3 kDa altered peptide ligand from heat shock protein (HSP) 60 that exhibits anti-inflammatory activity against the acute toxicity of carboxymethyllysine (CML) with antioxidant and anti-glycation activities via protection of high-density
Externí odkaz:
https://doaj.org/article/bd9d44cec1a948829c66938dca84e8e7